THE GENERAL ANNUITY CASE OF TIME VALUE OF MONEY: A PEDAGOGICAL APPROACH

Omar M Benkato,Mahmoud M Haddad,Michael N Baur,H Banarjee Rau People&Global Business Association 1996 Global Business and Finance Review Vol.1 No.2

Most finance and related textbooks implicitly assume -in the case of annuity- that the frequency of compounding and the number of payments per year are equal. In this paper; we provide more accurate general equations that permit the equality and the inequality of the number of compounding periods and the number of payments per year. The correct formulation is beneficial to practitioners, regulators and software developers working with annuities because the correct formulas are important in applications related to capital budgeting, pension funds, bond valuation, and bond portfolio immunization.

Identification and differential expression of two dehydrin cDNAs during maturation of Jatropha curcas seeds.

Omar, S A,Elsheery, N I,Kalaji, H M,Ebrahim, M K H,Pietkiewicz, S,Lee, C-H,Allakhverdiev, S I,Xu, Zeng-Fu Consultants Bureau [etc.] 2013 Biochemistry Vol.78 No.5

<P>Plant dehydrin proteins (DHNs) are known to be important for environmental stress tolerance and are involved in various developmental processes. Two full-length cDNAs JcDHN-1 and JcDHN-2 encoding two dehydrins from Jatropha curcas seeds were identified and characterized. JcDHN-1 is 764 bp long and contains an open reading frame of 528 bp. The deduced JcDHN-1 protein has 175 a.a. residues that form a 19.3-kDa polypeptide with a predicted isoelectric point (pI) of 6.41. JcDHN-2 is 855 bp long and contains an open reading frame of 441 bp. The deduced JcDHN-2 protein has 156 a.a. residues that form a 17.1-kDa polypeptide with a predicted pI of 7.09. JcDHN-1 is classified as type Y3SK2 and JcDHN-2 is classified as type Y2SK2 according to the YSK shorthand for structural classification of dehydrins. Homology analysis indicates that both JcDHN-1 and JcDHN-2 share identity with DHNs of other plants. Analysis of the conserved domain revealed that JcDHN-2 has glycoside hydrolase GH20 super-family activity. Quantitative real time PCR analysis for JcDHN-1 and JcDHN-2 expression during seed development showed increasing gene expression of both their transcript levels along with the natural dehydration process during seed development. A sharp increase in JcDHN-2 transcript level occurred in response to water content dropping from 42% in mature seeds to 12% in dry seeds. These results indicate that both JcDHNs have the potential to play a role in cell protection during dehydration occurring naturally during jatropha orthodox seed development.</P>

Apocynin abrogates methotrexate-induced nephrotoxicity: role of TLR4/NF-κB-p65/p38-MAPK, IL-6/STAT-3, PPAR-γ, and SIRT1/FOXO3 signaling pathways

Emad H. M. Hassanein,Ahmed M. Sayed,Omnia A. M. Abd El-Ghafar,Zainab M. M. Omar,Eman K. Rashwan,Zuhair M. Mohammedsaleh,So Young Kyung,Jae Hyeon Park,Hyung Sik Kim,Fares E. M. Ali 대한약학회 2023 Archives of Pharmacal Research Vol.46 No.4

The present study was designed to evaluate the potential renoprotective impacts of apocynin (APC) against nephrotoxicity induced by methotrexate (MTX) administration. To fulfill this aim, rats were allocated into four groups: control; APC (100 mg/kg/day; orally); MTX (20 mg/kg; single intraperitoneal dose at the end of the 5th day of the experiment); and APC +MTX (APC was given orally for 5 days before and 5 days after induction of renal toxicity by MTX). On the 11th day, samples were collected to estimate kidney function biomarkers, oxidative stress, pro-inflammatory cytokines, and other molecular targets. Compared to the MTX control group, treatment with APC significantly decreased urea, creatinine, and KIM-1 levels and improved kidney histological alterations. Furthermore, APC restored oxidant/antioxidant balance, as evidenced by a remarkable alleviation of MDA, GSH, SOD, and MPO levels. Additionally, the iNOS, NO, p-NF-κB-p65, Ace-NF-κB-p65, TLR4, p-p38-MAPK, p-JAK1, and p-STAT-3 expressions were reduced, while the IκBα, PPAR-γ, SIRT1, and FOXO3 expressions were significantly increased. In NRK-52E cells, MTX-induced cytotoxicity was protected by APC in a concentration-dependent manner. In addition, increased expression of p-STAT-3 and p-JAK1/2 levels were reduced in MTX-treated NRK-52E cells by APC. The in vitro experiments revealed that APC-protected MTX-mediated renal tubular epithelial cells were damaged by inhibiting the JAK/STAT3 pathway. Besides, our in vivo and in vitro results were confirmed by predicting computational pharmacology results using molecular docking and network pharmacology analysis. In conclusion, our findings proved that APC could be a good candidate for MTX-induced renal damage due to its strong antioxidative and anti-inflammatory bioactivities.

Optimal WAMS Configuration in Nordic Power System

Mohamed A.M. Hassan,Omar H. Abdalla,Hady H. Fayek,Aisha H.A. Hashim,Siti Fauziah Toha International Journal of Computer ScienceNetwork S 2023 International journal of computer science and netw Vol.23 No.3

The Smart grids are considered as multi-disciplinary power systems where the communication networks are highly employed. This paper presents optimal wide area measurement system (WAMS) configuration in Nordic power system. The transition from SCADA to WAMS becomes now trend in all power systems to ensure higher reliability and data visibility. The optimization applied in this research considered the geographical regions of the Nordic power system. The research considered all the devices of WAMS namely phasor measurement units (PMUs), phasor data concentrators (PDCs) and communication links. The study also presents two scenarios for optimal WAMS namely base case and N-1 contingency as different operating conditions. The result of this research presents technical and financial results for WAMS configuration in a real power system. The optimization results are performed using MATLAB 2017a software application.

Kinetics of Cell Growth and Cyclosporin A Production by Tolypocladium inflatum when Scaling Up from Shake Flask to Bioreactor

( El Enshasy H. ),( Y. Abdel Fattah ),( A. Atta ),( H. Omar ),( S. Abou El Magd ),( R. Abou Zahra ),( M. Anwar ) 한국미생물 · 생명공학회 2008 Journal of microbiology and biotechnology Vol.18 No.1

The kinetics of cell growth and Cyclosporin A (Cyc A) production by Tolypocladium inflatum were studied in shake flasks and bioreactors under controlled and uncontrolled pH conditions. In the case of the shake flask, the production time was extended to 226 h and the maximal antibiotic concentration was 76 mg/l. When scaling up the cultivation process to a bioreactor level, the production time was reduced to only 70 h with a significant increase in both the cell growth and the antibiotic production. The maximal dry cell weights in the case of the controlled pH and uncontrolled pH cultures in the bioreactor were 22.4 g/l and 14.2 g/l, respectively. The corresponding maximal dry cell weight values did not exceed 7.25 g/l with the shake flask cultures. The maximal values for Cyc A production were 144.72 and 131.4 mg/l for the controlled and uncontrolled pH cultures, respectively. It is also worth noting that a significant reduction was observed in both the dry cell mass and the antibiotic concentration after the Cyc A production phase, whereas the highest rate of antibiotic degradation was observed in the stirred tank bioreactor with an uncontrolled pH. Morphological characterization of the micromorphological cell growth (mycelial/pellet forms) was also performed during cultivation in the bioreactor.

Serum Sclerostin Levels in Patients with Human Immunodeficiency Virus Infection and Their Association with Bone Turnover Markers and Bone Mineral Densitometry

Abdulrahman Y. Almansouri,Mohammed E. Abdulfatah,Omar H. Baaqil,Alaa A. Bakheet,Sarah A. Turki,Mamdouh M. Kotb,Alaa Althubaiti,Majed M. Almaghrabi,Abdulrahman M. Althubaiti,Badr M. Madani,Ali S. M. Ja 대한골대사학회 2016 대한골대사학회지 Vol.23 No.1

Background: The aim of the study was to compare serum sclerostin levels in human immunodeficiency virus (HIV)-infected patients and healthy controls, and to evaluate their relationship with bone turnover markers (BTM) and bone mineral density (BMD). Methods: We prospectively studied 33 HIV treatment-naive patients and 63 healthy individuals; match ed for age and sex. Serum sclerostin levels, BTM, BMD were measured. Viral load and cluster of differentiation 4 (CD4) levels were also assessed in HIV-infected patients. Results: The mean±standard deviation (SD) age of sample was 37.6±10.3 years (range, 19 to 59 years). Of the 96 subjects, 58 (60.4%) were male and 38 (39.6%) were female. Infection with HIV is associated with significant reduction in serum sclerostin levels (HIV-infected: 39.4±28.3 vs. non HIV: 76.6±15.7 pmol/L; P<0.001) and a decrease in BMD at femoral neck and lumbar spine compared to healthy controls. Sclerostin however was not correlated with BMD and was not related to age, generally a strong correlation. There were no significant correlations between sclerostin and BTM (P>0.05). Conclusions: These findings suggest that untreated HIV and the resulting immune deficiency and/or systemic inflammation could be an important regulator of serum sclerostin in this population.

Cell Wall Structure of Various Tropical Plant Waste Fibers

H. P. S. Abdul Khalil,M. Siti Alwani,A. K. Mohd Omar 한국목재공학회 2007 목재공학 Vol.35 No.2

Cervical Arthroplasty in the Treatment of Cervical Angina: Case Report and Review of the Literature

Omar M. Al Jammal,Luis Daniel Daz-Aguilar,Shanmukha Srinivas,Jillian Plonsker,Ronald Sahyouni,Martin H. Pham 대한척추신경외과학회 2020 Neurospine Vol.17 No.4

Cervical angina is an often-overlooked etiology of noncardiac chest pain that may mimic true angina pectoris but is due to cervical spine disease. Diagnosis can be difficult, and treatment ranges from conservative therapy to surgical management. However, of patient’s refractory to conservative therapy, approximately ninety percent experience postoperative relief of angina symptoms. Here, we present a case report on cervical angina and performed a systematic review of the literature. A 34-year-old male with prior surgery for thoracic outlet syndrome presented with persistent anterior neck and chest pain as well as posterior left scapular and upper lateral arm pain. The pain was refractory to 12 months of conservative therapy. Cardiac workup was negative and cervical spine imaging revealed a C6–7 herniation with neuroforaminal stenosis. A systematic literature search was conducted in PubMed, Web of Science, and Cochrane databases from database inception to April 2020. Studies reporting cervical level, average symptom duration, location of pain, and postoperative pain improvement were included. The patient's atypical symptoms were completely resolved after C6–7 anterior cervical discectomy and arthroplasty. To our knowledge, this is the first study which reports on the use of arthroplasty in the treatment of cervical angina. The systematic review included 11 articles from 1989–2020 consisting of 1,186 total patients and 109 patients (age range, 36–84 years; 60.7% male) meeting inclusion criteria. Symptom duration range was 2 days to 90 months, with the most common location of pain being localized to the anterior chest wall (66.7% of patients). All patients (100%) had postoperative resolution of their pain symptoms. The most common herniation level was C6–7 (87.3% of patients). We conclude that a broad and multidisciplinary approach is necessary for the diagnosis and management of noncardiac chest pain. When cervical disease is identified as the underlying cause for the angina-like pain, conservative therapy should be sought. Refractory cases should be treated surgically depending on the cervical pathology.

Processing and characterization of nano-magnetic Co0.5Ni0.5Fe2O4 system

N.M. Deraz,Omar H. Abd-Elkader 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.5

Various techniques such as X-ray diffraction (XRD), infrared (IR) spectroscopy, scanning electron micrographs (SEM), energy dispersive X-ray (EDX) and a vibrating sample magnetometer (VSM) were used to investigate the structural, morphological, and magnetic properties of spinel Co0.5Ni0.5Fe2O4 system. XRD and IR analyses enabled us to determine the functional group and structural parameters of Co0.5Ni0.5Fe2O4. EDX measurements showed the concentrations of O, Ni, Fe, and Co species involved in Co0.5Ni0.5Fe2O4 specimen from the uppermost surface to the bulk layers. The magnetization and coercivity of the as synthesized composite were 77 emu/g and 128 Oe, respectively.

Hexon and fiber gene changes in an attenuated fowl adenovirus isolate from Malaysia in embryonated chicken eggs and its infectivity in chickens

Norfitriah M. Sohaimi,Mohd H. Bejo,Abdul R. Omar,Aini Ideris,Nurulfiza M. Isa 대한수의학회 2018 Journal of Veterinary Science Vol.19 No.6

Fowl adenovirus (FAdV) is distributed worldwide and causes economic losses in the poultry industry. The objectives of this study were to determine the hexon and fiber gene changes in an attenuated FAdV isolate from Malaysia in specific pathogen-free chicken embryonated eggs (SPF CEE) and its infectivity in commercial broiler chickens. SPF CEE were inoculated with 0.1 mL FAdV inoculum via the chorioallantoic membrane (CAM) for 20 consecutive passages. The isolate at passage 20 (E20), with a virus titer of 108.7TCID50/mL (TCID50, 50% tissue culture infective dose), was inoculated (0.5 mL) into one-day-old commercial broiler chicks either via oral or intraperitoneal routes. The study demonstrated that 100% embryonic mortality was recorded from E2 to E20 with a delayed pattern at E17 onwards. The lesions were confined to the liver and CAM. Substitutions of amino acids in the L1 loop of hexon at positions 49 and 66, and in the knob of fiber at positions 318 and 322 were recorded in the E20 isolate. The isolate belongs to serotype 8b and is non-pathogenic to broiler chickens, but it is able to induce a FAdV antibody titer. It appears that molecular changes in the L1 loop of hexon and the knob of fiber are markers for FAdV infectivity.