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        Impaired Gallbladder Motility and Increased Gallbladder Wall Thickness in Patients with Nonalcoholic Fatty Liver Disease

        ( Yasar Colak ),( Gulcin Bozbey ),( Tolga Erim ),( Ozge Telci Caklili ),( Celal Ulasoglu ),( Ebubekir Senates ),( Hasan Huseyin Mutlu ),( Banu Mesci ),( Mehmet Sait Dogan ),( Guralp Tasan ),( Feruze Y 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2016 Journal of Neurogastroenterology and Motility (JNM Vol.22 No.3

        Background/Aims Nonalcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease worldwide. Along with the increase in the incidence of NAFLD and associated obesity, an increase in gallbladder disease (GD) has been noted. This has led to the identification of a new disease entity called fatty GD. There is a gap in the literature on the dynamics of gallbladder function in patients with NAFLD. Methods An observational case-control study, a total of 50 patients with biopsy proven NAFLD without gallbladder stone/sludge and 38 healthy comparison subjects were enrolled. Fasting, postprandial gallbladder volumes (PGV), gallbladder ejection fraction (GEF), and fasting gallbladder wall thickness (FGWT) were measured by real-time 2-dimensional ultrasonography. Results Fasting gallbladder wall thickness, fasting gallbladder volumes and PGV were significantly higher in patients with NAFLD than control subjects (P < 0.001, P = 0.006, and P < 0.001, respectively). Gallbladder ejection fraction was significantly lower in the NAFLD group than the controls (P = 0.008). The presence of NAFLD was an independent predictor for GEF, PGV, and FGWT. Also, steatosis grade was an independent predictor for GEF, and GEF was significantly lower in the nonalcoholic steatohepatitis (NASH) subgroup than the controls. Conclusions Gallbladder dysfunction and increase in gallbladder wall thickness exists in asymptomatic (without stone/sludge and related symptoms) patients with NAFLD and are useful in identifying fatty GD. Measurement of these variables in NAFLD patients may be useful in identifying those at higher risk for GD. (J Neurogastroenterol Motil 2016;22:470-476)

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        Effect of Interaction between Market Orientation and Learning Orientation on Marketing Capabilities: Comparison of Korean and Malaysian IT Firms

        페루즈 이모모프(Imomov Feruz),신택현(Tack-Hyun Shin) 동국대학교 경영연구원 2020 경영과 사례연구 Vol.42 No.1

        본 연구의 목적은 한국과 말레이시아 두 국가의 IT 업체를 대상으로 시장지향성, 학습지향성 및 조직성과의 하나인 마케팅 역량 간의 인과관계를 비교연구의 관점에서 밝혀보려는데 있다. 이 같은 연구목적을 달성하기 위해 저자들은 세 개의 가설을 세우고 이의 검증을 시도하였다. 한국의 경우 9개의 상호작용 유형 가운데 6개의 상호작용이 유의한 것으로 나타난 반면, 말레이시아의 경우는 아무런 상호작용 효과가 나타나지 않았다. 이 같은 연구 결과는 두 나라의 자본주의 성숙도와 환경적응 패턴에서 명확한 차이가 있음을 의미하는 것이다. The main purpose of this study is to comparatively highlight the causality among major constructs such as Market Orientation, Learning Orientation, and Marketing Capabilities as one kind of essential Organizational Performance in IT firms of two countries, Korea and Malaysia. To attain this purpose, the authors formed three hypotheses and testified them. In the case of Korea, six types of interaction among 9 kinds of interaction pattern proved to be significant. On the other hand, Malaysia showed no interaction effect on all types of pattern. This result means there exists apparent differences in the stages of capitalistic maturity and in the pattern of environmental adaptation in two countries.

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