Should CAM and CAM Training Programs Be Included in the Curriculum of Schools That Provide Health Education?

Özgür Önal,Deniz Say Sahin,Betül Battaloglu inanc 대한약침학회 2016 Journal of pharmacopuncture Vol.19 No.4

Objectives: This study aimed to determine the knowledge levels and attitudes of School of Health and Vocational School of Health students toward complementary and alternative medicine (CAM). Methods: Three hundred thirty-three (333) students studying at the Mehmet Akif Ersoy University School of Health and the Golhisar Vocational School of Health in Burdur, Turkey, were included in the study. Research data were collected by using a survey method based on the expressed opinions of the participants. Results: Of the participants, 69.7% were female and 97% were single (unmarried). Of cigarette users and those with chronic illnesses, 46.8% and 47.8%, respectively, used CAM. Those using CAM were statistically more likely to be female (P < 0.021), to have higher grades (P < 0.007), to be single (P < 0.005), to be vocational school of health graduates (P < 0.008), and to have fathers at work (P < 0.021). While 9.6% of the students thought CAM to be nonsense, 10.8% thought that the methods of CAM should be tried before consulting a doctor. Conclusion: A majority of the students in the study population were found to use complementary and alternative medicine, but that they lacked information about its methods. As a way to address this, CAM should be included in the curriculum of schools that provide health education, and CAM training programs should be given to healthcare professionals to improve their knowledge of CAM. In Turkey, many more studies should be performed to determine nurses’ and doctors’ knowledge of and attitudes about CAM methods so that they can give correct guidance to society and take more active responsibility in improving patient safety.

Central line-associated bloodstream infections in the intensive care unit: importance of the care bundle

Aynur Atilla,Zahide Doğanay,Hale Kefeli Çelik,Leman Tomak,Özgür Günal,S. Sırrı Kılıç 대한마취통증의학회 2016 Korean Journal of Anesthesiology Vol.69 No.6

Background: The importance and efficacy of a care bundle for preventing central line-associated bloodstream infections (CLABSIs) and infectious complications related to placing a central venous catheter (CVC) in patients in the intensive care unit (ICU). Methods: A care bundle was implemented from July 2013 to June 2014 in a medical ICU and surgical ICU. Data were divided into three periods: the prior period (July 2012–June 2013), the intervention period (July 2013–June 2014; first and second periods), and the post-intervention period (July 2014–December 2014; third period). A care bundle consisting of optimal hand hygiene, skin antisepsis with chlorhexidine (2%) allowing the skin to dry, maximal barrier precautions for inserting a catheter (sterile gloves, gown, mask, and drapes), choice of optimal insertion site, prompt catheter removal, and daily evaluation of the need for the CVC was introduced. Results: The catheterization duration was longer and femoral access was more frequently observed in patients with CLABSIs. CLABSI rates decreased with use of the care bundle. The CLABSI rate in the medical ICU was 6.20/1,000 catheter days during the prior period, 3.88/1,000 catheter days during the intervention period, and 1.05/1,000 catheter days during the third period. The CLABSI rate in the surgical ICU was 8.27/1,000, 4.60/1,000, and 3.73/1,000 catheter days during these three periods, respectively. Conclusions: The choice of an optimal catheter insertion site, use of all barrier precautions, and removal of catheters when they are no longer needed are essential to decrease the CLABSI rate.

Physico-chemical Properties and In vitro Cellular Response of Electrospun Polyurethane Nanofibers Enriched with Copper Chloride and Natural Fish Head Powder

Betül Çelebi-Saltik,Zeynep Haciomeroglu,Didem Kart,Hasan Hüseyin Ünal,Mustafa Özgür Öteyaka 한국섬유공학회 2022 Fibers and polymers Vol.23 No.11

Tissue engineering strategies include successful management of bone injuries with biomaterials to develop bonelikestructures. The production of natural biomaterials for this purpose helps both to ensure tissue integrity and to presentalternative products for clinical purposes. However, natural materials are mostly used together with synthetic or metallicmaterials due to their low stability and mechanical properties for bone tissue regeneration. There is a clinical need formaterial combinations that have both antimicrobial properties and the ability to increase osteogenic induction. This workaims to fabricate a nanofiber scaffold using polyurethane (PU) loaded with natural fish head powder (FHP) fromArgyrosomus regius species and copper (II) chloride (CuCl2) using the electrospinning technique in order to respond to thisclinical need. There has not been any material combination in the literature that contains these compounds, supports bonedifferentiation of stem cells, and prevents bacterial adhesion. To evaluate our composite materials morphology, chemicalstructure, wettability, and thermal analysis were studied with different techniques. Anti-adhesive properties of theStreptococcus mitis (S. mitis) on composite materials were tested with bacterial colonization, and osteogenic inductiveproperties by human bone marrow mesenchymal stem cells (hBMSCs) with and without osteogenic differentiation mediumwere performed with cell viability assay, Alizarin Red staining, Ca deposition and SEM analysis. According to FESEM-EDSand ATR_FTIR data, the additives were highly incorporated into the PU nanofibers. The produced materials had randomlyoriented nanofiber with a porosity of ~72 %. The FHP loaded nanofiber had an average diameter of ~185 nm. The swellingbehavior of FHP-loaded PU roughly decreased for 3, 5, and 7 days due to the hydrophobic character of the sample. Anincreasing percentage of FHP decreased the bacterial colonization of S. mitis. PUn-CuCl2-FHP nanofibers did not exhibit anycytotoxic effect on the hBMSCs. According to Alizarin Red Staining and Ca deposition analysis, stimulation with both thematerial and the osteogenic medium triggered the bone differentiation of the hBMSCs in a combined manner at days-14. Based on the results, it can be deduced that natural fish head is a promising additive material for fabricating bone-likebiomaterials.

Serum Irisin Level Can Predict the Severity of Coronary Artery Disease in Patients with Stable Angina

Tolga Han Efe,Çağrı Yayla,Burak Açar,Göktuğ Ertem,Kadriye Gayretli Yayla,Engin Algül,Sefa Ünal,Murat Bilgin,Tolga Çimen,Özgür Kirbaş,Ekrem Yeter 대한심장학회 2017 Korean Circulation Journal Vol.47 No.1

Background and Objectives: The recently discovered myokine irisin has a proposed role in adipose tissue metabolism. The aim of this study was to evaluate the relationship between serum irisin level and the coronary artery severity in patients with stable coronary artery disease (CAD). Subjects and Methods: Sixty-three patients who underwent coronary angiography (CA) diagnosed with stable CAD and twenty-six patients with normal coronary artery (NCA) were enrolled in the study. Stable CAD patients were divided into two groups as high synergy between percutaneous coronary intervention with taxus and cardiac surgery (SYNTAX) score (≥23) and lower SYNTAX score (<23). Serum irisin level measurement was carried out using human irisin colorimetric enzyme-linked immunosorbent assay (ELISA) commercial kit (AG-45A-0046EK-KI01, Adipogen, San Diego, CA, USA) as recommended by the manufacturer’s protocol. Results: The patients with stable CAD with a higher SYNTAX score (score ≥23) had significantly lower serum irisin levels (127.91±55.38 ng/mL), as compared the patients with a low SYNTAX score (score <23) (224.69±92.99 ng/mL) and control group (299.54±123.20 ng/mL). Irisin levels showed significant differences between all groups (p<0.001). Conclusion: Serum irisin level is an independent predictor of coronary artery severity in patients with stable CAD.