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RISS 인기검색어
- 검색키워드
- 저자 : ( Hyoju Ham ) (검색결과 3 건)
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Ham, Hyoju,Lee, Bo-In,Oh, Hyun Jin,Park, Se Hwan,Kim, Jin Su,Park, Jae Myung,Cho, Young Seok,Choi, Myung-Gyu Korean Association for the Study of Intestinal Dis 2017 Intestinal Research Vol.15 No.4
<P>Celiac disease (CD) is an immune-mediated enteropathy and is a rare disease in Asia, including in Korea. However, the ingestion of wheat products, which can act as a precipitating factor of CD, has increased rapidly. CD is a common cause of malabsorption, but many patients can present with various atypical manifestations as first presented symptoms, including anemia, osteopenia, infertility, and neurological symptoms. Thus, making a diagnosis is challenging. We report a case of CD that mimicked amyotrophic lateral sclerosis (ALS). The patient was a sexagenary man with a history of progressive motor weakness for 2 years. He was highly suspected as having ALS. During evaluation of his neurological symptoms, esophagogastroduodenoscopy (EGD) was performed because he had experienced loose stools and weight loss for the previous 7 months. On EGD, the duodenal mucosa appeared smooth. A biopsy revealed severe lymphoplasma cell infiltration with flattened villi. His serum endomysial antibody (immunoglobulin A) titer was 1:160 (reference, <1:40). Finally, he was diagnosed as having CD, and a gluten-free diet was immediately begun. At a 4-month follow-up, his weight and the quality of his stool had improved gradually, and the neurological manifestations had not progressed.</P>
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( Hyoju Ham ),( Bo-in Lee ),( Hyun Jin Oh ),( Se Hwan Park ),( Jin Su Kim ),( Jae Myung Park ),( Young Seok Cho ),( Myung-gyu Choi ) 대한장연구학회 2017 Intestinal Research Vol.15 No.4
Celiac disease (CD) is an immune-mediated enteropathy and is a rare disease in Asia, including in Korea. However, the inges tion of wheat products, which can act as a precipitating factor of CD, has increased rapidly. CD is a common cause of malab sorption, but many patients can present with various atypical manifestations as first presented symptoms, including anemia, osteopenia, infertility, and neurological symptoms. Thus, making a diagnosis is challenging. We report a case of CD that mim icked amyotrophic lateral sclerosis (ALS). The patient was a sexagenary man with a history of progressive motor weakness for 2 years. He was highly suspected as having ALS. During evaluation of his neurological symptoms, esophagogastroduodenos copy (EGD) was performed because he had experienced loose stools and weight loss for the previous 7 months. On EGD, the duodenal mucosa appeared smooth. A biopsy revealed severe lymphoplasma cell infiltration with flattened villi. His serum endomysial antibody (immunoglobulin A) titer was 1:160 (reference, <1:40). Finally, he was diagnosed as having CD, and a gluten-free diet was immediately begun. At a 4-month follow-up, his weight and the quality of his stool had improved gradually, and the neurological manifestations had not progressed. (Intest Res 2017;15:540-542)
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Impact of Fatty Liver on Acute Pancreatitis Severity
Yoon, Seung Bae,Lee, In Seok,Choi, Moon Hyung,Lee, Kyungjin,Ham, Hyoju,Oh, Hyun Jin,Park, Se Hwan,Lim, Chul-Hyun,Choi, Myung-Gyu Hindawi 2017 Gastroenterology Research and Practice Vol.2017 No.-
<P><I>Aim</I>. Acute pancreatitis is typically a mild disease, but some patients develop severe courses. Fatty liver changes are seen in patients with acute pancreatitis, but its clinical significance has not been well-studied. We aimed to investigate the relationship between fatty liver and the severity of acute pancreatitis. <I>Methods</I>. Unenhanced CT images of patients with acute pancreatitis were retrospectively reviewed by a radiologist, and mean hepatic and splenic attenuation was measured in Hounsfield units (HU). Fatty liver was defined as mean hepatic/splenic HU < 1. <I>Results</I>. Among 200 patients, fatty liver was found in 67 (33.5%) and nonfatty liver in 133 (66.5%). Compared with patients without fatty liver, the severity of pancreatitis and levels of serum C-reactive protein were higher in fatty liver patients. The prevalence of local complications, persistent organ failure, and mortality were also higher in patients with fatty liver. Even after adjusting for age, sex, body mass index, and cause of pancreatitis, fatty liver was significantly associated with moderately severe or severe acute pancreatitis. <I>Conclusions.</I> Fatty liver may play a prognostic role in acute pancreatitis. Fatty liver could be incorporated into future predictive scoring models.</P>
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