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- 저자 : ( Javier De A Fuentea ) (검색결과 1 건)
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( Mariso Rodrigueza ),( Ruben Puertaa ),( Jose Uis Amasa ),( Ucla Gonzaeza ),( Tamara Gondara ),( Aexandra Arcaa ),( Uis Novoaa ),( Ana Sanjurjoa ),( Javier De A Fuentea ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: The aim of this study was to evaluate the risk of developing neoplastic processes in patients admitted for idiopathic venous thromboembolic disease (VTED). Methods: All patients admitted in our hospital in 2007 and 2008 diagnosed with VTED were included. Those that died during their hospitalization and those diagnosed with cancer before or during the thrombotic event were excluded. Multiple variables were analyzed including all clinical and laboratory factors considered as a risk for developing VTED. Using the primary care and specialist electronic medical records, we identifi ed the patients that were diagnosed with cancer in the period after being admitted for VTED (from hospital admission to July, 2014). Results: Of a total of 347 patients admitted with VTED in 2007 and 2008, 165 were excluded for presenting a history of cancer or a diagnosis of cancer in the moment of the thrombotic event or those who died during their hospitalization. Of the remaining 182 patients, 104 presented idiopathic VTED, with a median age of 75 years (range: 28 - 94), 54.7% were women. 11.6% of the patients with idiopathic VTED were diagnosed of cancer after discharge from the hospital, and 2.9% of the patients were diagnosed with secondary VTED (OR 4.4: CI 95% 0.95 - 20.7%; P=0.04). The median of months of evolution from the thrombotic event to the diagnosis of cancer was 41 (range: 8 - 70). The most frequent localization of the neoplastic process was gastric and prostatic (18% in each case), and the most frequent histological type was adenocarcinoma (63%). Conclusions: The development of cancer is frequent in patients with previous idiopathic VTED (11.6%), with a higher incidence than those with secondary VTED. Periodic clinical monitoring is important to make early diagnoses of tumor process after a thrombotic event.
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