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문인성,박장상,고용복,김용귀,홍성곤,김승남 대한혈관외과학회 1999 Vascular Specialist International Vol.15 No.1
The early diagnosis of abdominal aortic aneurysms are difficult, especially when they are not clinically evident. Because of the generalized nature of atherosclerosis, there is reason to believe that there is a high incidence of aneurysms of the abdominal aorta in patients with peripheral vascular disease. But the screening test for hidden abdominal aortic aneurysms in patients with peripheral arterial disease has not been used for routine manner. So we retrospectively reviewed the 9 patients who had asymptomatic abdominal aortic aneurysms with symptomatic peripheral arterial disease during the last four and half-year period: among them three aneurysms were screened preoperatively by physical examination with their diameter more than 5 cm and 6 aneurysms were found intraoperatively with their mean diameter of 3.8cm. The ages ranged from 66 through 84 years with the mean age 73 years. There were 7 men and 2 women. The sites of the peripheral occlusive disease is as follows: femoral artery only in 1, iliac artery only in 2, both iliac and femoral arteries in 5, and from iliac artery through tibial artery with thrombus formation in 1. We suggest that ultrasonographic screening for the presence of hidden abdominal aortic aneurysm preoperatively in patients with lower extremity occlusive arterial disease is needed, especially when the ages of patients is older than 65 years and the site of arterial disease include iliac segment.
중국, 한국, 조선족 중고등학생의 학교따돌림 피해실태에 대한 비교연구
최미경,김광일,박용천,이동근,고복자 關東大學校 醫科大學 醫科學硏究所 2004 關東醫大學術誌 Vol.8 No.2
This study was attempted to compare the aspects of victims including incidence rate of bullying victims, type of bullying and period and place of bullying for the past one year among Chinese, Korean and Korean-Chinese juveniles of 605, 683 and 617, respectively. Investigation with the self-administered questionnaire was conducted, which was for Korean, Chinese and Korean-Chinese junior high and high school students(12 schools in total of each 2 junior high schools and each 2 high schools) in Seoul and Yanbian between Oct. 2001 and Mar. 2002. Findings of this study are as follows: The definite characteristics of Korean victims were found: Generally, they showed low incidence rate of bullying victims but they showed more "alienated follower type" bullying, more period and frequency of bullying, and more collective bullying than Chinese and Korean-Chinese students. Also, they showed more severe psychological pain and lethargy - a state of sluggishness when other students are bullied - compared to Chinese and Korean-Chinese students. The other side, most of Korean-Chinese victims replied "They wanted revenge" as a feeling after being bullied like Korean victims but significant numbers of them replied "They endured" as a coping method, suggesting their psychological pain. On the other hand, Korean-Chinese students showed more bullying victims "outside the school" than Korean and Chinese students, suggesting difficulty in intervention. It is concluded that comparative studies on individual conditions and cultural characteristics of the victims are further needed in order to make the above-mentioned differences clear.
문인성,박장상,김용귀,문석일,고용복 대한혈관외과학회 1998 Vascular Specialist International Vol.14 No.2
Iliac vein compression syndrome is a rare clinical condition in which left common iliac vein is anatomically compressed between right common iliac artery and the fifth lumbar vertebrae or pelvic brim. Patients usually have marked edema of the left leg. Although the actual incidence is unknown, this syndrome most affects women in the second to fourth decade of life. We report 4 cases of iliac compression syndrome treated by surgical intervention during the last fifteen-year period. Among them, two women have suffered from chronic intermittent swelling and pain of left leg, and two men had acute or subacute symptoms. The fibrous web in the entrance of left iliac vein into vena cava existed in one case. Including this one, two were treated by transposition of iliac artery or vein with thrombectomy. One was decompressed the arterial compression by mobilization or adhesiolysis of the surrounding vessles with thrombectomy. To the last one in which the distal common iliac vein was compressed by tortous dilated left internal iliac artery, transsection and ligation of the internal iliac artery was performed. All patients have experienced improved left leg condition after operation. except the last one in which suffered from thrombosis of left popliteal vein after the iliac decompression.
Effects of Prostaglandin E₁ on Rat Cardiac Allografts with Cyclosporin
Koh, Yong Bok CATHOLIC MEDICAL CENTER 1993 Bulletin of the Clinical Research Institute Vol.21 No.2
Organ allograft rejection is charcterized by cellular infiltration, reduction in blood flow arid intravascular coagulation, resulting out graft organ failure. The absolute increase in thromboxane and relative decrease in prostacyclin synthesis in allograft is suspected the basic phoneme- non in prostacyclin-thromboxane system in acute rejection (1-3). Recently ti has been suggested that the reduction in renal blood flow in cyclosporin (CyA)-induced nephrotoxicity seems to be due to inhibited endothelial production of prostncyclin (PGI_2) by CyA.^4 Several animal experiments reported that prostaglandin bought prolongation of allograt survival(5, 6). The present study was undertaken to investigate the effects of exogenous prostaglandin E, (analogue of PGI_2) upon rat cardiac allografts under CyA therapy.
Effects of Overdose Cyclosporin A upon Function and Structure of Rat Kidneys and Renal Allograft
Koh, Yong Bok,Kim, Dong Goo,Lee, Yong Kak CATHOLIC MEDICAL CENTER 1985 Bulletin of the Clinical Research Institute Vol.13 No.1
The potentially valuable immunosuppressant cyclosporin A, which exerts a selective inhibitory effect on antigen-reactive T-cells (1), causes a number of adverse effects in human including nephrotoxicity. The purpose of this study is to investigate the nephrotoxicity in normal kidney and transplanted kidney in rats when overdose CsA (25 mg/kg/day) was administrated by oral route. The experimental rats were divided into non-renal transplant and renal transplanted groups. Non-renal transplant groups were subdivided into CsA continuous fed group, CsA dose decreasing group, CsA withdrawal group. Transplantation groups were subdivided into transplantation with CsA treatment and trunsplantation without CsA treatment. Studies consist of weekly determination of CsA serum level, serum BUN, crentinine and urinary N-acetyl-β-D-glucosaminidase (NAG) and structural changes of kidney by light microscope and electron microscope. The experimental results were as follows: 1. Serum BUN, creatinine, urinary NAG and the degree of structural abnormality were changed proportionally to CsA serum level. 2. Typical structural changes consisted of tubular vacuolization, intracytoplasmic inclusion body, and interstitial fibrosis but glomerular arteriolar changes were not examined. 3. Renal transplants with CsA treatment remained functioning for 4 weeks. Function and structural change of transplant kidney was more severe than CsA continuous fed group.
Comparative Observations of Peritonitis Induced by Bile, Urine, Pancreatic and Gastric Juice
Koh, Yong Bok,Seo, Kyung Ho,Yoo, Seung Jin,Lee, Yong Kak CATHOLIC MEDICAL CENTER 1987 Bulletin of the Clinical Research Institute Vol.15 No.1
Peritonitis develops whenever irritant materials gain entry into the peritoneal cavity with rupture of abdominal viscus. The soilage is initially sterile, but chemical peritonitis due to peritoneal insult occurs with translocation of plasma into peritoneal cavity. Sooner or later bacterial invasion commonly happens and sepsis ensues if appropriate treatment is not performed. This experiment was attempted to investigate the pathophysiological events in peritonitis in rats. The experimental animals were divided into 4 groups according to the methods of experimental peritonitis: bile, urine, pancreatic and gastric juice peritonitis group. Each group consisted of 10 rats. 1. Seven, 6, 5 and 2 rats in bile, urine, pancreatic and gastric juice peritonitis group, respectively, died during 48 hours. 2. The values of hematocrit in each experimental groups increased gradually with the lapse of time, suggestive of hemoconccntration secondary to plasma loss. The increasing pattern of hemoconcentration secondary to plasma loss. The increasing pattern of hematocrit was most apparent in bile peritonitis group. 3. White blood cell counts in each experimental groups also increased with the lapse of time. This finding was most significant in bile peritonitis group. 4. Plasma protein and albumin level decreased gradually, but there was no significant difference between 3 experimental groups in liver bile peritonitis group. 5. Marked pathological changes were observed in liver and lung. Parcnchymal necrosis, fibrino-supprative change, sinusoidal congestion and thrombus formation were main findings observed in liver. Interstitial edema, hemorrhage, thrombus formation and acute supprative changes were the prominent findings in lung. It was found that liver was the organ which was insulted most extensively from advanced peritonitis.