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- 저자 : ( Thuy Huong Truong ) (검색결과 4 건)
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Tourism Service Encounter in the Cross-Cultural Context
Thuy-Huong Truong 세계문화관광학회 2020 International Journal of Culture and tourism Resea Vol.13 No.1
This paper explores the respective rules of behaviour of international tourists from China, France and the USA and Vietnamese service providers. The Principal Components Analysis method is used to identify and group the distinctive rules of behaviour of tourists and hosts with a view to providing an enhanced understanding of tourists-hosts interaction during the service encounter in cross-cultural settings. It presents the findings of a self-administered survey to 235 Chinese, 180 French and 170 American tourists visiting Vietnam. The rules of behaviour guiding Western and Asian respondents were found to have more differences than similarities. The differences impact upon host and guest intercultural interactions during service encounter. The research has both practical and academic significance. From the theoretical perspective, this study provides an enhancing understanding of Argyle et al.’s study on cross-cultural variations in the rules which determine relationships. This instrument has previously been applied in the field of sociology, psychology and marketing. In the present case, it is used with some modifications to measure hosts-guests cross-cultural interactions in the service encounter and the associated insights should be useful for tourism researchers. The implications for tourism industry management destination and marketers are presented. It is recommended that the Vietnamese tourism authorities target international tourism markets more precisely and improve the quality of service provision.
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In the Cross-Cultural Context of Vietnam
( Thuy Huong Truong ) 한국문화관광학회 2014 문화관광연구 Vol.16 No.2
This paper explores the respective rules of behaviour of international tourists from China, France and the USA and Vietnamese service providers. The Principal Components Analysis method is used to identify and group the distinctive rules of behaviour of tourists and hosts with a view to providing an enhanced understanding of tourists-hosts interaction during the service encounter in cross-cultural settings. It presents the findings of a self-administered survey to 235 Chinese, 180 French and 170 American tourists visiting Vietnam. The rules of behaviour guiding Western and Asian respondents were found to have more differences than similarities. The differences impact upon host and guest inter-cultural interactions during service encounter. The research has both practical and academic significance. From the theoretical perspective, this study provides anenhancing understanding of Argyle et al.’s study on cross-cultural variations in the rules which determine relationships. This instrument has previously been applied in the field of sociology, psychology and marketing. In the present case, it is used with some modifications to measure hosts-guests cross-cultural interactions in the service encounter and the associated insights should be useful for tourism researchers. The implications for tourism industry management destination and marketers are presented. It is recommended that the Vietnamese tourism authorities target international tourism markets more precisely and improve the quality of service provision.
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Panaxynol, a natural Hsp90 inhibitor, effectively targets both lung cancer stem and non-stem cells
Le, Huong Thuy,Nguyen, Huy Truong,Min, Hye-Young,Hyun, Seung Yeob,Kwon, Soonbum,Lee, Yeongcheol,Le, Thi Hong Van,Lee, Jeeyeon,Park, Jeong Hill,Lee, Ho-Young Elsevier 2018 Cancer letters Vol.412 No.-
<P><B>Abstract</B></P> <P>Cancer stem-like cells (CSCs) contribute to tumor recurrence and chemoresistance. Hence, strategies targeting CSCs are crucial for effective anticancer therapies. Here, we demonstrate the capacities of the non-saponin fraction of <I>Panax ginseng</I> and its active principle panaxynol to inhibit Hsp90 function and viability of both non-CSC and CSC populations of NSCLC <I>in vitro</I> and <I>in vivo.</I> Panaxynol inhibited the sphere forming ability of NSCLC CSCs at nanomolar concentrations, and micromolar concentrations of panaxynol suppressed the viability of NSCLC cells (non-CSCs) and their sublines carrying acquired chemoresistance with minimal effect on normal cells derived from various organs. Orally administered panaxynol significantly reduced lung tumorigenesis in <I>Kras</I> <SUP> <I>G12D/+</I> </SUP> transgenic mice and mice carrying NSCLC xenografts without detectable toxicity. Mechanistically, panaxynol disrupted Hsp90 function by binding to the N-terminal and C-terminal ATP-binding pockets of Hsp90 without increasing Hsp70 expression. These data suggest the potential of panaxynol as a natural Hsp90 inhibitor targeting both the N-terminal and C-terminal of Hsp90 with limited toxicities.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Panaxynol inhibited the sphere-forming ability of NSCLC CSCs by inducing apoptosis. </LI> <LI> Panaxynol suppressed the viability of NSCLC cells with no effects on normal cells. </LI> <LI> Panaxynol significantly reduced lung tumorigenesis without detectable toxicity. </LI> <LI> Panaxynol interacted with the N- and C-terminal ATP binding pockets of Hsp90. </LI> <LI> Panaxynol disrupted Hsp90 function without inducing Hsp70 expression. </LI> </UL> </P>
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