자궁에 발생한 혈관근지방종

배평원(PW Bae),송인철(IC Song),박영주(YJ Park),최근해(GH Choi) 대한산부인과학회 1976 Obstetrics & Gynecology Science Vol.19 No.7

We experienced a cases of Angiomyolipoma of the uterus who was adimtted to our ob and gyn. Department of Obsterics and Gyunecology, the impression of the ovarian tumor of undetermined site. After laparatomy we confirmed the tumor mass was uterine tumor which was reported as angiomyolipoma through pathological examination. The angiomyolipoma is considered as benign mixed mesodermal tumor composed of the various component that is vesseles, muscles fatty tissues, elstic tissues, etc. This tumor has much rare incidence in the uterus but relatively common incidence in the kidney. We present this tumor because of its rarity and interesting pathological entity.

肝吸蟲에 대한 Albendazole의 殺蟲效果에 관한 實驗的 硏究

裵平元,金洙鎭,林漢鍾 고려대학교 의과대학 1984 고려대 의대 잡지 Vol.21 No.3

Newly developed albendazole(zentel®) is a broad spectrum anthelmintic which high activity against intestinal nematodas as well as trematodes and cesstodes infections. The present study was undertaken to evaluato in vitro and in vivo activities of albendazoles against adult worms of clonorchis sinensis. The morphological change of C. sinensis obtained from experimentally infected rats treated with various dosages of albendazole were studied by means of scaning and transmission electron microscope. The results are as follows: 1. The adult worms of C. sinensis were incubated in the medium containing albendazole with various concentrations. By 24 hours after incubation, none of the worms were dead in concentrations of 0.01μg/ml of albendazole. 2. In order to evaluate the effect of albendazole in vivo, experimentally infected rats with 50 metacencariae of C. sinensis each were treated orally with various dosages of albendazole. In the result, anthelmintic effect was confirmed at the dosage of albendazole with 2×25㎎/㎏×2 days (total amounts 100㎎/㎏). 3. Macrocopital examination was to the clonorchis worms which were collected from the bile ducts of the rats autopsied at 24 hours after treatment with albendazole. The lack of intestinal contents was observed in most of worms from the groups treated with 1×200 ㎎/㎏ and 2×25 ㎎/㎏×2 or 4 days, and the elongation of the anterior portion of the worm body was also observed n the worms from the groups treated with 2×25 ㎎/㎏×2 or 4 days. 4. In the scanning electron microscopic observation, many blebs were fromed on the surface of the damaged tegument of the worms at 24 huors after treatment with albendazole(1×200 ㎎/㎏ and 2×25 ㎎/㎏×2 or days). 5. The transmissions electron microscopic observation indicated that degeneration of mitochonriae and destruction of tegumental syncytium of the worms at 24 hours after treatment with albendazole(1×200 ㎎/㎏ and 2×25㎎/㎏ or 4 days). Inaddition to the findings the degeneration of the intestinal lamellae in the caeca was also observed in the worms from the groups treated with same dosages of albendazole.

寶城郡 熊峙面에 있어서의 肺吸蟲症의 疫學的 推移

李駿商,裵平元,林漢鍾,申鴻植 한국농촌보건회 1980 농촌의학·지역보건 Vol.5 No.1

寶城郡 熊峙面에 있어서의 肺吸虫症의 疫學的 推移

李駿商(Joo-Sang Lee),裵平元(Pyung-Weon Bae),林漢鍾(Han-Jong Rim),申鴻植(Hong-Shik Shin) 한국농촌의학 지역보건학회 1980 농촌의학·지역보건 Vol.5 No.1

쌍태임신에 관한 임상적 고찰

김성심(SS Kim),김현찬(HC Kim),배평원(PW Bae),김순애(SA Kim),박영주(YJ Park),박인재(IS Park),박찬무(CM Park) 대한산부인과학회 1975 Obstetrics & Gynecology Science Vol.18 No.5

A clinical review of 239 twin deliveries at National Medical Center for 15 years from 1959 to 1973 was presented . 1. The frequency of twin birth was one in 71 births. 2. The youngest was twenty-one year old woman and the oldest was forty eight year old one in twin delivery, Average age was twenty-nine years. And in primipara 31.8 percent of twin delivery occured. 3. Delivery after 37th week of gestation occured in 76.5% and the babies weighting over 2500 gm. revealed 47.7% . And Apgar socre 7-10 was shown in 88% of the first twin and in 87.0% of the second. 4. In presentation cephalic presentation of the first twin revealed 75.8% and in approximately 70 % of vertex-breech combinations ,the first twin presented by the vertex. 5. Diagnosis of twin pregnancy before labor was made in 71.6% of 239 twin delivery 6. Sponaneous delivery of both babies occurred in 55.6% and operative delivery was performed in 44.4%. 7. Twenty four cases of cesarean section 10.0 % was encounted its main indication being such as repeat cesarean sections, fetal distress secondary inertia and eclampsia. 8. In 15.5% of the cases manual removal of the plaenta was perfomred. 9. About 1% of congenital anomaly was seen 10. Two cases of maternal deaths were encountered.

주산기사망에 대한 임상적고찰

최근해(GH Choi),김서규(SK Kim),배평원(PW Bae) 대한산부인과학회 1974 Obstetrics & Gynecology Science Vol.17 No.2

1) 1968년 1월 1일부터 1972년 12월 말일까지 만 5년간 본원 산과병동에서 분만한 총 7,007 명의 산모로부터 출산된 7,102명의 출산아 중 주산기사망은 278명으로 주산기사망률은 생존 아출산 1,000명에 대하여 39.7에 해당하였다. 2) 주산기사망률은 초산부군에 비하여 2∼5회 경산부군에서 높았고 6회 이상의 다산부군에 서 가장 높았다. 반면 신생아사망률은 2∼5회 경산부군에서, 사망률은 초산부군에서 가장 낮 았고 6회 이상의 다산부군에서는 양자 공히 가장 높았다. 3) 다태임신에서 단태임신에 비하여 주산기사망률이 높았다. 4) 주산기사망의 49.3%가 조산아이었고 50.7%가 성숙아였다. 출산시 체중이 많을수록 주산 기사망률은 감소되었고, 4,000g 이상 군에서는 성숙아군에 비하여 그 사망률이 다소 증가되 었다. 5) 주산기사망 274명 중 65.7%는 산전관호를 받지 않았던 산모로부터, 34.3%는 산전관호를 받았던 산모로부터 출산된 예였다. 6) 태위에 따른 주산기사망률은 둔위분만례에서 172.2로 두위에 비하여 약 6배 높았고 횡위 에서는 564.1로 가장 높았다. 신생아사망은 둔위분만에서 많았고 사산률은 횡위에서 많았다. 7) 분만방법은 총 7,102명에 대하여 자연분만이 72.7%로 가장 많았고, 흡인분만 12.6%, 제와 절개술 8.5%, 인공개조둔위분만 4.5%, 겸자분만 148.9 등의 순이었다. 8) 신생아사망의 시기는 88.3%에서 24시간 이내에 발생하였고 주산기사망의 71.9%가 사산 이었다. 9) 주산기사망의 원인은 저산소증, 임신 중 고혈압증, 이상태위, 선천성기형, 감염 등의 순이 었고 저산소증은 주산기사망예의 29.6%에서 사인으로 간주되었으며 이에 대한 최대 원인은 정상위태반조기박리였다. 임신 중 고혈압증의 빈도는 전 분만예에 대한 24.1%였고 자간증에 서 주산기사망률은 자간전증에 비하여 2.4배 높았다. 그리고 주산기사망 274예 중 임신 중 고혈압증이 원인이라고 생각된 예는 15.7%에 해당하였다. The perinatal mortality has always attracted great interest and this wide interest has been readily explained by the complexity of the biological problems as well as certain definite factors connected with the perinatal period. The present clinical observation of the perinatal mortality at the Obstetric Ward of the National Medical Center, Seoul, during the years of 1968 to 1972, was based upon an obstetrical analysis of all deliveries during this 5 years. During this period there was a total of 6,913 single births with 93 twins and one triplet. Total number of births, therefore, were 7,102 and of these 6,905 were live births. Two hundred and seventy four perinatal deaths occurred throughout the above period. Perinatal mortality comprised all the dead infants with a birth weight above 1,000 gm who had died either before, during labor or in the first 7 days after birth. The results of clinical analysis were summarized as follows : 1. The perinatal mortality rate was 39.7 per 1,000 live births. For the last 2 years the perinatal mortality rate rose about 10 per 1,000 live births mainly due to increase of the neonatal death rate in prematures while the stillbirth rate remained stationary. The early nionatal death rate was 11.2. 2. The perinatal mortality rate was higher in 2 to 5 parity group than in primiparous group and highst in 6 or more. The nionatal death rate was the lowest in 2 to 5 parity group and the highst in 6 or more. 3. The perinatal mortality rate among pleural births were higher than single births. 4. One hundred thirty five babies (49.3%) among 274 perinatal deaths weighted between 1,000∼2,499 g and 139 babies (50.7%) weighed more than 2,500g. There was an inverse relationship between birth weight and mortality rate. 5. Perinatal deaths were more frequent in mothers who had not recieves prenatal care than in mothers who recieved it, even one or more times. 6. The perinatal mortality rate in breech presentation was higher than in cephalic and highst in transverse presentation. In breech presentation the fetuses were more often subject to birth traumas as compaired with ceplalic presentation and the risk of prolapse of the umbilical cord was increased in transverse presentation. Therefore the neonatal death was more frequent breech and the stillbirth rate was highst in transverse presentation. 7. The mode of deliveries were consisted of 72.7% of spontaneous delivery, 12.6% of vacuum extraction, 8.5% of cesarean section, 4.5% of assisted breech delivery, 0.7% of forceps delivery and 1% of moscellaneous modes. The perinatal mortality rate was lowest in the spontaneous delivery group (24.9) and was gradually increased by orders of vacuum extraction 37.6, cesarean section 61.9, assisted breech delivery 77.7 and forceps delivery 148.9. 8. The majority of neonatal deaths occurred within 24 hours after birth (88.3%) and the majority of perinatal deaths occurred during ante or intrapartum (71.9%). 9. The most common cause of perinatal deaths was related to hypoxia (29.6%) of which the most common contributing factor was abruptio placentae. Hypertensive disorders in pregnancy was present in 24.1% of all deliveries with a perinatal mortality rate of 25.5. About half of perinatal deaths were associated with prematurity.

임신중 심장질환의 임상적 고찰 ( 제II보 )

박인서(IS Park),조인제(IJ Cho),배평원(PW Bae),송인철(IC Song),주창남(CN Joo),정규봉(KB Jung),이학중(HJ Lee) 대한산부인과학회 1976 Obstetrics & Gynecology Science Vol.19 No.3

1. The incidence of heart disease in pregnancy was 0.37%. 2. Mitral stenosis was predominated (29.4%) 3. The age distribution was predominated in the age 26-30 (41.1%) 4. Heart disease occurred mainly in the primigravida (32.4%) 5. Functional capacity of the heart was mainly in class I. 6. The chief comlaints were dyspnea, edema and palpitation. 7. Spontaneous vaginal delivery was undertaken in 19 cases (52.8%) and instrumental delivery was in 7 cases (30.5%) 8. The incidence of prematurity was 30.6%. 9. Seventy five percent of cases was complicated among which 30.8% cases was complicated by cardiac failure and 17.3% was complicated by toxemias of pregnancy with heart failure. 10. Digitalization was undertaken in 29 cases (85.3%) 11. No maternal mortality was noted in this study.