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Practical Circuits with Physarum Wires
James GH Whiting,Richard Mayne,Nadine Moody,Ben de Lacy Costello,Andrew Adamatzky 대한의용생체공학회 2016 Biomedical Engineering Letters (BMEL) Vol.6 No.2
Purpose Protoplasmic tubes of Physarum polycephalum,also know as Physarum Wires (PW), have been previouslysuggested as novel bio-electronic components. Until recently,practical examples of electronic circuits using PWs have beenlimited. These PWs have been shown to be self repairing,offering significant advantage over traditional electroniccomponents. This article documents work performed toproduce practical circuits using PWs. Methods We have demonstrated through manufacture andtesting of hybrid circuits that PWs can be used to produce avariety of practical electronic circuits. A plurality of differentapplications of PWs have been tested to show the universalityof PWs in analogue and digital electronics. Results Voltage dividers can be produced using a pair ofPWs in series with an output voltage accurate to within 12%. PWs can also transmit analogue and digital data with afrequency of up to 19 kHz, which with the addition of abuffer, can drive high current circuits. We have demonstratedthat PWs can last approximately two months, a 4 fold increaseon previous literature. Protoplasmic tubes can be modifiedwith the addition of conductive or magnetic nano-particles toprovide changes in functionality. Conclusions This work has documented novel macro-scaledata transmission through biological material; it has advancedthe field of bio-electronics by providing a cheap and easy togrow conducting bio-material which may be used in futurehybrid electronic technology.
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김규연 ( Marc Miravitlles ),( Pawel Sliwinski ),( Richard Costello ),( Victoria Carter ),( Jessica Tan ),( Therese Laperre ),( Bernardino Alcazar ),( Caroline Gouder ),( Cristina Esquinas ),( Juan Luis G 대한결핵 및 호흡기학회 2017 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.124 No.-
Background/Aim: Chronic obstructive pulmonary disease (COPD) is a heterogeneous condition requiring therapeutic management to be tailored to the clinical characteristics and disease severity of the individual patient. Due to scarcity of studies about racial differences in COPD patients, in this study, we compared clinical characteristics between Asian and other patients of COPD. Method: This was an international, multicenter, prospective study of a cohort of patients with COPD aimed to validate the concept of clinical control in COPD. We compared two subgroups (Asian versus others) by using clinical criteria, questionnaires (COPD Assessment Test -CAT- or Clinical COPD Questionnaire -CCQ-) and recent concept of control. Results: A total of 349 patients were analysed, 110 (32%) patients were Asian and 239 (68%) patients were others. There was a significant difference at sex, smoking status and BMI between Asian and others. Among clinical characteristics, there was a significant difference at median FEV1 (mL), and percentage of patients who have emphysema between two subgroups. Also, number of exacerbation and hospital admission, median CCQ score and recent concept of Impact (Clinical approach by mMRC, rescue medication, time walked/day and sputum color) were the characteristics which show significant disparities between two subgroups. Conclusion: This study showed significant differences in various factors between Asian and other patients of COPD. These results suggest that therapeutic management of COPD should be tailored to the ethnic group of the individual patients
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