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내분비장애물질에 노출된 넙치의 호흡대사와 혈액화학적 변화
김홍윤(H.Y. Kim),조현서(H.S. Cho),강현배(H.B. Kang) 한국해양환경·에너지학회 2004 한국해양환경공학회 학술대회논문집 Vol.2004 No.-
cute and chronic toxicity studies, using four compounds tributyltin (TBT), benzo(a)pyrene aP), nonylphenol (NP) and bisphenol A (BPA), were performed on olive flounder, Paralichthys vaceus. The 96 hr-LC50 for TBT, BaP, NP and BPA at 21.1±0.3℃ were 16, 25, 140 and 1100ppb, respectively. The chronic tests were flow-through method in the concentration of 5% (low conc.) and 10% (high conc.) to 96 hr-LC50, and run for 62 days. In the case of the flounder which exposed to each compound, growth rates of body weight were significantly decreased and serum glucose levels were elevated as compared to control value. Oxygen consumption rate was remarkably increased by exposing fish to sub-lethal concentration of each compound.