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      • The practical difficulties and path optimization of primary school to promote emergency education in china

        JI dong-yan,WU xiao-tao 위기관리 이론과 실천 2016 위기관리 이론과 실천 학술대회 Vol.2016 No.08

        Proceed with work of emergency education in elementary school is the basis of enhancing the level of emergency management. Through the analysis and summary of related concepts to emergency education, the paper defined the concept of emergency education, With the basics of which to look deeply into the current situation and difficulties of the primary school to push emergency education in our country from the aspect of the government, society and schools. Then, the paper put forward the path optimization of the primary school to push emergency education from the aspect of perfecting laws and regulations, facilitating social participation, standardizing the education content, and making evaluation mechanism.

      • Serum Carbohydrate Antigen 19-9 as an Indicator of Liver Metastasis in Colorectal Carcinoma Cases

        Dong, Hang,Tang, Jie,Li, Long-Hao,Ge, Jun,Chen, Xin,Ding, Jing,Men, Hai-Tao,Luo, Wu-Xia,Du, Yang,Li, Cong,Zhao, Feng,Chen, Ye,Cheng, Ke,Liu, Ji-Yan Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2

        Purpose: The liver is the organ to which colorectal carcinomas (CRCs) most commonly metastasize, and surgical resection has been established as the most effective and potentially curative treatment for CRC with liver metastasis (LM). Therefore, surveillance of LM is vital for improvement of prognosis of CRC patients. In this study, we aimed to explore the potential value of carbohydrate antigen 19-9 (CA 19-9), carcinoembryonic antigen (CEA), and marker enzymes in indicating LM with CRC. Methods: Three groups of eligible patients with metastatic cancers were retrospectively included: CRC patients with LM (CRC-LM) or without LM (CRC-NLM), and non-CRC patients with LM (NCRC-LM). All metastatic lesions were identified by CT or MRI. Data on characteristics of the patients, the primary site, the locations of metastasis, CA 19-9, CEA, and biochemical parameters were collected for analysis. Results: A total of 493 patients were retrospectively included. More alcohol consumption was found in CRC-LM than CRC-NLM. Some biochemical enzymes were found to be significantly higher in groups with LM than without (CRC-LM or NCRC-LM v.s CRC-NLM). Both CEA and CA 19-9 were much higher in CRC-LM than CRC-NLM or NCRC-LM. For CRC patients, CA 19-9, ${\gamma}$-glutamyl transpeptidase, CEA and alcohol consumption were identified as independent factors associated with LM. Conclusion: Our analysis suggested the CA 19-9 might be a potential valuable indicator for LM of CRC in the clinic.

      • 생육시기에 따른 품종별 양마 잎의 항산화 활성과 플라보노이드 함량의 변화

        Ji Min Son,Cheng Wu Jin,Si Yong Kang,Dong Ha Cho 한국약용작물학회 2016 한국약용작물학술대회 발표집 Vol.2016 No.10

        Background : This study analyzes changes in DPPH radical scavenging activity, total polyphenol contents, and total flavonoid contents of six different kinds of Kenaf (Hibiscus cannabinus L.) leaves which are identified as herbaceous plants, and are living in the subtropics. The data of changes in polyphenol, flavonoid contents and DPPH radical scavenging activities were analyzed, based on two different lengths of growth period.. Methods and Results : The six different kinds of cultivars ; Jangdae in Korea, and El-1, R, G-1, Ef-1, Ef-2 in the State of Israel were collected on the 43th and 62nd day from when they have planted. The collected cultivars were dried at 70℃, and 80% of methanol concentration was applied to each ground specimen. Extraction was made by immersion and filtering process at room temperature. Samples were classified into two groups, one for cultivars that were collected on the 43th day, and the other for the collection of the 62nd day. We measured the rate of DPPH radical scavenging activity, total polyphenol contents, and total flavonoid contents for every Samples. For the group of the 43th day collection, Jangdae showed the highest rate of radical scavenging activity as well as the highest polyphenol contents, and El-1had the highest flavonoid contents. For the group ofthe 62nd day collection, R demonstrated not only the highest contents of polyphenol and flavonoid, but alsothe highest rate of antioxidant activity. When we compared each cultivar from another regardless its date of collection, R resulted biggest increase in all of functional components. Conclusion : Based on the test results, useful components and antioxidant activity of kenaf leaves increase in proportion to longer growing period. Particularly, the study indicates that R can be utilized as a cosmetic ingredient crop, as the rate of increase in polyphenol and flavonoid contents were highest among the six cultivars.

      • SCOPUSKCI등재

        Failure patterns of cervical lymph nodes in metastases of unknown origin according to target volume

        Dong-Yun Kim,Dae Seog Heo,Bhumsuk Keam,Chan Young Ock,Soon Hyun Ahn,Ji-hoon Kim,Kyeong Cheon Jung,Jin Ho Kim,Hong-Gyun Wu 대한방사선종양학회 2020 Radiation Oncology Journal Vol.38 No.1

        Purpose: This study was aim to evaluate the patterns of failure according to radiotherapy (RT) target volume for cervical lymph nodes in metastases of unknown primary origin in head and neck region (HNMUO). Materials and Methods: Sixty-two patients with HNMUO between 1998 and 2016 were retrospectively reviewed. We analyzed the clinical outcomes and primary site failure depending on the radiation target volume. The target volume was classified according to whether the potential head and neck mucosal sites were included and whether the neck node was treated involved side only or bilaterally. Results: Potential mucosal site RT (mucosal RT) was done to 23 patients and 39 patients did not receive mucosal RT. Mucosal RT showed no significant effect on overall survival (OS) and locoregional recurrence (LRR). The location of primary site failure encountered during follow-up period was found to be unpredictable and 75% of patients with recurrence received successful salvage therapies. No significant differences in OS and LRR were found between patients treated to unilateral (n = 35) and bilateral neck irradiation (n = 21). Treatment of both necks resulted in significantly higher mucositis. Conclusions: We found no advantages in OS and LRR of patients with HNMUO when mucosal sites and bilateral neck node were included in the radiation target volume.

      • Lack of Association of the MDR1 C3435T Polymorphism with Susceptibility to Gastric Cancer and Peptic Ulcer: a Systemic Review and Meta-analysis

        Wu, Dan-Dan,Zhang, Ji-Xiang,Li, Jiao,Dong, Wei-Guo Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.7

        Background: The multidrug resistance 1 gene (MDR1) C3435T polymorphism has been demonstrated to influence the P-glycoprotein (P-gp) activity level which is related to inflammation and carcinogenesis. This meta-analysis was performed to estimate the association between the MDR1 C3435T polymorphism and the risk of gastric cancer (GC) and peptic ulcer (PU). Materials and Methods: A literature search was conducted with PubMed, Embase and the Cochrane library up to November 2013. Odds ratios (ORs) with 95% confidence intervals (CIs) were used to assess the strength of association. Data were analyzed using Review Manager (Version 5.2), and Stata package (version 12.0) for estimation of publication bias. Results: Six case-control studies were included, of which five were for GC and two for PU. Overall, no evidence was found for any association between the MDR1 C3435T polymorphism and the susceptibility to GC and PU. In the stratified analysis by H. pylori infection status, stage and histology classification of GC, and PU type, there was still no significant association between them. Conclusions: This meta-analysis suggested that the MDR1 C3435T polymorphism is not associated with susceptibility to GC and PU. Large and well-designed studies are warranted to validate our findings.

      • The practical difficulties and path optimization of primary school to promote emergency education in china

        JI dong yan,WU xiao tao 위기관리 이론과 실천 2016 위기관리 이론과 실천 세미나발표논문집 Vol.2016 No.-

        Proceed with work of emergency education in elementary school is the basis of enhancing the level of emergency management. Through the analysis and summary of related concepts to emergency education, the paper defined the concept of emergency education, With the basics of which to look deeply into the current situation and difficulties of the primary school to push emergency education in our country from the aspect of the government, society and schools. Then, the paper put forward the path optimization of the primary school to push emergency education from the aspect of perfecting laws and regulations, facilitating social participation, standardizing the education content, and making evaluation mechanism.

      • Suppressive Effect of Sinomenine Combined with 5-Fluorouracil on Colon Carcinoma Cell Growth

        Zhang, Ji-Xiang,Yang, Zi-Rong,Wu, Dan-Dan,Song, Jia,Guo, Xu-Feng,Wang, Jing,Dong, Wei-Guo Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.16

        It is reported that sinomenine (SIN) and 5-fluorouracil (5-FU) both are effective for colon cancer, but their cooperative suppressive effects and toxicity remain to be clarified in detail. This study aimed to determine suppressive effects and toxicity of sinomenine (SIN) plus 5-fluorouracil (5-FU) on LoVo colon carcinoma cells in vitro and in vivo. CCK-8, Hoechst 33258 staining and an annexin V-FITC/PI apoptosis kit were used to detect suppressive effects. Western blotting was applied to investigate the essential mechanism underlying SIN and 5-FU-induced apoptosis. SIN or 5-FU or both were injected into nude mice, and then suppressive effects and side effects were observed. SIN plus 5-FU apparently inhibited the proliferation of LoVo cells and induced apoptosis. Moreover the united effects were stronger than individually (p<0.05). The results of annexin V-FITC/PI staining and Hoechst 33258 staining showed that the percentage of apoptotic cells induced by SIN and 5-FU combined or alone was significantly higher than the control group (p<0.05). Expression of Bax and Bcl-2 was up-regulated and down-regulated respectively. SIN or 5-FU significantly inhibited effects on the volume of tumour xenografts and their combined suppressive effects were stronger (p<0.05). No obvious side effects were observed. It was apparent that the united effects of SIN and 5-FU on the growth of colorectal carcinoma LoVo cells in vitro and in vivo were superior to those using them individually, and it did not markedly increase the side effects of chemotherapy.

      • KCI등재

        The New Ecosystem of Cross-border E-Commerce among Korea, China and Japan Based on Blockchain

        Xiang-Dong Shen,Xi Chen,Ran Ji,Ren-Hong Wu 한국무역학회 2020 Journal of Korea trade Vol.24 No.5

        Purpose - The purpose of the study is to propose a theoretical framework of cross-border e-commerce ecosystems based on blockchain technology. The ecosystem includes five systems, namely, crossborder supply chain intelligent system, cross-border logistics system, cross-border payment system, cross-border product quality traceability system and cross-border customs supervision system. Design/methodology - This study firstly derived the main improvement factors for the new ecosystem based on blockchain through prior research and expert interviews on cross-border e-commerce. Then explored the use of virtue of decentralization, anti-counterfeiting traceability, consensus mechanism, smart contract and other means of the core technology of blockchain to overcome the bottleneck of cross-border e-commerce development among Korea, China, and Japan. Finally, proposed valuable implications in both theoretical and practical perspectives. Findings - As a result, we combined with the problems existing in cross-border e-commerce among Korea, China and Japan, this paper proposes a solution based on blockchain. On this basis, it constructs a cross-border e-commerce ecosystem among these three countries, including five systems. In addition, we discuss the main problems existing in the current blockchain, such as low transaction concurrency, security loopholes, and inconsistent standards, the corresponding countermeasures are proposed from the technical level, security level and industry standards. Originality/value - This study is the first to apply the blockchain technology to solve the cross-border e-commerce problems in Korea, China and Japan, which is of pioneering significance in both literature and practice. Block chain technology is in the ascendency. This study provides technical solutions for promoting the development of cross-border e-commerce import and export trade between Korea, China and Japan.

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