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( Ganis Irawan ),( Wira Idiawaty ),( Teuku Mamfaluti ),( Mahriani Sylvawani ),( Fauzi Yusuf ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) is a disorder associated with various drugs and characterized by cutaneous drug eruption, eosinophilia and systemic symptoms. The diagnosis poses diffi culties due to its heterogeneity and long latency period. We report a case of 25 year old male with medical history significant for stage four chronic kidney disease, recently started on allopurinol for hyperuricemia, presented with fever, generalized exfoliative dermatitis and jaundice. Laboratory examination revealed hypereosinophilia, hyperuricemia, elevated bilirubin and elevated liver enzymes. Magnetic resonance imaging revealed acalculous cholecysititis and gallbladder hydrops. He was successfully treated with oral methylprednisolone and bepotastine.