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      • KCI등재

        What Did They Mean by “Calculation Principles”?: Revisiting Argumentative Styles in Late Ming to Mid-Qing Chinese Mathematics

        ( Su Jim-hong ),( Ying Jia-ming ) 한국과학사학회 2016 한국과학사학회지 Vol.38 No.2

        This article discusses the influence that two versions of the Elements had in Ming and Qing China as well as Chinese scholars` efforts to “integrate” (huitong 會通) Western and Chinese mathematics into a unified system in terms of argumentative styles in mathematics. Although much high praise was given to the axiomatic-de-ductive system of Euclid`s Elements, numerical arguments and problem-solving re-main important traits in the works of Chinese scholars. The compilation of the Shuli jingyun 數理精蘊 and the inclusion of another version of the Elements in it again prompted East Asian mathematicians to reflect more upon their methods of argu-mentation, and later scholars began to write texts whose arguments are more abstract than numerical. This paper presents examples taken from the works of several rep-resentative scholars from the late Ming to the mid-Qing periods to argue that their efforts of huitong produced argumentative styles that are a combination of both Chi-nese and Western approaches, and that there was a trend of moving from concrete calculations to general arguments in mathematical texts throughout the course of history. Finally, the authors conclude that what 17<sup>th</sup> and 18<sup>th</sup> century Chinese math-ematicians meant by “calculation principles” (suanli 算理) was never the kind of pure deduction in the Euclidean manner, but a combination of induction and deduc-tion, with the help of intuition, for the purpose of problem-solving.

      • KCI등재

        Silencing of ABCG2 by MicroRNA-3163 Inhibits Multidrug Resistance in Retinoblastoma Cancer Stem Cells

        Ming Jia,Zhenhua Wei,Peng Liu,Xiaoli Zhao 대한의학회 2016 Journal of Korean medical science Vol.31 No.6

        To investigate the function and regulation mechanism of ATP-binding cassette, subfamily G, member 2 (ABCG2) in retinoblastoma cancer stem cells (RCSCs), a long-term culture of RCSCs from WERI-Rb1 cell line was successfully established based on the high expression level of ABCG2 on the surface of RCSCs. To further explore the molecular mechanism of ABCG2 on RCSCs, a microRNA that specifically targets ABCG2 was predicted. Subsequently, miR-3163 was selected and confirmed as the ABCG2-regulating microRNA. Overexpression of miR-3163 led to a significant decrease in ABCG2 expression. Additionally, ABCG2 loss-of-function induced anti-proliferation and apoptosis-promoting functions in RCSCs, and multidrug resistance to cisplatin, carboplatin, vincristine, doxorubicin, and etoposide was greatly improved in these cells. Our data suggest that miR- 3163 has a significant impact on ABCG2 expression and can influence proliferation, apoptosis, and drug resistance in RCSCs. This work may provide new therapeutic targets for retinoblastoma.

      • The study of Harvest System for Organic Perishable Vegetable in Plugs

        ( Jia-ming Yang ),( Xie-zhi Li ),( Kuang-wen Hsieh ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1

        Vegetable is the indispensable food for the daily life of mankind. Due to the demand for increasing the quality of vegetable in Taiwan, the protected culture must be developed for cultivation of vegetable. There are two common approaches of cultivation, including seeding and plug transplant, and both approaches require much labor. By applying the Organic Perishable Vegetable in Plugs planted, the labor problem in the past for plug seeding, sprout cultivation, transplantation and harvesting could be improved. Besides, the yield and quality could be increased. However, the short of labor is still a major problem for harvesting. This study would develop a set of harvesting machinery that is applicable for Organic Perishable Vegetable in Plugs. This could reduce the time and labor for harvesting in fields, and reach the objectives of saving of labor and increasing the productivity.

      • SCIESCOPUSKCI등재

        Multi-layers grid environment modeling for nuclear facilities: A virtual simulation-based exploration of dose assessment and dose optimization

        Jia, Ming,Li, Mengkun,Mao, Ting,Yang, Ming Korean Nuclear Society 2020 Nuclear Engineering and Technology Vol.52 No.5

        Dose optimization for Radioactive Occupational Personal (ROP) is an important subject in nuclear and radiation safety field. The geometric environment of a nuclear facility is complex and the work area is radioactive, so traditional navigation model and radioactive data field cannot form an effective environment model for dose assessment and dose optimization. The environment model directly affects dose assessment and indirectly affects dose optimization, this is an urgent problem needed to be solved. Therefore, this paper focuses on an environment model used for Dose Assessment and Dose Optimization (DA&DO). We designed a multi-layer radiation field coupling modeling method, and then explored the influence of the environment model to DA&DO by virtual simulation. Then, a simulation test is done, the multi-layer radiation field coupling model for nuclear facilities is demonstrated to be effective for dose assessment and dose optimization through the experiments and analysis.

      • KCI등재

        Study of the H2O/Al2O3 Interface and the Acting Mechanism of Water in the Working Electrolyte

        Ming Jia,Qiang Li,Lixiang Li,Liang Cao,Juan Yang,Xiang-Yang Zhou,Liang Ai 대한금속·재료학회 2018 ELECTRONIC MATERIALS LETTERS Vol.14 No.5

        Using a working electrolyte containing mixed solvents of ethylene glycol and N,N-dimethylformamide, this paper presentsa study of the reactions on the H2O/Al2O3 interface with sum frequency vibrational spectroscopy and the effects of differentwater content on the performance of the working electrolyte and an aluminum electrolytic capacitor and summarizes the rulesof the variations in the performance parameters of the working electrolyte and aluminum electrolytic capacitor with respect tothe water content. The results demonstrate that, when the water content is increased from 2.5 to 15%, the conductivity of theworking electrolyte increased by 930 μS/cm, and the sparking voltage decreased by 27 V. Also, the increased water contentcauses lower oxidation efficiency and lower thermal stability. The leakage current of the aluminum electrolytic capacitorafter high-temperature storage increases with an increase in the water content, and the attenuation rate of capacitor’s thelow-temperature capacitance decreases with an increase in the water content.

      • KCI등재

        Construction of a 2D Co(II) Coordination Polymer with (4,4)-Connected Topology: Synthesis, Crystal Structure, and Surface Photo-electric Property

        Jia-Ming Li 대한화학회 2014 Bulletin of the Korean Chemical Society Vol.35 No.4

        A 2D grid-like (4, 4)-connected topology coordination polymer, [Co(BTA)2(H2O)2]n (1), where HBTA = 2- (1H-benzotriazol-1-yl)acetic acid, has been synthesized by hydrothermal method and characterized by single crystal X-ray diffraction, IR spectroscopy, elemental analysis and surface photovoltage spectroscopy (SPS). X-ray diffraction analyses indicated that 1 displays octahedral metal centers with secondary building units (SBUs) [Co(BTA)2(H2O)2] bridged by the BTA− ligands. In the crystal, the 2D supramolecular architecture is further supported by O–H···O, O–H···N, C–H···O hydrogen bonds and π···π stacking interactions. The SPS of polymer 1 indicates that there are positive response bands in the range of 300–600 nm showing photo-electric conversion properties. There are good relationships between SPS and UV–Vis spectra.

      • KCI등재

        Acupuncture for ventilator-dependent patients at a hospital-based respiratory care center: A randomized controlled trial

        Jia-Ming Chen,Wan-Li Chiang,Bin-Chuan Ji,Ruei-Jhe Jhang,Pei-Hsin Chen,Ya-Lun Li,Che-Ju Chang,Sung-Yen Huang,Tsung-Chieh Lee,Chia-Yun Chen,Ching-Hsiung Lin,Sheng-Hao Lin 한국한의학연구원 2023 Integrative Medicine Research Vol.12 No.4

        Background: In intensive care units, mechanical ventilation is an important therapy to help patients with dysp- nea. However, long-term ventilator dependence would consume huge medical resources and increase the risk of morbidity and mortality. The aim of the study was to examine the efficacy of the acupuncture combined with western medical care on ventilator parameters in ventilator-dependent patients. Methods: In this clinical trial, 80 ventilator-dependent patients aged 20 to 80 years old were randomly assigned to acupuncture group and control group in the respiratory care center (RCC) of Changhua Christian Hospital. Besides regular medical care and therapy, participants in the acupuncture group received acupuncture therapy at the same 17 acu-points for 20 minutes once a day, a total of 12 sessions. The ventilator parameters were recorded to evaluate the respiratory efficiency for all participants. The primary outcome was rapid shallow breathing index (RSBI), and secondary outcomes were respiratory rate (RR), tidal volume (TV) and ventilation per minute (MV). Results: Though there was no significant difference in the parameter between the acupuncture group and the control group, we found the trend of decreasing RSBI in the acupuncture group. In subgroup analyses, the mean of RSBI significantly decreased 16.02 (with the SD in 60.84) in acupuncture group, while it increased 17.84 (with the SD in 39.38) in control group (p = 0.036) after 12 sessions. Conclusion: Acupuncture treatment can improve breathing ability of patients with respirator dependence in respiratory care center.

      • KCI등재

        BRCA1 Reversion Mutation Confers Resistance to Olaparib and Camrelizumab in a Patient with Breast Cancer Liver Metastasis

        Jia-Ni Pan,Lei Lei,Wei-Wu Ye,Xiao-Jia Wang,Wen-Ming Cao 한국유방암학회 2021 Journal of breast cancer Vol.24 No.5

        Reversion mutations are associated with clinical resistance to poly(ADP-ribose) polymerase inhibitors (PARPi). Here, we describe the detection of a BRCA1 reversion mutation in a 39-year-old woman with metastatic breast cancer harboring a heterozygous germline BRCA1 exons 7–8 deletion who received PARPi olaparib combined with immune checkpoint inhibitor camrelizumab as third-line therapy. During progression from the olaparib and camrelizumab combination therapy, we identified via genomic sequencing a novel 7-base pair somatic deletion in BRCA1 (c.617_623delACAAATC). Sequence analyses indicated that this mutation realigned the reading frame of BRCA1, which potentially led to the reversal of its normal function and conferred resistance to PARPi.

      • KCI등재후보

        Characterization of Ecdysteroid UDP-Glucosyltransferase Gene Promoter from Bombyx mori Nucleopolyhedrovirus

        Xing-Jia Shen,Yong-Zhu Yi,Shun-Ming Tang,Zhi-Fang Zhang,Yi-Ren Li,Jia-Lu He,Xiang-Fu Wu 한국잠사학회 2004 International Journal of Industrial Entomology Vol.8 No.2

        Bombyx mori nucleopolyhedrovirus (BmNPV) ecdysteroid UDP-glucosyltransferase gene (egt) promoter fragments of different lengths were amplified from BmNPV ZJ-8 genomic DNA by PCR. Reporter plasmids pBmegt542-luc, pBmegt309-luc and pBmegt159- luc with luciferase (luc) driven by egt promoters were constructed. Both in vitro and in vivo expressions showed that BmNPV egt promoter activity requires the transactivation of viral factor(s), and expression of luc was detected earliest at 24 hrs post infection (pi). BmNPV ZJ-8 homologous region 3 (hr3) increased the expression of luc by over 1,600-fold. Molting hormone of 1.0 ~ 2.0 mg/ml can dramatically down regulate expression of luc. Juvenile hormone analogue of 0.5 ~ 2.0 mg/ml increased expression of luc by 145.8% to 75.7%. Deletion assay revealed that the promoter fragment of 159 bp contains the basal promoter structure; Promoter fragments of 309 bp and 542 bp showed similar but much higher transcriptional activities than that of 159 bp, suggesting that nucleotide from -159 to -309 nt upstream the translation initiation site harbors the main cis-acting elements.

      • KCI등재

        소셜네트워킹 사이트의 e-고객충성도에 관한 실증연구

        가명호 ( Ming Hao Jia ),정대율 ( Dae Yul Jeong ) 한국정보시스템학회 2010 情報시스템硏究 Vol.19 No.2

        웹 2.0 기술의 급속한 발전은 인터넷을 통한 커뮤니티 형성을 효과적으로 가능하게 함으로서 소셜네트워킹 사이트(SNS)의 급속한 성장을 가져왔다. 본 연구는 소셜네트워킹 사이트의 고객충성도를 높이는 요인이 무엇인가를 실증적으로 밝히는데 있다. 연구모형은 세 개의 독립요인(시스템 능력, 정보 적절성, 콘텐츠 가치)과 두 개의 매개요인(사이트 매력도, e-고객만족)으로 구성되어 있다. 중국인들을 대상으로 한 실증연구 결과 정보 적절성과 콘텐츠 가치가 사이트 매력도에 직접 영향을 미치며, 이는 다시 고객만족을 통하여 고객의 충성도에 간접적으로 영향을 미치는 것으로 나타났다. 또한 사이트 매력도는 고객만족과 고객충성도에 강력한 영향을 미치는 것으로 나타났다. 구조모형에 대한 경로분석결과 사이트 매력도는 고객만족도를 높이는 중요한 매개변수임을 밝히고 있다. 본 연구에서는 소셜네트워크 사이트에서 이 매개변수들을 어떻게 하면 효과적으로 높일 것인가에 대한 다양한 시사점들을 제시하고 있다.

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