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Prevalence of Multiple Sclerosis in a Turkish City Bordering an Iron and Steel Factory
Ülkü Türk Börü,Adnan Burak Bilgiç,Cansu Köseoğlu Toksoy,Abdullah Yasir Yılmaz,Mustafa Tasdemir,Nilay Padir Sensöz,Özgür Öztop Çakmak,Arda Duman,Cem Bölük 대한신경과학회 2018 Journal of Clinical Neurology Vol.14 No.2
Background and Purpose Multiple sclerosis (MS) is an autoimmune disease characterizedby inflammatory demyelination. Recent studies have shown that long-term exposure to air pollutants(including PM10 particulates) is potentially an environmental risk factor for MS. Weaimed to determine the prevalence rates of MS in two cities with different levels of air pollution. Methods This door-to-door population-based study was conducted between April 2014 andJune 2015. Two cities were screened for the prevalence rates of MS: 1) Karabük, which bordersan iron-and-steel factory, and 2) Akçakoca, which is a coastal city located in the same region. A validated survey form was used for screening MS. The 2010 McDonald Criteria were usedfor diagnosing MS. The patients were examined twice, first by a neurology assistant in the fieldand then by a senior neurologist in public health centers in the cities. Results The prevalence of MS was 95.9/100,000 in Karabük and 46.1/100,000 in Akçakoca. Intotal, 33 patients were diagnosed with clinically definite MS. The female/male ratio was 1.5, and21 patients were diagnosed with relapsing-remitting MS, 9 with secondary progressive MS, and3 with primary progressive MS. Conclusions We found that the prevalence of MS was more than two fold higher in Karabükthan in Akçakoca, which supports a link between air pollution and the pathogenesis of MS. However, larger etiological and epidemiological studies are needed to confirm this hypothesis.
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Headache related to mask use of healthcare workers in COVID-19 pandemic
( Cansu Köseoğlu Toksoy ),( Hayri Demirbaş ),( Erhan Bozkurt ),( Hakan Acar ),( Ülkü Türk Börü ) 대한통증학회 2021 The Korean Journal of Pain Vol.34 No.2
Background: It has been reported that a new type of headache may develop as a result of face mask use during the COVID-19 pandemic. The aim of this study is to investigate the clinical features of face mask-related headache during the COVID-19 pandemic. Methods: This is a cross-sectional study carried out on healthcare workers at the Afyonkarahisar Health Sciences University. The number of workers at our university was established. Sample size was calculated using the G*Power program. A questionnaire consisting of questions relating to pre-existing headache, an aggravation in headache, and de-novo headache was filled out by 3 neurologists with all participants. Results: Data was collected from a total of 375 participants, after the exclusion of 5 individuals who refused to participate. Out of all participants, 26 (6.9%) used a filtering mask, 274 (73.1%) used a surgical mask, 75 (20.0%) participants used a combination of both masks. The number of participants with preexisting headache was 114 (30.4%) had pre-existing headache. Of those with pre-existing headache, 77 (67.5%) healthcare workers had reported an aggravation in their headache after mask use. De-novo headache was observed in 116 (30.9%) of participants. De-novo headache characteristics included throbbing in 17 (14.7%) participants and pressing in 99 (85.3%) participants. In addition, symptoms such as tachypnea, sleep disturbance, and fatigue were found to be significantly higher. Conclusions: This study indicates that healthcare workers develop headaches due to use of masks during the COVID-19 outbreak.
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