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Han, Sun Woong,Lee, Keun Ho,Yoo, Young Bum,Park, Jee Ho,Song, Kie Moon,Baik, Hong Koo Institute of Pure and Applied Physics 2016 Japanese Journal of Applied Physics Vol. No.
<P>In this paper, solution-based deposition of HfO2 thin film at low temperature was demonstrated. By using aqueous HfCl4 solution, the precursor was effectively decomposed with low annealing temperature of 150 degrees C. Thus it is preferable to use this solution for dielectric coating on flexible substrates. To achieve conformal coating on substrate, formic acid as a cosolvent was added to aqueous ink solution to reduce surface tension of the solution. Due to improved coating quality of HfO2 thin film, the fabricated HfO2 gate dielectric shows reliable breakdown characteristics and low leakage current. (C) 2016 The Japan Society of Applied Physics</P>
한기웅(Ki-Woong Han),김상호(Sang-Ho Kim),이석재(Seok-Jae Lee),이순흠(Sun-heum Lee),안달(Dal Ahn),한상민(Sang-Min Han) 한국정보기술학회 2012 Proceedings of KIIT Conference Vol.2012 No.11
본 논문에서는 다중공진기와 UWB 안테나를 이용한 Chipless Tag와 리더기를 이용하여 근거리 무선통신이 가능한 시스템을 제안하였다. spiral 공진기로 7 bit를 표시하는 다중공진기를 만들었으며 UWB 안테나는 사각패치를 이용한 모노폴 안테나로 제작하였다. 흡수체 사이에 Chipless Tag와 두 개의 리더기 안테나를 지지대에 고정시킨 후 네트워크 분석기로 다중공진을 측정 하였다. Chipless RFID 시스템의 공진 주파수 측정 결과와 다중공진기의 공진 주파수 측정결과가 동일한 특성을 갖는 것을 확인할 수 있었다. In this paper, Chipless Tag and reader using multi-resonator and UWB antenna using a short-range wireless communications system is proposed. Created 7bit to display multi-spiral resonators and resonator and UWB monopole antenna with rectangular patch antenna was fabricated. Chipless Tag and two reader antenna between the absorber was fixed to support multi-resonant network analyzer were measured. Measured resonant frequency of Chipless RFID system could confirm the results and the multi-resonant frequency of the resonator, the measurement results with the same characteristics.
Son, Gi Hoon,Chung, Sooyoung,Choe, Han Kyoung,Kim, Hee-Dae,Baik, Sun-Mee,Lee, Hankyu,Lee, Han-Woong,Choi, Sukwoo,Sun, Woong,Kim, Hyun,Cho, Sehyung,Lee, Kun Ho,Kim, Kyungjin National Academy of Sciences 2008 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.105 No.52
<P>Glucocorticoid (GC) is an adrenal steroid with diverse physiological effects. It undergoes a robust daily oscillation, which has been thought to be driven by the master circadian clock in the suprachiasmatic nucleus of the hypothalamus via the hypothalamus-pituitary-adrenal axis. However, we show that the adrenal gland has its own clock and that the peripheral clockwork is tightly linked to steroidogenesis by the steroidogenic acute regulatory protein. Examination of mice with adrenal-specific knockdown of the canonical clock protein BMAL1 reveals that the adrenal clock machinery is required for circadian GC production. Furthermore, behavioral rhythmicity is drastically affected in these animals, together with altered expression of Period1, but not Period2, in several peripheral organs. We conclude that the adrenal peripheral clock plays an essential role in harmonizing the mammalian circadian timing system by generating a robust circadian GC rhythm.</P>
Kim, Hongbeom,Yoon, Yoo-Seok,Han, Youngmin,Kwon, Wooil,Kim, Sun-Whe,Han, Ho-Seong,Yoon, Dong-Sup,Park, Joon Seong,Park, Sang-Jae,Han, Sung-Sik,Lee, Seung Eun,Choi, Seong Ho,Han, In Woong,Kim, Eunjung Elsevier 2020 Clinical gastroenterology and hepatology Vol.18 No.4
<P><B>Background & Aims</B></P> <P>We studied the effects of pancreatic enzyme replacement therapy (PERT) on body weight, nutritional status, and quality of life (QoL) in patients with pancreatic exocrine insufficiency after pancreatoduodenectomy.</P> <P><B>Methods</B></P> <P>We performed a randomized, double-blind trial of 304 patients who underwent pancreatoduodenectomy at 7 tertiary referral hospitals in South Korea. Patients with fecal levels of elastase of 200 μg/g or less, before and after surgery, were assigned randomly to groups that received PERT (a single capsule of 40,000 IU pancreatin, Norzyme (40,000 IU, Pankreatan; Nordmark Arzneimittel GmbH & Co, Uetersen, Germany), 3 times each day during meals for 3 months; n = 151) or placebo (n = 153). Protocol completion was defined as taking more than two thirds of the total dose without taking other digestive enzymes; the protocol was completed by 71 patients in the PERT group and 93 patients in the placebo group. Patients underwent a physical examination, oral glucose tolerance tests, and blood tests at baseline and at month 3 of the study period. The primary end point was change in body weight. Secondary end points were changes in bowel habits, nutritional parameters, and QoL.</P> <P><B>Results</B></P> <P>In the per-protocol analysis, 3 months after the study began, patients in the PERT group gained a mean of 1.09 kg in weight and patients in the placebo group lost a mean of 2.28 kg (difference between groups, 3.37 kg; <I>P</I> < .001). However, no difference in body weight was observed between groups in the intent-to-treat analysis. Three months after the study began, the mean serum levels of prealbumin increased by 10.9 mg/dL in the PERT group and increased by 7.8 mg/dL in the placebo group (<I>P</I> = .002). Poor compliance to PERT was a significant risk factor for weight loss (<I>P</I> < .001). There was no significant difference in QoL scores between groups.</P> <P><B>Conclusions</B></P> <P>In the intent-to-treat analysis of data from a randomized trial, we found no significant effect of PERT on mean body weights of patients with pancreatic exocrine insufficiency after pancreatoduodenectomy. However, with active education and monitoring, PERT could increase body weight and nutritional parameters. ClinicalTrials.gov no: NCT02127021.</P>
Han, In Woong,Jang, Jin-Young,Lee, Kyoung Bun,Kang, Mee Joo,Kwon, Wooil,Park, Jae Woo,Chang, Ye Rim,Kim, Sun-Whe Elsevier 2014 HPB Vol.16 No.6
<P>The fate of a microscopic positive ductal margin (MPDM) of extrahepatic bile duct (EHBD) cancer is unclear. The purpose of this study was to analyse the clinicopathological features of EHBD cancer with MPDM and to identify the prognostic factors associated with survival.</P>