http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : ( Dongxia Qiu ) (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
Tao Shao,Dehong Bai,Mingzhu Qiu,Yu Li,Qiankun Zhang,Ziyu Xue,Shijie He,Dongxia Zhang,Xibin Zhou 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.108 No.-
Facile synthesis of more dendritic and uniform Pt-based nanostructures with carbon materials couldgreatly reduce cost and increase Pt utilization for methanol oxidation reaction (MOR) in direct methanolfuel cell (DMFC). This study reports a novel one-pot method to fabricate AgPt nano-pompons (AgPt NPs)with the guidance of N-GQDs through AA reduce the precursor of Ag and Pt. Morphology characterizationdescribes N-GQDs as morphology guiding and dispersing agents to regulate the dendrite formation ofnano-pompons. Under the optimized conditions, the AgPt NPs (Ag1Pt2) display above 11 times improvementin electrocatalytic activity and higher stability for the MOR compared with Pt/C catalysts. Densityfunction theory (DFT) studies prove that the introduction of Ag can greatly enhance the adsorption of COon Pt and promote the transformation of CO to COOH. The facile synthetic method and excellent MORperformance endow AgPt NPs with great application prospect in DMFCs as an anode catalyst.
-
Physalin D inhibits RANKL-induced osteoclastogenesis and bone loss via regulating calcium signaling
( Ning Ding ),( Yanzhu Lu ),( Hanmin Cui ),( Qinyu Ma ),( Dongxia Qiu ),( Xueting Wei ),( Ce Dou ),( Ning Cao ) 생화학분자생물학회(구 한국생화학분자생물학회) 2020 BMB Reports Vol.53 No.3
We investigated the effects of physalin A, B, D, and F on osteoclastogenesis induced by receptor activator of nuclear factor кB ligand (RANKL). The biological functions of different physalins were first predicted using an in silico bioinformatic tool (BATMAN-TCM). Afterwards, we tested cell viability and cell apoptosis rate to analyze the cytotoxicity of different physalins. We analyzed the inhibitory effects of physalins on RANKL-induced osteoclastogenesis from mouse bone-marrow macrophages (BMMs) using a tartrate-resistant acid phosphatase (TRAP) stain. We found that physalin D has the best selectivity index (SI) among all analyzed physalins. We then confirmed the inhibitory effects of physalin D on osteoclast maturation and function by immunostaining of F-actin and a pit-formation assay. On the molecular level, physalin D attenuated RANKLevoked intracellular calcium ([Ca(2+)](i)) oscillation by inhibiting phosphorylation of phospholipase Cγ2 (PLCγ2) and thus blocked the downstream activation of Ca2+/calmodulindependent protein kinases (CaMK)IV and cAMP-responsive element-binding protein (CREB). An animal study showed that physalin D treatment rescues bone microarchitecture, prevents bone loss, and restores bone strength in a model of rapid bone loss induced by soluble RANKL. Taken together, these results suggest that physalin D inhibits RANKL-induced osteoclastogenesis and bone loss via suppressing the PLCγ2-CaMK-CREB pathway. [BMB Reports 2020; 53(3): 154-159]
ScienceON
KISS연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
