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RISS 인기검색어
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- 저자 : ( Sabrina Hayati ) (검색결과 2 건)
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Synthesis and Characterization of Gold Nanostars with Different Method
( Sabrina Hayati ),이혜진 한국공업화학회 2016 한국공업화학회 연구논문 초록집 Vol.2016 No.1
Gold nanparticles receive particular interest due to their unique properties and application. The shape and crystallographic facets are the major factors in determining the catalytic and surface activity of metal nanoparticles and the size can influence the optical properties of metal nanoparticles. This work investigates gold nanoparticles star-shaped synthesis with two different method; surfactant-capped and free-surfactant synthesis to increase yield, homogeneous distribution, and small size of nanostars. High-yield and monodispersity of nanostars obtain from free-surfactant synthesis method. The small core size of nanostars and multiple long thin branches also presented by this method.
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Role of co-expression of estrogen receptor beta and Ki67 in prostate adenocarcinoma
Nornazirah Azizan,Firdaus Hayati,Nur Maya Sabrina Tizen,Wirda Indah Farouk,Noraidah Masir 대한비뇨의학회 2018 Investigative and Clinical Urology Vol.59 No.4
Purpose: To evaluate the expression of estrogen receptor (ER)-beta and Ki67 in prostate cancer and study their relationship. Materials and Methods: We analyzed 101 cases of prostate adenocarcinoma diagnosed from January 2011 to June 2015 in 100 patients. Immunohistochemical staining of ER-beta and Ki67 was analyzed according to Gleason score categorized into prognostic groups of 1 to 5. Double-immunofluorescent staining of ER-beta and Ki67 was performed in a total of 20 cases to study the co-expression and the relationship between these markers within the same tumor. Results: A total of 53 of 101 cases (52.5%) were positive for ER-beta expression. There was a positive correlation whereby a high percentage of ER-beta expression was seen in the higher prognostic groups (groups 4 and 5; p=0.007). High Ki67 expression was observed in the higher prognostic group, whereas low Ki67 or negative expression was found in the lower prognostic group (p<0.001). The majority of cases evaluated with double-immunofluorescent staining (14/20) showed co-expression of ER-beta and Ki67 at the individual cell level. Conclusions: ER-beta and Ki67 are independent tumor markers in high prognostic groups. Hence, co-expression of ER-beta and Ki67 indicates a more aggressive tumor with a poorer prognosis.
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