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        Topical Anti-Inflammatory Activity of a Monofloral Honey of Mimosa scabrella Provided by Melipona marginata During Winter in Southern Brazil

        Débora M.Borsato,Arthur S. Prudente,Patrícia M. Döll-Boscardin,Aurélio V. Borsato,Cynthia F.P. Luz,Beatriz H.L.N.S. Maia,Daniela A. Cabrini,Michel F. Otuki,Marilis D. Miguel,Paulo V. Farago,Obdulio G. 한국식품영양과학회 2014 Journal of medicinal food Vol.17 No.7

        Melipona marginata is an endangered species of stingless bee from Brazil that produces honey with particular physicochemical features and a remarkable exotic flavor. To the best of our knowledge, this is the first report devoted to exploring the medicinal potential of this honey. Thus, the aim of this paper was to investigate the potential anti-inflammatory activity of honey extract from M. marginata on skin inflammation. The honey sample was classified as a monofloral honey of Mimosa scabrella. The presence of 11 phenolic compounds as kaempferol and caffeic acid was detected using the highperformance liquid chromatography-electrospray ionization-tandem mass spectrometry (HPLC-UV-ESI-MS) method. The anti-inflammatory activity was measured using a 12-O-tetradecanoylphorbol-13-acetate-induced ear edema model of inflammation in mice. The topical application of the M. marginata honey extract (1.0 mg/ear) was able to reduce ear edema with an inhibitory effect of 54 – 5%. This extract decreased the myeloperoxidase activity in 75 – 3%, which suggests a lower leucocyte infiltration that was confirmed by histological analysis. This extract also provided a reduction of 55 – 14% in the production of reactive oxygen species. This anti-inflammatory activity could be due to a synergic effect of the phenolic compounds identified in the honey sample. Taken together, these results open up new possibilities for the use of M. marginata honey extract in skin disorders.

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        Study of Chloride Corrosion Organic Inhibitors in Alkaline Pore Solution

        ( M. Cabrini ),( S. Lorenzi ),( T. Pastore ),( S. Pellegrini ) 한국부식방식학회(구 한국부식학회) 2018 Corrosion Science and Technology Vol.17 No.5

        This paper compares the inhibition properties of aspartic and lactic acid salts with nitrite ions and their effect on critical chloride concentration. The tests were carried employing carbon steel specimens in saturated lime solution with varying pH in the range between13 to 13.6. The critical chloride concentration was estimated through multiple specimen potentiostatic tests at potentials in the usual range for passive rebar in the alkaline concrete of atmospheric structures. During tests, chloride salt was added every 48 h until all the specimens showed localized attacks. The cumulative distribution curves, i.e. the number of corroded specimens as a function of the chlorides concentration was obtained. Furthermore, IR spectra were recorded for the evaluation of the presence of the organic inhibitors on the passivity film. The results confirmed the inhibitory effect of 0.1M aspartate comparable with nitrite ions, at a similar concentration. Addition of calcium lactate did not result in an increase in the critical chloride concentration. However, the formation of a massive scale containing the substance that could reduce the corrosion propagation was observed.

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