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Invited Review : Clinical and Basic Studies of Muscle Strain Injury
( Koichi Nakazato ),( Kih Yok Lee ),( Karina Kouzaki ),( Kenji Hiranuma ),( Seok Ki Min ),( Eisuke Ochi ),( Hong Sun Song ) 한국스포츠정책과학원(구 한국스포츠개발원) 2013 International Journal of Applied Sports Sciences Vol.25 No.1
In this review, we gleaned clinical and basic studies of muscle strain injury. In clinical situation, thigh muscles, especially hamstrings, are frequently suffered. Sudden eccentric contraction (EC), imbalance of muscle strength, preexisting strain injuries are significant risk factors. Magnetic resonance and ultrasonography imaging provides useful information for diagnosis and care. Atrophy and scar formation can be raised as characteristics in chronic change. Despite of these information, definition and classification for strain injury is still under development. In basic aspect, EC-induced muscle damage is frequently used as a muscle strain injury model. With in vivo EC model, we showed that (1) cellular myogenic events are associated with torque recovery after EC-induced muscle injury, (2) muscle protein degradation is induced by severe ECs. To reproduce unique events in muscle strain injury, such as muscle atrophy, fibrosis and recurrence, is a key to simulate muscle strain injury in animal and human models.