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RISS 인기검색어
- 검색키워드
- 저자 : ( Kae Yol Lee ) (검색결과 12 건)
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이계열,유병권,박광석,홍승길 中央醫學社 1973 中央醫學 Vol.24 No.5
This experiment was conducted in order to find out the hernatologic responses to hyperbaric pressure in rabbits. Twenty-nine male rabbits weighing about 2 kg were used. Blood samples were collected through the ear vein of rabbit with heparinized syringe before and after exposure to 5 atmospheric air pressure absolute (5 ATA) in overcompression chamber. The analyzed items were blood pictures; RBC, WBC, hemoglobin, hematocrit, chemical compositions; glucose, cholesterol, specific gravity, pH, and plasma electrolytes; Na, K, Cl. The results obtained were as follows: 1. Hyperbaric pressure did not influence on the numbers of RBC and WBC. 2. Hemoglobin and hematocrit levels were decreased significantly by hyperbaric pressure. 3. Blood cholesterol level did not change, while the glucose level, specific gravity and pH changed significantly. 4. Plasma electrolytes were increased in K, not in Na and Cl.
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GABA가 만성저산소 환경에 폭로한 토끼의 장관운동에 미치는 영향
이계열,김원석,이근묵,강석원,김병권,박용덕 최신의학사 1971 最新醫學 Vol.14 No.1
It has long been recognized that GABA have an initial inhibitory effect on the heart and intestine of Crustacea and Mammalia. But the effect -of GABA on the hypoxic -intestine is not known. In order 'to find ,lout -the effect of GABA on the intestinal motility of rabbits exposed to chronic hypoxia,' the present experiments were performed on albino rabbits of both sexes, weighing approximately 2 kg using Magnus method and the animals divided into three groups, the control, chronic hypoxia and recovery group. Control group was normal, a group of chronic hypoxia rabbit was exposed 8 hours a day to simulated altitude of 18000 feet-25000 feet for a period of 10 weeks, and recovery group was past 10 days after 10 weeks exposure to the chronic hypoxia. The results were summarized as follows: 1. The RBC count and hemoglobin concentration increased due to the exposure to chronic hypoxia. These changes returned to normal progressively after withdrawal of exposure to hypoxia. 2. GABA inhibited the intestinal movement of normal rabbit. 3. GABA had no effect or rather increased the contractility of intestinal movement of rabbit exposed to chronic hypoxia. 4. The initial inhibitory action of GABA on intestinal motility was weakened in the rabbit of recovery group compared to control group. 5. Above results suggest that the period of 10 days was not sufficient to recover from chronic hypoxia.
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이계열,차영선 우석대학교 의과대학 1971 우석의대잡지 Vol.8 No.1
To investigate the changes of gastric motility and tonus as the anus or rectum is distended, this study was planned in unanesthetized 46 dogs and conscious 6 human subjects. In dog, the effects of anus or rectum distension on gastric and respiratory movements were recorded on kymograph smoked drum using balloon method and recorded ECG. In man, the effects of anus or rectum distension on gastric movements were traced on polygraph paper using balloon method with respiration, blood pressure and ECG. The results obtained were as follows: 1. In dogs, distension of anus with centrifuge tube(2㎝ in diameter), of rectum with pressure(average 50㎜Hg) induced initial inhibition of the gastric motility or tonus suggesting ano-gastric, recto-gastric inhibitory reflexes. 2. In dogs, deep inspiratory movements and decreased heart rates were observed during distension. 3. α-Adrenergic blocking with drugs of ergotamine tartrate, phenoxybenzamine hydrochloride, β-adrenergic blocking with propranolol hydrochloride and both receptors blocking did not influence the ano-gastric and recto-gastric inhibitory reflexes in dogs. 4.. Atropinization blocked this reflexes partially, but vagotomy blocked completely. Above results suggest that the gastric inhibitory reflexes induced by distension of anus or rectum must be vagal origin transmitted not only acetycholine but the other chemical substances. 5. In man, distension of anus or rectum could not induce the gastric inhibitory reflex. 6. In one case of human subjects, distension of anus and rectum induced bradycardia with blood pressure fall suggesting increased vagal tone.
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이계열,홍승길,신영철,유총근,성양호 최신의학사 1972 最新醫學 Vol.15 No.9
To investigate the effects of hypoxic and hyperoxic conditions on the erythrocyte, erythropoietin activity and heart metabolism, this experiment was performed to the animals of 24 rabbits and about 300 mice. Hypoxic condition was induced by flowing the gas mixtures which contain 8% oxygen and 92% nitrogen into a closed hyperbaric chamber, and hyperoxic condition by flowing the gas mixture containing 40% oxygen and 60% nitrogen for 5 hours per day during the period of 15 days respectively. The flow rates of each gas mixtures were corrected by analyzing the oxygen content of outlet gases with micro-Scholander apparatus. Blood samples were obtained from the ear vein with heparinized syringes at the end of one-week and two-week exposure for the detemination of RBC, hemoglobin, hematocrit and RBC fragility and also arterial blood serum was collected and stored in freezer for the measurement of erythropoietin activity. This serum was injected subcutaneously to the plethoric mice and determined 59Fe incorporation rate. Oxygen consumption and lactic acid level of left ventricle excised from the heart of sacrificed rabbit were determined. The results obtained were as follows: 1. The increase of RBC count was more prominent in hypoxic group than in hyperoxic group. 2. Hemoglobin and hematocrit were increased significantly in hypoxic group and decreased in hyper Toxic group. 3. MCV, MCHC and MCH were increased in hypoxic group and decreased in hyperoxic group representing macrocytic shift in hypoxia and microcytic shift in hyperoxia. 4. Erythrocyte fragility was decreased in hypoxic group and increased in hyperoxic group. 5. Erythropoietin activity was increased in hypoxic group significantly, and decreased in hyperoxic group. 6. Oxygen consumption arid lactic acid level were elevated in hypoxia and depressed in hyperoxic group.
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이계열,지선호,홍승길,성양호,Lee, Kae-Yol,Chee, Sun-Ho,Hong, Seung-Kil,Sung, Yang-Ho 대한생리학회 1972 대한생리학회지 Vol.6 No.2
Contrary to most of European and American investigators failed to find out the seasonal variations of basal metabolic rate in man, Japanese and Korean investigators reported the increase in winter, decrease in summer season. But the causes of variation were not found clearly. To find out whether metabolic acclimatization to climate could be arise or not in human being, the basal metabolic rate was determined monthly for a period of one year in Airmen volunteers who live in Seoul, with 9 l Collins spirometer. The results obtained were as follows: 1. The average ambient temperature was lowest in February $(-5.88^{\circ}C)$ and highest in July $(27.34^{\circ}C)$. 2. Basal metabolic rate was lowest in June and highest in December showing seasonal variations. Interestingly, the increase of basal metabolic rate followed after the drop of ambient temperature below $0^{\circ}C$ (December) and the decrease followed after the elevation of ambient temperature from optimum to hot (June) or cold to warm (March). 3, Mean skinfold thickness increased in spring, decreased in winter. 4. These findings indicate that the basal metabolic rate of Korean reveals the seasonal variation affected by ambient temperature highly.
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홍승길,이계열,박용덕 최신의학사 1972 最新醫學 Vol.15 No.9
To investigate the effects of hypothalamic lesion on the erythropoietic function and the regulation of body temperature, bilateral preoptic regions of rabbit hypothalamus were destroyed electrolytically. The reticulocytes count, hematocrit and rectal temperature were evaluated to these lesioned animals and exposed to 8% oxygen environment for erythopoietic response to hypoxia. The results obtained were as follows: 1. The reticulocytes and hematocrit values were decreased in the lesioned animals of preoptic region of hypothalamus. 2. Destruction of preoptic region of hypothalamus leads to decrease of rectal temperature. 3. There were no changes of erythropoietic responses to hypoxia in the preoptic lesioned ainmals. 4. Destruction of preoptic region of hypothalamus can not inhibit the erythropoietic response to hypoxia. It was suggested that the regulating center for erythropoiesis and body temperature did not exist in a local point but in scattered area of hypothalamus.
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