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      • 한국 섬집단에 있어서 D.melanogaster의 효소좌위와 염색체간의 연관관계

        강영순,김욱,Kang, Young-Soon,Kim, Wook 한국통합생물학회 1992 동물학회지 Vol.35 No.1

        한국의 세 섬집단으로부터 채집한 Drosophila melanogaster를 대상으로 465개의 haploid genome을 추출한 후, 제 2염색체 상에 위치한 Gpdh와 각서 유전자 및 In(2I)t의 빈도를 조사하여 이들간의 연관관계를 분석한 결과 Gpdh와 Adh 효소 좌위 사이 에 유의 한 연관 불평형 이 제주도와 울릉도집 단에서 관찰되었으며 , Gpdh와 In(2I)t, Adh와 In(21)t 사이에 모두 유의한 연관 불평형이 제주도, 영종도 그리고 울릉도집단에서 관찰되었다. 조사된 전체 genome들 중에서 In(21)t 를 가지고 있는 염색체의 98%(48/49)가 Gpdhf와 Adhs형으로 연관된 결과를 보였다. 이러한 결과들로 볼 때 이들 효소 좌위 사이에 나타난 연관 불평형은 In(21)t와의 hitchhiking현상에 의해 나타난 결과로 해석되며 본 섬집단에서 그 정도가 더 심한 것으로 확인되었다.

      • KCI등재

        인도네시아 파푸아 천연자원 개발의 주체인 다국적기업의 사례: 프리포트 인도네시아를 중심으로

        강영순 ( Kang Young Soon ) 한국외국어대학교 동남아연구소 2018 東南亞硏究 Vol.28 No.2

        It has been a fact that the Freeport Indonesia Company has been playing a positive role in the industry through its involvement in the gold and copper mine sector. However, the actions also result in serious environmental destructions and pollution to the local society. Besides focusing on the environmental problems, human rights, and the conflicts arise among the local community, this thesis also analyses the important factors that contribute to the positive development of Papua. Through the export of mineral resources, royalty and tax, Freeport contributes plenty in the economy of the country and the province. Freeport improves the adverse effects, focusing on the development and the welfare of the local community, Environmental friendly management, understanding of the local traditional practices by the local community. Through these, Freeport continues to develop and practice a diverse ways of policies for the people living within the mining area and its society. On the other hand Freeport is running the Controlled Riverine Tailings Management program (or SIRSAT), reclamation and re-vegetation program, environmental management program, waste and energy management program, biodiversity conservation program, local people employment, local education support program, hospital construction and medical support, health and safety program, human rights education, programs for local economic independence etc. It shows that Freeport is concentrating on the living of the local society through its way of management. However, there are still problems to be solved. The mining area has been decreased according to the contract and the loyalty has been increased. The current president Joko Widodo is addressing this issue with the raise of the percentage of shareholding and the extend of the contract on the smelting factory. As such, not only the issue of shareholding and the smelting factory is addressed, however, the extention of the contract, local environment problem and land compensation are involved as well with the land compensation issue being the most sensitive matter. It is anticipated that if the problem of land compensation and the extention of contract are solved prior to any other issue and obtain the cooperation from the local community, Freeport can be a valuable contributor to the development of Papua.

      • KCI등재후보

        리더십 유형, 정서적 반응, 혁신행동간의 구조적 관계

        강영순(Young Soon Kang),양덕순(Duk Soon Yang) 한국경영사학회 2007 經營史學 Vol.45 No.-

        This study endeavors to find out the best model in the constructional relationship between several factors. The constructional relationship composed of the three types of leadership pattern (i.e., change-oriented leadership, relations-oriented leadership and sacrificial leadership) and the self-efficacy, job motivation, innovational behavior as the emotional responses of subordinate. Based on the four competitive models, several Chi-square difference tests on each model are implemented. As a result, this study shows the following optimal model; two types of leadership(change-oriented leadership, sacrificial leadership) affect positively the self-efficacy of subordinates. The sacrificial leadership gives the indirect impact on the Innovational Behavior through the self-identification and job-motivation. The fitness of the model is found to be χ2=609.915, df=338, p<.001, GFI=0.870, NFI=.897, CFI=0.951, RMR=0.039. The main points of this study are; first, the two factors which the new leadership paradigm requires are selected for the study. Of the two factors, the former is the innovational behavior through which the important flexibility in the leadership measurement is measured. The latter is the self-efficacy and the job motivation which are the emotional responses of subordinates. Finally, this paper provides the useful information for the application toward the real world by categorizing the leader behaviors as the three types through the previous literature survey.

      • KCI등재

        인도네시아 파푸아의 산림자원과 미래: 환경자원의 개발과 딜레마

        강영순 ( Young Soon Kang ) 한국외국어대학교 동남아연구소 2016 東南亞硏究 Vol.25 No.3

        This research focuses on Papua Indonesia, a region where natural resources are abundant. However, poor local development and the lack of effective planning and execution have prevented the rich resources from being fully utilized. The development in Papua Indonesia needs proper construction of infra facilities which based on the environment and social factors. Large capital and advance technology is a must in the process but problems have been surfacing throughout the whole process. Despite the various difficulties, Indonesia state government is still making effort trying to develop the region and thus this has instead turned into a dilemma to the local government. This research focuses on the dilemmas and the future of Papua`s future development. The future of Papua depends largely on its natural resources. This research is divided into a few categories: the necessity and the factors of proper development, present situation of Papua forest resources, the policies made by the central government and the state government, the development of the resources and its dilemmas, and the future of Papua. Despite the rich natural resources that Papua holds, the management of human resource development regarding the local people has never been carried out effectively. As a result, not only that the local people and the government could not receive any kinds of benefits from the resources, but they also suffers from the feeling of loss economically. Hence, there is a need to develop the resources for the benefits of the local people. Efforts have been carrying out from time to time but the dilemmas resulted from the development has always been a problem. Besides, those dilemmas also affect activities like logging, mining of minerals, and the construction of infrastructures. National interest versus forest development, regional development project and the increase of local population, development versus the destruction of nature environment are just a few examples of the dilemmas to be considered. The future of Papua is directly connected to its natural resources. The central government and the state government should put serious consideration on range and the period of the development. Also, the local people should be educated and be informed about the development of the region. On the other hand, developers who are involved in the project shall come out with a plan to minimize the damage to the environment and increase the infrastructures around the area to improve the living of the local people. By doing this, not only the dilemmas could be overcome, but a better future for both Papua and future generation can be ensured.

      • KCI등재

        마우스 C2C12 근관세포에서 AICAR로 유도된 근위축에 미치는 오미자 추출물의 영향

        강영순(Young-Soon Kang),박철(Cheol Park),한민호(Min-Ho Han),홍수현(Su-Hyun Hong),황혜진(Hye-Jin Hwang),김병우(Byung Woo Kim),김철민(Cheol Min Kim),최영현(Yung Hyun Choi) 한국생명과학회 2015 생명과학회지 Vol.25 No.3

        근위축은 근육 단백질 합성의 저하와 근육 단백질의 분해 증가에 따른 근섬유의 감소에 의한 근육량이 감소되는 현상이다. 오미자(Schisandrae Fructus, fruits of Schisandra chinensis (Turcz.) Baillon)는 오랫동안 전통의학에서 강장제로서 널리 사용되어 왔다. 비록 다양한 질병 연관 오미자의 생리활성 효능이 폭넓게 연구되어져 왔으나 근육 질환 관련 연구는 매우 제한적으로 이루어져 왔다. 본 연구에서는 오미자 에탄올 추출물(SF)이 AMPK 활성인자 AICAR 처리에 의한 C2C12 근관세포의 근위축 모델계를 이용하여 근위축 억제 효능을 가지는지의 여부와 관련 기전의 해석을 시도하였다. AICAR 처리는 근단백질 분해 연관 ubiquitin ligase muscle RING finger-1 (MuRF-1)의 발현을 전사 수준에서 증가시켰고, MuRF-1 조절 전사인자의 하나인 forkhead box O3a (FoxO3a) 단백질의 인산화를 증가시켰으며, 이러한 변화는 근위축과 연관된 C2C12 근관세포의 형태적 변형과 동반된 현상이었다. 그러나 SF의 전처리에 의하여, AICAR에 의하여 유도된 근위축성 형태변화를 억제하였으며, MuRF-1의 발현과 FoxO3a의 활성화를 억제시켰다. 본 연구의 결과는 SF가 AICAR 처리에 의한 C2C12 근관세포의 근위축을 AMPK 및 FoxO3a 신호전달계 조절을 통하여 억제하였음을 보여주는 것으로 오미자는 근기능 향상을 위한 식의 약 소재로서의 개발 가능성이 매우 높음을 시사하여 준다. Muscle atrophy, known as a sarcopenia, is defined as a loss of muscle mass resulting from a reduction in the muscle fiber area or density due to a decrease in muscle protein synthesis and an increase in protein breakdown. Schisandrae fructus (SF) extract of the fruits of Schisandra chinensis (Turcz) Baillon has been used as a tonic in traditional medicine for thousands of years. Although a great deal of work has been carried out on the therapeutic potential of SF, its pharmacological mechanisms of action in muscle diseases actions remain unclear. In the present study, we investigated the inhibitory effects of SF ethanol extracts on the production of muscle atrophy factors in C2C12 myotubes stimulated with 5-aminoimidazole-4-carboxamide-ribonucleotide (AICAR), an AMP-activated kinase (AMPK) activator, and sought to determine the underlying mechanisms of action. AICAR upregulated atrophy-related ubiquitin ligase muscle RING finger-1 (MuRF-1) and stimulated the levels of the forkhead box O3a (FoxO3a) transcription factor in the C2C12 myotubes. SF supplementation effectively and concentration-dependently counteracted AICAR-induced muscle cell atrophy and reversed the increased expression of MuRF-1 and FoxO3a. Our study demonstrates that SF can reverse the muscle cell atrophy caused by AICAR through regulation of the AMPK and FoxO3a signaling pathways, followed by inhibition of MuRF-1.

      • KCI등재
      • KCI등재

        동아시아 순환오류형 형식담의 우언적 소통 비교연구 -〈야서혼〉 유형을 중심으로-

        강영순 ( Young Soon Kang ) 한민족어문학회 2004 韓民族語文學 Vol.45 No.-

        Mole or Mouse`s Marriage, a folktale known as Stronger and Strongest in Europe, is highly Idiosyncratic not on account of the story of looking for son-in-law, but on accont of the exact form in which the story is narrated. It is a formula tale that tell a problem of circular argument, i e circular fallacy in point of which the final circulation is on the former place. In such tale, only if maintaining the form of narrative, the story is differntly modified as much as It can Therefore the folktale type has deeply relation with the other formula tales of cicular fallacy Speaking by the concept borrowed from Yogacara-Buddhism, the allegorical meaning of cicular-fallecy`s formula tale is devided broadly into two categories, perceiving one and wandering one The former is brought forth a awakening spiritual enlightenment, the latter is only repeated by the circulation of mistake It is about Mole`s Marrage, Naming A Pet Cat, A Mason, and Who is Stronger etc that we can comprehend each allegorical meaning in view of such circular argument of Yogacara-Buddhism. Also there is a tale type that has the two-fold meaning at the same time. In Korea, Mole`s Marrage was main type among the formula tale of circular fallacy It`s allegorical meaning was diversified between perceiving and wandering categories But also it`s meaning was varied by literary-bureaucrats in the latter Choson-dynasty. In China, the class of intelligentsia concentrated upon severe satire and reflection as allegorical meaning of it, on the other hand it`s relational realm was Widened into the play, annual painting, and New Year`s ritual ceremony. And in Japan, the folktale was made useful of governing ideology through the allegorical meaning. The work, as moral text, persuaded hearers or readers to keep one`s status, and prevent them not to pursue their desire of social ascent to upper class

      • 지방정부간 협력 거버넌스의 영향요인에 관한 연구 -천안아산생활권 행정협의회를 중심으로-

        강영순 ( Yeong Sun Kang ),하재룡 ( Jai Ryong Ha ) 충남연구원 2021 충남연구 Vol.5 No.1

        본 연구는 지방정부간 협력을 위해 구성한 ‘천안아산생활권 행정협의회’에 대하여 협력 거버넌스의 관점에서 협력성과에 영향을 미치는 요인을 실증적으로 분석하는 데 목적이 있다. 연구를 위하여 Ansell and Gash(2007)의 협력거버넌스 모형을 적용하여 연구모형을 설계하고, 천안시와 아산시의 공무원을 대상으로 실시한 설문조사 자료를 활용하여 분석하였다. 분석 결과, 초기조건의 자원불균형, 상호의존성, 협력경험, 갈등경험 및 제도적 설계의 참여포괄성과 기본규칙, 그리고 시장 리더십, 의회 리더십, 공무원 리더십, 시민리더십이 협력과정에 영향을 미치는 것으로 검증되었다. 협력성과의 재정효율성 향상에는 협력과정의 모든 요인들이 영향을 미치는 것으로 검증되었으며, 행정서비스 향상과 상호신뢰 향상에는 면대면 대화를 제외한 신뢰형성, 과정몰입, 이해공유, 중간결과가 영향을 미치는 것으로 검증되었다. This study aims to empirically analyze factors affecting the collaborative performance in terms of collaborative governance for the 'Cheonan Asan Living Sphere Administrative Council', which was set up for inter-local governmental collaboration. For the research, we used the collaborative governance model of Ansell and Gash (2007) and analyzed data from a survey conducted among public officials of Cheonan and Asan. The analysis confirmed that the resource imbalance, interdependence, cooperation experience, conflict experience of starting conditions, participatory inclusiveness, ground rules in institutional design, as well as mayor leadership, parliament leadership, public official leadership, and civic leadership affect the collaborative process. All factors in the collaborative process were found to affect the improvement of financial efficiency of collaborative performance, and it has been verified that trust building, process commitment, sharing of understanding, and intermediate results, excluding face-to-face dialogue, affect the improvement of administrative services and mutual trust.

      • KCI등재

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