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      • The Acquisition of Functional Categories: Data from Japanese

        ( Yoshie Yamashita ) 한국언어정보학회 1998 국제 워크샵 Vol.1998 No.-

        While demonstratives and other determiner-like words in English are part of the functional system, their Japanese counterparts are simple lexical categories. The semantic theory (e.g. Brown & Fraser 1963) predicts that these elements must emerge at a later stage in both languages since they denote relatively abstract and complex meanings; whereas Radford`s(1990) maturational theory makes no such predictions about Japanese. In replicating O`` Grady`s (1993) Korean study, I collected both production and comprehension data for Japanese. The data indicates that despite their categorial status (i.e. lexical categories), these determiner-like elements emerge quite late. Since the late emergence of these elements in both Japanese and English can be attributed to their relatively abstract semantics, there is no reason to attribute the late acquisition of English determiners to their categorial status (i.e. functional categories). Thus, just like O``Grady`s Korean data, the Japanese data seems to support the semantic theory.

      • Influence of Isoflavone Intake and Equol-producing Intestinal Flora on Prostate Cancer Risk

        Sugiyama, Yukiko,Masumori, Naoya,Fukuta, Fumimasa,Yoneta, Akihiro,Hida, Tokimasa,Yamashita, Toshiharu,Minatoya, Machiko,Nagata, Yoshie,Mori, Mitsuru,Tsuji, Hirokazu,Akaza, Hideyuki,Tsukamoto, Taiji Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1

        Background: The age-adjusted incidence rate of prostate cancer (PCa) has been reported to be lower among Asians than Western populations. A traditional Japanese meal, high in soybean products or isoflavones, may be associated with a decreased risk of PCa. Equol, which is converted from daidzein by human intestinal flora, is biologically more active than any other isoflavone aglycone. Materials and Methods: We reviewed not only recent epidemiological studies on association of isoflavones with PCa risk, but also recent research on human intestinal bacteria responsible for converting daidzein into equol. Studies were systematically searched from the database published within the last 5 years of from 2008-2012. Results: Five out of 6 articles showed significant association of isoflavones with a decreased risk of PCa, and two of them consistently showed that equol-producers carry a significantly reduced risk of PCa. Furthermore, 5 human intestinal bacteria that can convert daidzein into equol were identified in the last 5 years. Conclusions: If equol can reduce risk of PCa, a possible strategy for reducing the risk of PCa may be to increase the proportion of equol-producers by changing the intestinal flora to carrying an equol-producing bacterium with dietary alteration or probiotic technology.

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