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      • Seroprevalence and Risk Perception of TransfusionTransmissible Hepatitis among Voluntary Blood Donors in Western Nepal

        ( Bimala Sharma ),( Bishnu Raj Tiwari ),( Gyanendra Bikram Shah ),( Krishna Gurung ),( Mamita Khaling Rai ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

        Aims: The study aimed to assess the seroprevalence and risk perception of hepatitis B virus (HBV) and hepatitis C virus (HCV) among voluntary blood donors in the Western Region of Nepal. Methods: A total of 13,079 voluntary blood donors aged 18- 60 years attending from July, 2016 to June, 2017 were enrolled in the study. Perceived risk of HBV and HCV was measured by Likert-type scale: ‘no risk’, ‘little’, ‘moderate’, ‘high’ and ‘very high’ risk, ranging from 1 to 5. Blood samples were analyzed for the presence of HBsAg and HCV antibodies by ELISA at Western Regional Blood Transfusion Service Center. Proportion, mean, chi-square test and independent samples t-test were applied for statistical analysis. Results: Of the total, 83.8% participants were males; 88.2% were married; and mean age of the participants was 30.0 years. Seroprevalece of HBV was 0.3% in the total samples; 0.3% among males and 0.2% among females; and 0.5% among unmarried donors. Seroprevalece of HCV was 0.1% in the total; 0.1% among males and one case among females; 0.2% among unmarried; and 0.2% among those who ever pierced tattoo. No significant difference was observed in the seroprevalence of HBV and HCV among those who reported having multiple sexual partners and single sexual partner; and among Tattoo piercing and non-piercing respondents (P>0.05). Mean risk perception of HBV was slightly greater (x¯, 2.75; SD, ±1.24) than that of HCV (x¯, 2.68; SD, ±1.22). The mean risk perception of both types did not differ significantly across gender, age, marital status; and having multiple sexual partners and tattoo piercing practices (P>0.05). Conclusions: The study revealed low seroprevalence and low risk perception of HBV and HCV among voluntary blood donors in Western Nepal. Although the seroprevalence is low among voluntary blood donors, there might be higher prevalence of HBV and HCV in the community.

      • Seroprevalence and Risk Perception of Hepatitis B and Hepatitis C among Healthy-Looking Adults in Nepal

        ( Bishnu Raj Tiwari ),( Gyanendra Bikram Shah ),( Krishna Gurung ),( Mamita Khaling Rai ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

        Aims: Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are rapidly spreading in the developing countries. The study assessed seroprevalence and risk perception of HBV and HCV among healthylooking adults in Western Region, Nepal Methods: A cross-sectional study was conducted among voluntary blood donors in collaboration with Regional Blood Transfusion Service, Kaski. A total of 1878 adults (18-58 years) attending for voluntary blood donation from November, 2016 to February, 2017 at Pokhara valley was enrolled in the study. Background characteristics and risk perception was assessed by interview. Risk perception was measured by Likert-type scale: ‘no risk’, ‘little’, moderate, high and very high risk, ranging from 1 to 5. Blood samples were analyzed for the presence of HCV antibodies and HBsAg by ELISA. Proportion of seropositive status was computed, and t-test was applied to find out the mean difference. Results: Of total, 86.9% were male, 62.7% were 20-34 years old, 62.6% married, 5% had multiple sex partners, and 9.2% made tattoo piercing. Seroprevalence of HBsAg and anti-HCV antibodies was 0.7% and 0.4%, respectively. Seroprevalence of HBsAg was 0.7% in male and 0.8% in female; 0.9% in married; 1.1% in subjects with multiple sex partners; and 0.9% in ≥35 years old. Seroprevalence of anti-HCV antibodies was 0.5% in male and 0.0% in female, 0.6% in married, 0.9% in ≥ 35 years old, and 1.2% in tattoo piercing group. Mean risk perception of HBVand HCV was 2.73 and 2.67 in total (P<0.05); 2.69 and 2.64 in male, and 2.93 and 2.84 in female, respectively, both were significantly higher in female (p<0.05). Conclusions: This indicates intermediate level of endemicity of HBV and lower seroprevalnce of HCV infection in Nepal. Higher seroprevalence of HBsAg was found among married, having multiple sex partners and older; and of anti-HCV antibodies among male, married, older and tattoo piercing individuals. However, risk perception of both HBV and HCV was higher among females.

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