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여드름양 발진에서의 말라쎄지아 포자 검출 빈도에 관한 연구
박장규,이웅재,김연수,서영준,김경호,이증훈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2
Steroid acne and pityrosporum folliculitis have similar clinical manifestations. So it was not casy to do differential diagnosis of these two diseases. We have tried to find out the different points between these diseases in clinical characteristics, positive rate of the malassezia spores, and their response to antifungal agents. We studied 21 patients with acneiform eruptions which were distinct from acne vulgaris. Patients were divided into two groups by steroid treatment history. Among 21 patients, 6 were administered steroid just before eruption and 15 were free from steroid within 6 months. We have examined malassezia spores with 10% KOH/Parker blue black ink mount from papules, pustules and comedones according to the patients skin lesions. The malassezia spores detected in 5 paticnts(83.3%) in the former and 9 patients(60%) in the latter. In malassezia folliculitis, the frequency of which showed above the (3+) score of malassezia spore under microscopy was higher than in steroid acne. Mean duration of the disease was 70.4 weeks in latter group, which was longer than 5.2 weeks of the former group. And there were some differences between two groups in the distribution of the lesions. Mean treatment duration was same in two groups (4 wks, 3.5 wks). Steroid acne patients would be treated better with antifungal agents than with acne regimens.
자극성 물질이 첩포시험 결과에 미치는 영향에 대한 연구
박장규,이우재,김경훈,서기범,이증훈 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2
We studied the effects of irritants on the positive patch test sites in 6 volunteers. We firstly performed the patch test with 2, 4, 6, 8, 10% sodium lauryl sulfate on the back of 22 volunteers. Allergens (thimerosal, mercury ammonium chloride) were applied in duplicate, and 24 hours later they were removed and sodium lauryl sulfate was applied for a further 24hours to one set of patches. Response of allergen alone were measured at 24 hours, 48 hours, 72 hours, 120hours, 140hours and the degree of inflammation of the other site(allergen + irritant) was graded 30 minutes, 24, 48 and 72 hours later according to International Contact Dermatitis Research Group. The results were as follows 1. Twenty volunteers(90.9%) showed irritation sign on the patch sites with 6% sodium lauryl sulfate. 2. In the results of patch test in 6 cases with positive allergen sites, 5 cases showed the similar results with those of previous patch test (reproducibility = 83 %) 3. When we assessed the patch test results according to ICDRG, the results of patch tests after application with irritants on previous positive allergen slites did not show stronger responses than those of positive allergen alone 4. The results of patch test after application with irritants on previous negative allergen did not show erythema. It seems that the effect irritant application of lower concentration than irritant dose not influence the response to the allergen concentration than to cause erythema, on the response of allergen
알레르기 피부 반응 검사시 판독 시간에 따른 팽진의 크기 변화
박장규,윤소영,이웅재,서기범,이증훈 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.2
There have been several positive criteria for skin prick test, which has been most commonly used in the diagnosis of allergic diseases. Among them, comparing wheal size induced by allergen to that induced by histamine is logical for criteria of skin prick test positivity. We measured the wheal sizes induced by histamine and various causative allergens with five minutes interval, from 5 minutes to 40 minutes, and compared of the time which the wheal size of both reached at peak. The followings were the summary of the findings. 1. Maximal sizes of wheals induced by histamine reached at 12 minutes in average. 2. Maximal sizes of wheals induced by allergens reached at 15 minutes in average. 3. There was no statistical difference between the time of maximal size of wheal induced by histamine and causative allergen.
Suppression of the NF-<i>k</i>B signalling pathway by ergolide, sesquiterpene lactone, in HeLa cells
Chun, Jae Kwang,Seo, Dong-Wan,Ahn, Seong Hoon,Park, Jae Hyun,You, Jueng-Soo,Lee, Chang-Hee,Lee, Jae Cheol,Kim, Yong Kee,Han, Jeung-Whan Pharmaceutical Society of Great Britain 2007 Journal of pharmacy and pharmacology Vol.59 No.4
가축분뇨 소화효율 증대를 위한 병합혐기성소화 특성 평가
정재훈 ( Jae-hoon Jeung ),김도영 ( Do-yong Kim ),정우진 ( Woo-jin Chung ),장순웅 ( Soon-woong Chang ) 한국폐기물자원순환학회(구 한국폐기물학회) 2021 한국폐기물자원순환학회 춘계학술발표논문집 Vol.2021 No.-
본 연구에서는 가축분뇨의 혐기성소화 효율을 증대시키기 위해 농업부산물 및 폐사축을 혼합한 병합 혐기성 소화에 대한 연구를 수행하였다. 연구는 BMP test의 형태로 수행되었으며, 각 원료의 혼합 비율별 바이오가스 발생량 및 메탄수율을 산정하여 소화효율을 평가하였다. 가장 높은 효율을 나타낸 것은 0.84 ㎥CH<sub>4</sub>/kgVS로 세 가지 원료가 균등하게 섞인 혼합비율에서 나타났으며, 타 혼합 원료에서도 가축분뇨 단일 소화와 비교하여 메탄수율이 1.03-1.29배 증가한 것으로 확인되었다.
정재훈 ( Jae-hoon Jeung ),이시진 ( Si-jin Lee ),정성엽 ( Seong-yeob Jeong ),( Nguyen Dinh Duc ),박헌수 ( Hun-su Park ),김정환 ( Jung-hwan Kim ),장순웅 ( Soon-woong Chang ) 한국폐기물자원순환학회(구 한국폐기물학회) 2017 한국폐기물자원순환학회 춘계학술발표논문집 Vol.2017 No.-
화석연료의 고갈로 인한 고유가 상황과 온실가스에 의한 지구온난화가 가시화 되면서 재생 가능한 에너지 개발과 자원의 효과적인 이용을 통한 자원순환사회 구축, 나아가 친환경적인 사회구현이라는 목표를 달성하기 위하여 선진국을 중심으로 환경과 에너지 문제를 해결하기 위한 연구가 진행되어 왔다. 이러한 전망을 토대로 국가적 부담을 최소화하고 실리를 추구할 수 있는 적극적이고 능동적인 대처방안을 강구할 필요성이 절실한 시점이다. 최근 신재생에너지의 확충과 기후변화 협약에 대한 적극적인 대응이 요구됨에 따라 단순 매립되던 폐기물을 에너지로 전환하여 처리하는 방식이 각광받으며 정부 계획 하에 적극적으로 추진되고 있다. 이러한 대응의 일환으로 1990년대 후반에는 유렵을 중심으로 연성에너지 체제에 부합하면서 지방자치단체 지역 공동체, 지역 주민들의 에너지 생산 활동 참여를 중시하는 지역에너지 체제가 대안으로 제시되었다. 에너지자립마을은 화석연료에 대한 의존도가 낮으며 지속가능한 마을과 유사한 것으로, 환경문제와 미래에너지 문제를 함께 고려한 개념으로 마을에서 발생되는 자원을 최대한 이용하고, 그 자원을 순환시키는 마을로 이해될 수 있다. 국내에서 2009년부터 농림수산식품부, 환경부, 지식경제부 등 정부부처가 합동으로 각종 바이오매스를 이용하여 에너지 자립형 마을 시범사업을 추진하면서 축산 바이오매스를 이용하는 바이오가스화 기술은 농촌 지역에 도입할 수 있는 가장 실행 가능한 기술로 평가받고 있다. 본 연구에서는 농촌형 에너지자립마을에서 발생될 수 있는 다양한 유기성폐기물을 대상으로 혼합 원료의 특성과 병합 혐기성소화의 효율을 평가하기 위하여 biochemical methane potential test(BMP test)를 진행하였다. 또한, 본 연구를 바탕으로 혐기성소화와 C/N비의 관계를 알아보고자 하였다.
정재훈 ( Jae-hoon Jeung ),이시진 ( Si-jin Lee ) 한국폐기물자원순환학회 2021 한국폐기물자원순환학회지 Vol.38 No.6
In this paper, we studied the efficiency of reducing sulfur inhibition during anaerobic digestion using biochar. The study was conducted using a batch test called the biochemical methane potential test in which various concentrations of Na2S were injected to determine the effects of sulfur. This experiment used leached food wastewater as the feedstock, and the composition of the experiment was divided into three sets; In Set 1, only Na2S was injected except for control, based on sulfur concentration (20-1,000 mg/L). In Set 2, biochar (BC, 5 g/L) were additionally injected to the Set 1 conditions. For comparison, FeCl<sub>3</sub> (24 g/ L) was injected together with Na<sub>2</sub>S in Set 3. The experiment indicated that overall the concentration of H<sub>2</sub>S in the generated biogas was significantly lower than that of other sets in Set 3 (injected with FeCl<sub>3</sub>). Furthermore, the concentration of H2S in Set 2 (injected with biochar) was found to be lower than that of Set 1 in the low-concentration range of Na<sub>2</sub>S. However, there was no significant difference from Set 1 in the high concentration range of Na<sub>2</sub>S. This result indicates that biochar can reduce the inhibition of sulfur; however, the efficiency decreases as the concentration increases. Furthermore, Set 3 yielded lower methane compared to the other sets, where the lowest biogas yield and methane yield were found to be 200+Fe in Set 3 as 0.046 m<sup>3</sup>/kgVS and 0.021 m<sup>3</sup>/kgVS, respectively. On the other hand, the highest biogas yield and methane yield were found to be 25+BC in Set 2 as 0.308 m<sup>3</sup>/kgVS and 0.166 m<sup>3</sup>/kgVS, respectively. This result indicates that Fe can reduce the effects of sulfur; however, it cannot enhance the efficiency of biogas production. Meanwhile, biochar has been seen to enhance both sulfur control and biogas production efficiency and hence can be used as a valuable material.