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Cyclosporin A로 관해를 유도한 Steroid 저항성 미세변화형 신증후군이 병발된 IgA 신병증 1예
김병길,정현주,최인준,이종균,배기수,고세중 대한신장학회 1988 Kidney Research and Clinical Practice Vol.7 No.1
We report a case of an 8 year-old-girl with steroid resistant nephrotic syndrome with pathologic features of minimal change disease and deposition of IgA in the mesangial regions. She was treated with corticosteroid for 4 weeks without an initial response, and then pulse therapy was tried without effect. Cyclosporin A was then administered with corticosteroid for 6 months and remission was successfully induced. We discussed the concomittent presence of both minimal lesion nephrotic syndorme and IgA nephropathy, and their possible pathogenesis including T-cell abnormalities are reviewed.