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Acute Generalized exanthematous pustulosis Due to oral Use of Blue Dyes
( Osman Sener ),( Osman Kose ),( Ozgur Kartal ),( Mukerrem Safali ) 대한내과학회 2011 The Korean Journal of Internal Medicine Vol.26 No.3
Acute generalized exanthematous pustulosis is a rare severe pustular cutaneous adverse reaction characterized by a rapid clinical course with typical histological findings. It is accompanied by fever and acute eruption of non-follicular pustules overlying erythrodermic skin. The causative agents are most frequently antibacterial drugs. We present a patient with acute generalized exanthematous pustulosis caused by methylene blue and indigotin dyes.
Plasmapheresis in a Patient With "Refractory" Urticarial Vasculitis
Ozgur Kartal,Mustafa Gulec,Zafer Caliskaner,Oral Nevruz,Turker Cetin,Osman Sener 대한천식알레르기학회 2012 Allergy, Asthma & Immunology Research Vol.4 No.4
Immune complexes are found in the circulation of 30%-75% of patients with urticarial vasculitis and much evidence supports the role of these immune complexes in the pathogenesis of urticarial vasculitis. Plasmapheresis is effective for removing these immune complexes; however, there are few reports on the use of plasmapheresis in the treatment of urticarial vasculitis. We describe a case of “refractory” urticarial vasculitis in which the symptoms improved after plasmapheresis treatment. We suggest that plasmapheresis be considered as an option in patients with severe or treatment-resistant urticarial vasculitis.