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- 저자 : ( Lixia Lin ) (검색결과 4 건)
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Qian Lin,Jianyong Feng,Lixia Zhao 한국섬유공학회 2023 Fibers and polymers Vol.24 No.10
Due to the low melt index of polylactic acid (PLA) polymer, it is difficult to melt-blown processing. Here, a new modified method to obtain a high melt index of PLA polymer and melt-blown nonwoven cloth was studied. PLA polymers are modified by the thermally degraded method of stannous octoate (Sn(Oct)2) and polyethylene glycol (PEG) to obtain a high melt index (1054 g/10 min) in comparison with a low melt index (23 g/10 min) of original unmodified PLA polymer. The fiber of modified PLA polymer melt-blown cloth is obviously thinner, having sub-micron fibers, the smallest fiber is about 200 nm. From our test, modified PLA polymer melt-blown cloth has good oil absorption, oil–water separation, and potential air filtration property. In terms of degradation, the modified PLA polymer melt-blown cloth showed excellent degradation performance in basic aqueous solutions at 55 °C at pH 12, reaching a degradation rate of around 95% at 60 h.
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Role of IFNLR1 gene in PRRSV infection of PAM cells
Ming Qin,Wei Chen,Zhixin Lin,Lixue Wang,Lixia Ma,Jinhong Geng,Yu Zhang,Jing Zhao,Yong-Qing Zeng 대한수의학회 2021 Journal of Veterinary Science Vol.22 No.3
Background: Interferon lambda receptor 1 (IFNLR1) is a type II cytokine receptor that clings to interleukins IL-28A, IL29B, and IL-29 referred to as type III IFNs (IFN-λs). IFN-λs act through the JAK-STAT signaling pathway to exert antiviral effects related to preventing and curing an infection. Although the immune function of IFN-λs in virus invasion has been described, the molecular mechanism of IFNLR1 in that process is unclear. Objectives: The purpose of this study was to elucidate the role of IFNLR1 in the pathogenesis and treatment of porcine reproductive and respiratory syndrome virus (PRRSV). Methods: The effects of IFNLR1 on the proliferation of porcine alveolar macrophages (PAMs) during PRRSV infection were investigated using interference and overexpression methods. Results: In this study, the expressions of the IFNLR1 gene in the liver, large intestine, small intestine, kidney, and lung tissues of Dapulian pigs were significantly higher than those in Landrace pigs. It was determined that porcine IFNLR1 overexpression suppresses PRRSV replication. The qRT-PCR results revealed that overexpression of IFNLR1 upregulated antiviral and IFN-stimulated genes. IFNLR1 overexpression inhibits the proliferation of PAMs and upregulation of p-STAT1. By contrast, knockdown of IFNLR1 expression promotes PAMs proliferation. The G0/G1 phase proportion in IFNLR1-overexpressing cells increased, and the opposite change was observed in IFNLR1-underexpressing cells. After inhibition of the JAK/STAT signaling pathway, the G2/M phase proportion in the IFNLR1-overexpressing cells showed a significant increasing trend. In conclusion, overexpression of IFNLR1 induces activation of the JAK/STAT pathway, thereby inhibiting the proliferation of PAMs infected with PRRSV. Conclusion: Expression of the IFNLR1 gene has an important regulatory role in PRRSV-infected PAMs, indicating it has potential as a molecular target in developing a new strategy for the treatment of PRRSV.
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Socially Aware Device-to-multi-device User Grouping for Popular Content Distribution
( Jianlong Liu ),( Wen’an Zhou ),( Lixia Lin ) 한국인터넷정보학회 2020 KSII Transactions on Internet and Information Syst Vol.14 No.11
The distribution of popular videos incurs a large amount of traffic at the base stations (BS) of networks. Device-to-multi-device (D2MD) communication has emerged an efficient radio access technology for offloading BS traffic in recent years. However, traditional studies have focused on synchronous user requests whereas asynchronous user requests are more common. Hence, offloading BS traffic in case of asynchronous user requests while considering their time-varying characteristics and the quality of experience (QoE) of video request users (VRUs) is a pressing problem. This paper uses social stability (SS) and video loading duration (VLD)-tolerant property to group VRUs and seed users (SUs) to offload BS traffic. We define the average amount of data transmission (AADT) to measure the network’s capacity for offloading BS traffic. Based on this, we formulate a time-varying bipartite graph matching optimization problem. We decouple the problem into two subproblems which can be solved separately in terms of time and space. Then, we propose the socially aware D2MD user selection (SA-D2MD-S) algorithm based on finite horizon optimal stopping theory, and propose the SA-D2MD user matching (SA-D2MD-M) algorithm to solve the two subproblems. The results of simulations show that our algorithms outperform prevalent algorithms.
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