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다양한 헤마토크릿(Hematocrit)치에 대한 혈액 모사 용액 개발
송상민(Sangmin Song),고승빈(Seungbin Ko),송시몬(Simon Song) 대한기계학회 2018 대한기계학회 춘추학술대회 Vol.2018 No.12
As the incidence of vascular disease increases, the need for blood analog fluids for hemodynamic analysis is increasing. Most previous studies have focused on the blood analog fluid for normal hematocrit which is approximately 40%. This study presents an explicit approach to the development of blood analog fluid with various hematocrit values. We use a mixture of xanthan gum, glycerin and deionized water as the blood analog fluid and investigate the effect of mass fraction of each component on the viscosity behavior. As a result, the xanthan gum was found to have an effect on increasing slope of graph by increasing viscosity at low shear rate, and the glycerin was found to have an influence on increasing overall viscosity values. We expect that the results of this study would contribute to wide range of studies that require blood analog fluids.
자기공명유속계를 이용하여 예측한 벽면전단응력의 정확도 평가 기준 개발
이지수(Jeesoo Lee),고승빈(Seungbin Ko),양병권(Byungkuen Yang),조지현(Jee-Hyun Cho),송시몬(Simon Song) 대한기계학회 2018 대한기계학회 춘추학술대회 Vol.2018 No.12
Wall shear stress (WSS) exerted on a blood is one of the key factors associated with cardiovascular diseases. It has been found that magnitude and temporal oscillation of WSS can be correlated with atherosclerosis, aortic dilatation and vascular remodeling. Magnetic resonance velocimetry (MRV) is currently the most advanced technique that can noninvasively estimate temporal and volumetric distribution WSS in vivo. Numerous clinical studies have been reported which determined WSS in various vascular region based on MRV measurements. However, it is difficult to discover the descriptions about the absolute accuracy of WSS in literatures, especially in clinical studies because the true value of WSS is unknown. Therefore, a facile criterion for assessing the accuracy of estimated WSS for MRV measurements with unknown WSS would be valuable. In this research, we propose a novel criterion called Reynolds resolution to assess the absolute accuracy of WSS estimated from MRV data. It is described with measurement parameters and thus, can readily be calculated. We investigated the relation between the Reynolds resolution and WSS accuracy by measuring pressuredriven laminar circular tubing flows and a proportional relation was found indicating that the Reynolds resolution could have its potential to be used for predicting the absolute errors of MRV-estimated WSS.