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      • Exercises of Power in Marketing Channel Dyads - Power Advantage versus Power Disadvantage

        Guijun Zhuang,Neil C,Herndon Jr,Nan Zhou 한국마케팅과학회 2005 한국마케팅과학회 학술대회 발표 논문집 Vol.- No.-

        Taking the channel dyad as the unit of analysis, this study investigated the impact of channel members’ power on their uses of power in two distinct conditions: in power advantage and in power disadvantage. The study found that channel members" power has a positive impact on their uses of noncoercive power regardless of their relative position in channel dyads; their uses of coercive power are sensitive negatively to their own power in the condition that they are in power advantage, and sensitive negatively to the target members’ power in the condition that they are in power disadvantage. It also finds that the predictions of deterrence theory are partially supported in both the case of power advantage and power disadvantage, while no evidence supports the predictions of conflict spiral theory in either case. One contribution of this study is that the research method and research findings provide a possible explanation for the inconsistent or contradictory empirical findings on the relationship between power and exercises of power.

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        MEG3 LncRNA from Exosomes Released from Cancer-Associated Fibroblasts Enhances Cisplatin Chemoresistance in SCLC via a MiR-15a-5p/CCNE1 Axis

        Yulu Sun,Guijun Hao,Mengqi Zhuang,Huijuan Lv,Chunhong Liu,Keli Su 연세대학교의과대학 2022 Yonsei medical journal Vol.63 No.3

        Purpose: Long non-coding RNAs (lncRNAs) may act as oncogenes in small-cell lung cancer (SCLC). Exosomes containing lncRNAsreleased from cancer-associated fibroblasts (CAF) accelerate tumorigenesis and confer chemoresistance. This studyaimed to explore the action mechanism of the CAF-derived lncRNA maternally expressed gene 3 (MEG3) on cisplatin (DDP) chemoresistanceand cell processes in SCLC. Materials and Methods: Quantitative real-time PCR was conducted to determine the expression levels of MEG3, miR-15a-5p, andCCNE1. Cell viability and metastasis were measured by 3-(4, 5-dimethyl-2-thiazolyl)-2, 5-diphenyl-2-h-tetrazolium bromide andinvasion assays, respectively. A xenograft tumor model was developed to confirm the effect of MEG3 overexpression on SCLC progressionin vivo. Relationships between miR-15a-5p and MEG3/CCNE1 were predicted using StarBase software and validated bydual luciferase reporter assay. Western blotting was used to determine protein levels. A co-culture model was established to explorethe effects of exosomes on MEG3 expression in SCLC cell lines. Results: MEG3 was overexpressed in SCLC tissues and cells. MEG3 silencing significantly repressed cell viability and metastasis inSCLC. High expression of MEG3 was observed in CAF-derived conditioned medium (CM) and exosomes, and promoted chemoresistanceand cancer progression. Additionally, MEG3 was found to serve as a sponge of miR-15a-5p to mediate CCNE1 expression. Overexpression of miR-15a-5p and knockout of CCNE1 reversed the effects of MEG3 overexpression on cell viability and metastasis. Conclusion: MEG3 lncRNA released from CAF-derived exosomes promotes DDP chemoresistance via regulation of a miR-15a-5p/CCNE1 axis. These findings may provide insight into SCLC therapy.

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        Consumers’ Device Choice in E-Retail: Do Regulatory Focus and Chronotype Matter?

        ( Syed Waqar Haider ),( Zhuang Guijun ),( Amir Ikram ),( Bilal Anwar ) 한국인터넷정보학회 2020 KSII Transactions on Internet and Information Syst Vol.14 No.1

        Today, digital shoppers express increasingly complex buying behavior. They can use multiple channels for shopping and also they can switch from one to another channel almost effortlessly, in the result of engaging in omnichannel shopping behavior. A few years ago, consumers were using brick and mortar stores to make their purchases. However, nowadays, they possess different digital devices (mobile and/or desktop) to search for different alternatives and to make a better shopping choice. These devices (mobile and desktop) are different and offer unique benefits to consumers. However, there has been very little research that has treated mobile and desktop devices separately. Perhaps this study is the pioneer when it comes to investigating the effect of regulatory focus (prevention vs. promotion) and chronotype (morning and evening person) on a sample of university students using desktop and mobile channels for their shopping. The findings from a sample of 312 digital consumers (mobile and/or desktop) confirmed that the desktop channel provides a greater fit for morning-type respondents and that the mobile channel offers better value for evening-type respondents in e-retail. Furthermore, promotion-focused shoppers favor the mobile channel, and prevention-focused shoppers favor the desktop channel. The new insights and contributions of this study provide a better understanding of digital consumers to help sellers to develop a more effective e-retail strategy.

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