A Study on Job Analysis in the Technical Part of Hair Designers

Youngjoo Lee(Youngjoo Lee) J-INSTITUTE 2023 Protection Convergence Vol.8 No.1

Purpose: In modern society, where professional skills and function are required according to changes in the industrial structure, the personal and technical job capabilities of beauty human resources who pursue beauty targeting the human body are the most important factors affecting the growth of beauty companies along with customer satisfaction. Since it is a resource, it is a time when effective and efficient management of human re-sources is desperately needed. introduction of the National Competency Standards and Fair Evaluation Qualifi-cation System, one of the widely used improvement directions to quickly reflect changes in the industrial field, will help improve the productivity of beauty care by studying whether it is correlated with the technical capabili-ties of designers. Method: This survey was conducted for 15 days from August 5, 2022, by setting practitioners nationwide who obtained national qualifications related to hairdressing (hair) and working in hair salons as survey sub-jects, dis-tributed the questionnaires directly, and asked the respondents to fill in the questionnaires directly. An empirical survey was conducted using a self-administered questionnaire survey method. First, a measurement tool was constructed, the factors of the item on the difference in job ability were analyzed, and the validity and reliability of the four factors extracted based on the eigenvalue 1 were tested, and the data were analyzed. Results: As a result of demographic analysis, there were 239 males (50.9%) and 231 females (49.1%), As a result of the descriptive statistics analysis, the overall job competency averaged 3.45 points. Among technical job skills, ‘correction service ability’ (M=3.63) appeared the highest, ‘Cutting skills’ (M=3.62) followed by ‘profes-sional work’ (M=3.52). Differences in technical job competency by gender were relatively higher in men than women in terms of cutting skills, customer hair evaluation/prescription, and more, In the case of women, com-pared to men, permanent wave technology, hair coloring technology, straightening service ability, fashion/inge-nuity, and hair styling skill were relatively higher, showing differences. Technical job skills by age were relatively higher in those in their 50s, 60s, and 20s than those in their 30s and 40s. Job competency according to the final level of education was relatively high in those with a 4-year college degree or higher. It was found that those who majored in beauty related departments had higher work ability than those who did not major. As a result of the analysis by experience, the overall technical job ability was relatively high for less than 5 years or more than 10 years, and for professional work. Conclusion: As a result of analyzing the technical job of hair designers working in the industrial field, it can be seen that those in their 20s have the best technical job ability by age, and those with less than 5 years of experi-ence have the best technical job ability by career. It is recognized that the systematic curriculum of NCS is working meaningfully.

Randomized Phase II Study of Afatinib Plus Simvastatin Versus Afatinib Alone in Previously Treated Patients with Advanced Nonadenocarcinomatous Non-small Cell Lung Cancer

Lee, Youngjoo,Lee, Ki Hyeong,Lee, Geon Kook,Lee, Soo-Hyun,Lim, Kun Young,Joo, Jungnam,Go, Yun Jung,Lee, Jin Soo,Han, Ji-Youn Korean Cancer Association 2017 Cancer Research and Treatment Vol.49 No.4

<P><B>Purpose</B></P><P>This phase II study examined whether the addition of simvastatin to afatinib provides a clinical benefit compared with afatinib monotherapy in previously treated patients with nonadenocarcinomatous non-small cell lung cancer (NA-NSCLC).</P><P><B>Materials and Methods</B></P><P>Patients with advanced NA-NSCLC who progressed after one or two chemotherapy regimens were randomly assigned to a simvastatin (40 mg/day) plus afatinib (40 mg/day) (AS) arm or to an afatinib (A) arm. The primary endpoint was response rate (RR).</P><P><B>Results</B></P><P>Sixty-eight patients were enrolled (36 in the AS arm and 32 in the A arm). The RR was 5.7% (95% confidence interval [CI], 0.7 to 19.2) for AS and 9.4% (95% CI, 2.0 to 25.0) for A (p=0.440). In arms AS and A, the median progression-free survival (PFS) was 1.0 versus 3.6 months (p=0.240) and the overall survival was 10.0 months versus 7.0 months (p=0.930), respectively. Skin rash, stomatitis, and diarrhea were the most common adverse events in both arms. More grade 3 or 4 diarrhea was observed in arm A (18.8% vs. 5.6% in arm AS). In all patients, the median PFS for treatment including afatinib was not correlated with the status of epidermal growth factor receptor (<I>EGFR</I>) mutation (p=0.122), <I>EGFR</I> fluorescence <I>in situ</I> hybridization (p=0.944), or EGFR immunohistochemistry (p=0.976). However, skin rash severity was significantly related to the risk of progression for afatinib (hazard ratio for skin rash grade ≥ 2 vs. grade < 2, 0.44; 95% CI, 0.25 to 0.78; p=0.005).</P><P><B>Conclusion</B></P><P>There were no significant differences in the efficacy between AS and A arms in patients with NA-NSCLC.</P>

Thermal Degradation Kinetics of Antimicrobial Agent, Poly(Hexamethyleneguanidine) Phosphate

Youngjoo Lee,Sangmook Lee,Byung Suk Jin,Jae Wook Lee 한국고분자학회 2006 한국고분자학회 학술대회 연구논문 초록집 Vol.2006 No.10

Modified Aloe Polysaccharide Restores Chronic Stress-Induced Immunosuppression in Mice

Lee, Youngjoo,Im, Sun-A,Kim, Jiyeon,Lee, Sungwon,Kwon, Junghak,Lee, Heetae,Kong, Hyunseok,Song, Youngcheon,Shin, Eunju,Do, Seon-Gil,Lee, Chong-Kil,Kim, Kyungjae MDPI 2016 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.17 No.10

<P>Chronic stress generally experienced in our daily lives; is known to augment disease vulnerability by suppressing the host immune system. In the present study; the effect of modified Aloe polysaccharide (MAP) on chronic stress-induced immunosuppression was studied; this Aloe compound was characterized in our earlier study. Mice were orally administered with MAP for 24 days and exposed to electric foot shock (EFS; duration; 3 min; interval; 10 s; intensity; 2 mA) for 17 days. The stress-related immunosuppression and restorative effect of MAP were then analyzed by measuring various immunological parameters. MAP treatment alleviated lymphoid atrophy and body weight loss. The numbers of lymphocyte subsets were significantly normalized in MAP-treated mice. Oral administration of MAP also restored the proliferative activities of lymphocytes; ovalbumin (OVA)-specific T cell proliferation; antibody production; and the cell killing activity of cytotoxic T lymphocytes. In summary; oral administration of MAP ameliorated chronic EFS stress-induced immunosuppression.</P>

Aloe QDM complex enhances specific cytotoxic T lymphocyte killing <i>in vivo</i> in metabolic disease mice

Lee, Youngjoo,Kim, Jiyeon,An, Jinho,Lee, Heetae,Kong, Hyunseok,Song, Youngcheon,Shin, Eunju,Do, Seon-Gil,Lee, Chong-Kil,Kim, Kyungjae Taylor & Francis 2017 Bioscience, Biotechnology, and Biochemistry Vol. No.

<P>We developed spontaneous diet-induced metabolic disease in mice by feeding them a high-fat diet for 23weeks and administered Aloe QDM complex for 16weeks to examine its restorative effect on immune disorders and metabolic syndrome. A series of immune functional assays indicated Aloe QDM complex enhanced lymphocyte proliferation and antigen-specific immunity as determined by the restored functions of cytotoxic T lymphocytes (CTL) and IgG production. The elevated serum TNF- level was also regulated by Aloe QDM complex treatment, which suggested its complex therapeutic potential. As for metabolic phenotypes, oral administration of Aloe QDM complex significantly improved diabetic symptoms, including high fasting glucose levels and glucose tolerance, and distinctly alleviated lipid accumulation in adipose and hepatic tissue. The simultaneous restoration of Aloe QDM complex on metabolic syndrome and host immune dysfunction, especially on the specific CTL killing was first elucidated in our study.</P>

Impact of EGFR tyrosine kinase inhibitors versus chemotherapy on the development of leptomeningeal metastasis in never smokers with advanced adenocarcinoma of the lung

Lee, Youngjoo,Han, Ji-Youn,Kim, Heung Tae,Yun, Tak,Lee, Geon Kook,Kim, Hyae Young,Lee, Jin Soo Springer-Verlag 2013 Journal of neuro-oncology Vol.115 No.1

Restoration of Declined Immune Responses and Hyperlipidemia by Rubus occidenalis in Diet-Induced Obese Mice

( Youngjoo Lee ),( Jiyeon Kim ),( Jinho An ),( Sungwon Lee ),( Heetae Lee ),( Hyunseok Kong ),( Youngcheon Song ),( Hye Ran Choi ),( Ji-wung Kwon ),( Daekeun Shin ),( Chong-kil Lee ),( Kyungjae Kim ) 한국응용약물학회 2017 Biomolecules & Therapeutics(구 응용약물학회지) Vol.25 No.2

Hyperlipidemia, which is closely associated with a fatty diet and aging, is commonly observed in the western and aged society. Therefore, a novel therapeutic approach for this disease is critical, and an immunological view has been suggested as a novel strategy, because hyperlipidemia is closely associated with inflammation and immune dysfunction. In this study, the effects of an aqueous extract of Rubus occidentalis (RO) in obese mice were investigated using immunological indexes. The mice were fed a high-fat diet (HFD) to induce hyperlipidemia, which was confirmed by biochemical analysis and examination of the mouse physiology. Two different doses of RO and rosuvastatin, a cholesterol synthesis inhibitor used as a control, were orally administered. Disturbances in immune cellularity as well as lymphocyte proliferation and cytokine production were significantly normalized by oral administration of RO, which also decreased the elevated serum tumor necrosis factor (TNF)-α level and total cholesterol. The specific immune-related actions of RO comprised considerable improvement in cytotoxic T cell killing functions and regulation of antibody production to within the normal range. The immunological evidence confirms the significant cholesterol-lowering effect of RO, suggesting its potential as a novel therapeutic agent for hyperlipidemia and associated immune decline.

Acquisition of Face Image using Face Detection and PTZ - Function

YoungJoo Lee,JongShill Lee,SangMin Lee,EungHyuk Lee,HongKi Min,SeungHong Hong 대한전자공학회 2004 ITC-CSCC :International Technical Conference on Ci Vol.2004 No.7

The clinical impact of family history of cancer in female never-smoker lung adenocarcinoma

Lee, Youngjoo,Jeon, Jae Hyun,Goh, Sung-Ho,Roh, Hanseong,Yun, Ji-Young,Kwon, Nak-Jung,Choi, Jin Ho,Yang, Hee Chul,Kim, Moon Soo,Lee, Jong Mog,Lee, Geon Kook,Han, Ji-Youn Elsevier 2019 Lung cancer Vol.136 No.-

<P><B>Abstract</B></P> <P><B>Objectives</B></P> <P>Accumulating evidence reveals the association between the risk of never-smoker lung cancer and family history of cancer. However, the clinicogenomic effect of family history of cancer in never-smoker lung cancer remains unknown.</P> <P><B>Material and methods</B></P> <P>We screened 3,241 lung cancer patients who (a) underwent curative resection at National Cancer Center (Goyang, Korea) between 2001–2014, and (b) completed a pre-designed interview about family/smoking history at the time of diagnosis and identified 604 female never smoker lung adenocarcinoma. A positive family history of cancer [categorized as pulmonary cancer (FH-PC) or non-pulmonary cancer (FH-NPC)] was defined as a self-reported history of cancer in first-degree relatives. Survival data were followed up until January 2017. Multiplexed targeted next-generation sequencing was performed for genetic profiling.</P> <P><B>Results</B></P> <P>Of 604 patients, 29.1% (n = 176) had a FH, including 132 (21.9%) with FH-NPC and 44 (7.3%) with FH-PC. Patients with the FH-NPC had a higher proportion of young patients (≤45 years) than those without the FH-NPC (FH-NPC, FH-PC, and no FH; 13.6%, 2.3%, and 8.2%, respectively; <I>P</I> = 0.032). Patients with the FH-NPC had an increased risk of recurrence (hazard ratio [HR]: 1.90; 95% confidence interval [CI]: 1.40–2.56; <I>P<</I>0.001) and death (HR: 1.67; 95% CI: 1.18–2.37; <I>P=</I>0.004). In contrast, the FH-PC had no prognostic effect on recurrence (HR: 1.23; 95% CI: 0.71–2.15; <I>P = 0.456</I>) and death (HR: 0.93; 95% CI: 0.45–1.91; <I>P=</I>0.838). Among three driver oncogene alterations, <I>EGFR</I> mutation was significantly associated with the FH-PC (53.8%, 84.1%, and 65.8%, respectively; <I>P</I> = 0.016), <I>ALK</I>/<I>ROS1</I>/<I>RET</I> fusions was significantly associated with the FH-NPC (13.7%, 0.0%, and 5.0%, respectively; <I>P</I> = 0.004), but <I>KRAS</I> mutation was not associated with any type of the FH (13.8% vs. 6.0% vs. 7.8%, respectively; <I>P</I> = 0.288).</P> <P><B>Conclusion</B></P> <P>The type of family history of cancer was associated with distinct clinocogenomic subtypes and prognosis of never-smoker lung adenocarcinoma.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Family history of cancer is related to distinct subtypes of never smoker lung cancer. </LI> <LI> <I>ALK/ROS1/RET</I> fusions are enriched in patients with family history of nonlung cancer. </LI> <LI> <I>EGFR</I> mutations are enriched in patients with family history of lung cancer. </LI> <LI> Family history of nonlung cancer is associated with poor prognosis after operation. </LI> </UL> </P>

Restoration of Declined Immune Responses and Hyperlipidemia by Rubus occidenalis in Diet-Induced Obese Mice

Lee, Youngjoo,Kim, Jiyeon,An, Jinho,Lee, Sungwon,Lee, Heetae,Kong, Hyunseok,Song, Youngcheon,Choi, Hye Ran,Kwon, Ji-Wung,Shin, Daekeun,Lee, Chong-Kil,Kim, Kyungjae The Korean Society of Applied Pharmacology 2017 Biomolecules & Therapeutics(구 응용약물학회지) Vol.25 No.2

Hyperlipidemia, which is closely associated with a fatty diet and aging, is commonly observed in the western and aged society. Therefore, a novel therapeutic approach for this disease is critical, and an immunological view has been suggested as a novel strategy, because hyperlipidemia is closely associated with inflammation and immune dysfunction. In this study, the effects of an aqueous extract of Rubus occidentalis (RO) in obese mice were investigated using immunological indexes. The mice were fed a high-fat diet (HFD) to induce hyperlipidemia, which was confirmed by biochemical analysis and examination of the mouse physiology. Two different doses of RO and rosuvastatin, a cholesterol synthesis inhibitor used as a control, were orally administered. Disturbances in immune cellularity as well as lymphocyte proliferation and cytokine production were significantly normalized by oral administration of RO, which also decreased the elevated serum tumor necrosis factor $(TNF)-{\alpha}$ level and total cholesterol. The specific immune-related actions of RO comprised considerable improvement in cytotoxic T cell killing functions and regulation of antibody production to within the normal range. The immunological evidence confirms the significant cholesterol-lowering effect of RO, suggesting its potential as a novel therapeutic agent for hyperlipidemia and associated immune decline.