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紅疫經過中에 있어서의 Tuberculin Allergy 變動에 關하여
白哲弘,金容彦,徐相夏,琴東爀 中央醫學社 1972 中央醫學 Vol.22 No.2
The author made observations in three baby-homes where the measles prevailed from the beginning of March 1964 to the end of June 1969. Observation was made on 118 infants whose tuberculin reaction had already shown positive (20 -cases naturally converted, 98 cases converted after BCG vaccination). Old tuberculin diluted 2, 000 times, made by the National Institute of Health, was used under the currently widely applied Mantoux intracutaneous method on children during measles to observe the change of tuberculin allergy. The results obtained were as follows: 1) Both children with regular measles and children with measles modified by adult plasma showed decrease of the diameter of the redness 3 to 5 days before the appearance of the rash, and most children from 2 days before and 5 days after appearance the rash showed negative reaction most marked. The decrease in tuberculin allergy was noticed during the eruptive period. No change was specially noticed during the incubation period except for 1 negative case. 2) The length of time elapsing before the tuberculin test turned from negative to positive was an average of 16. 2 days in the group of regular measles and in the group of measles modified by adult plasma, which was intended for passive immunization the time lapse was average of 13 days. Statistically such difference in lapse of time between the two groups was insignificant. 3) In children having measles with pneumonia, the length of time elapsing before the tuberculin test turned from negative to positive averaged 17. 2 days. This means although the case with pneumonia appears longer than the case of measles without pneumonia, there is no significant difference statistically. 4) No significant difference was noticed in the average lengths between the naturally converted case of tuberculin reaction and the positive case turning from negative to positive after BCG vaccination. 5) Repeated tuberculin test every 3 days for 6 weeks produced no case in which the decrease in the tuberculin reaction due to desensitization.
Gargoylism (Hunter’s Syndrome) 1例
白哲弘,鄭秉周,李貴蘭,徐相夏,韓東燮 中央醫學社 1973 中央醫學 Vol.24 No.2
A case of Gargoylism (Hunter's syndrome) studied in regard to genetic pattern, clinical and laboratory finding was inherited as a sex-linked recessive and noticed neither clouding of the cornea nor prominent mental deterioration. The review of literature was made briefly.
白哲弘,全濤基 中央醫學社 1975 中央醫學 Vol.29 No.1
In order to know the yearly variation of antimicrobial susceptibility of Salmonella typhi and to investigate the transferability of resistance by conjugation, 594 str?ains of S. typhi isolated mainly in Taegu area during the period from 1971 through 1974 were subjected for the study. Antimicrobial susceptibility was tested by agar dilution method and the transfer of resistance was studied with Escherichia coli ML 1410 as recipient. Most strains were susceptible to chloramphenicol (CM), tetracycline (TC) and kanamycin (KM) with minimum inhibitory concentration (MIC) of 3.1 ug/ml or -less, and highly susceplible to ampicillin (AP) and trimethoprim-sulfamethoxazole compound (TMP-SMZ, i : 20) with MIC of 1.6pg/ml or less. 'They were slightly resistant to streptomycin (SM) and sulfisomidine (SA) with MIC of 25,ug/ml or less. No marked difference in the antimicrobial spectrum of test strains was noted among strains isolated in 1971 through 1974, only with a slight tendency that strains isolated in 1974 was slightly less susceptible to SM and TMP-SMZ than. those isolated in 1971 through 1973. Small numbers of strains highly resistant to CM, TC, SM, and SA, and other agents were isolated during the years of 1972 through 1974. The resistance of these, strains can be transferred to E. coli ML 1410 by conjugation, but the resistance to polymyxin B and colistin was not transferred. The resistance was transferred at 25 C more easily than at 37 C.
姜相遠,薛盛用,白哲弘,徐正海 中央醫學社 1974 中央醫學 Vol.27 No.3
This study was undertaken to know the influence of temperature on the survival of Vibrio parahaemolyticus (VP) in sea fish homogenates. Homogenates of Octopus dopleini and Raza kenojei in 3% saline were sterilized by steaming, autoclaving and ultraviolet irradiation. The suspensions of VP in homogenates were kept at 4 C and 20 C, and viable cells were counted on BTB teepol agar plates. VP survived for more than 30 days in homogenates at 20 C and sterilized within 10 days at 4 C. Survival of this organism was not different in Oct. dofleini and R. kenojei, but different by the method of sterilizatian of fish homogenate. VP showed longer survival in steamed and UV. Irradiated fish homogenates than autoclaved at 4 C, and grew better in steamed fish homogenate than in autoclaved and UV. Irradiated at 20 C. Survival of this organism in rotted fish homogenate were almost same as compare with fresh fish.
Henoch-Schoenlein증후군에 대한 임상적 관찰
김이우,박성태,백철홍,오지섭,신동학 계명대학교 의과대학 1994 松年 申東鶴 敎授 停年退任紀念 論文集 Vol.1 No.-
The clinical studies of 30 cases of Henoch-Schoenlein syndrome in infancy and children were made. 1) The previous history of the upper respiratory tract infection showed 83.3%. 2) Males were more affected than females. The ratio was approximately 2: 1. 3) In age incidence, the cases were seen mostly from 2 to 8 year(70.0%), especially from 4 to 6 year of Iife(33.3% ). 4) Seasonal incidence was more common in spring 15 cases and fall months 8 cases. 5) Clinical manifestations were skin rash( 100.0%), joint pain(70.0%), abdominaI{63.3%) and nephritis (26.7% ). 6) The most common type of skin rash in Henoch-Schoenlein syndrome was petechiae on the area below the waist, especially buttocks. 7) Joints most often involved were the ankle and knee(85.7%), less frequently the wrists and digits. 8) In gastrointestinal manifestation of Henoch-Schoenlein syndrome, abdominal pain was the most com mon(84.2%) and next gastrointestinal bleeding(78.9%). 9) The renal manifestation of Henoch-Schoenlein syndrome was the most serious sign. Hematuria was more common than albuminuria(75.0%) in these cases. 10) Most cases(28 of 30) were recovered within 6 weeks and one case of nephritis was recovered within 8weeks, but only one case of nephritis was not recovered.