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( Young Jin Lee ),( Heung Yeol Kim ),( Chun Jun Lee ),( Wong Yu Kim ),( Ijo Jeong ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.98 No.-
This retrospective study evaluated bone mineral density (BMD) in premenopausal invasive cervical cancer patients with concurrent chemoradiation (CCRT). We retrospectively analyzed the BMD of spinal bone and the femur in 16 invasive cervical cancer patients treated with CCRT. All BMD was measured by dual-energy X-ray absorptiometry. For a 1-to-2 matched case-control study, 32 patients with benign uterine myoma whose age and body mass index are consistent with the case group were selected. All of the patients and control women had reached their menopause. The lowest BMDof patients treated with CCRT for invasive cervical cancer was significantly lower (p<0.05) than those of control women. The serum levels of calcium and phosphate were not significantly different between the patients with cervical cancer and control women. Age, height, body weight and body mass index were not significantly different between the two groups. Our study results suggest that invasive cervical cancer patients treated with CCRT have a lower BMD, resulting in an increased risk of osteoporosis.