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RISS 인기검색어
- 검색키워드
- 저자 : ( Edward J Lincoln ) (검색결과 2 건)
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Security Implications of the United States-Japan Economic Relationship
( Edward J Lincoln ) 한국국방연구원 1993 The Korean Journal of Defense Analysis Vol.5 No.2
This article considers the strategic implications of the US-Japan strategic relationship. The motivation for this analysis is the frequently expressed concern that the end of the Cold War might allow bilateral economic disputes to spin out of control, thereby damaging the security relationship as well. The Cold War period did involve a primarily strategic definition of the economic relationship, and it did involve some effort to contain or suppress economic tensions. However, the conclu- sion of the analysis is that powerful economic incentives exist for continuing the satisfactory resolution of disputes. Within that process, considerable noise and tension will remain, given the nature of the bargaining process. The outcome, though, ought to be continued im- provement in market access in Japan. This will strengthen commitment to the strategic relationship, and should also make Japan`s neighbors more comfortable since they will benefit from increased market access as well.
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Naiyer, Afzal J.,Shah, Jayesh,Hernandez, Lincoln,Kim, Soo-Youl,Ciaccio, Edward J.,Cheng, Jianfeng,Manavalan, Sanil,Bhagat, Govind,Green, Peter H.R. Mary Ann Liebert 2008 Thyroid Vol.18 No.11
<P>BACKGROUND: Individuals with active celiac disease (CD+) have an increased incidence of thyroid dysfunction, which improves on a gluten-free diet (CD-). We investigated whether tissue transglutaminase-2 IgA antibodies (anti-TGase II) present in sera of patients with celiac disease react with thyroid tissue and possibly contribute to thyroid disease. METHODS: Serum from 40 active celiac patients taken before a gluten-free diet (CD+), 46 patients on a gluten-free diet (CD-), 40 normal controls (NC), and 25 with Crohn's disease (CROHN) was used. All sera were screened for antithyroperoxidase antibodies (TPO-AB) and thyroglobulin antibodies (TG-AB), and indirect immunofluorescence (IIF) was performed on primate thyroid tissue sections using TPO-AB- and TG-AB-negative sera. RESULTS: IIF with thyroid seronegative, anti-TGase II-positive CD+ sera (n = 23) demonstrated staining of thyroid follicular cells and extracellular matrix, in an identical pattern with monoclonal anti-human TGase II antibody. Evidence of TGase II as the antigen in thyroid tissue was supported by elimination of the IIF pattern when sera were depleted of anti-TGase II by pretreatment with human recombinant TGase II. No staining of thyroid tissue was observed when sera from CD+ patients that were negative for TGase II antibodies, or sera from NC subjects were used. Thyroid antibodies were found in 43% of CD+ patients, significantly higher than NC and CROHN patients (p < 0.0001). In addition, a positive correlation was observed between anti-TGase II and TPO-AB titers (p = 0.0001; r = 0.63). CONCLUSIONS: Anti-TGase II antibodies bind to TGase II in thyroid tissue, and titers correlate with TPO antibody titers. These findings suggest that anti-TGase II antibodies could contribute to the development of thyroid disease in celiac disease.</P>
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