Incisional Hernia in Adult Liver Transplant Recipients

( Ji Soo Lee ),( Kyeong Sik Kim ),( Chan Woo Cho ),( Kyo Won Lee ),( Gyu-seoung Choi ),( Jong Man Kim ),( Choon Hyuck David Kwon ),( Jae-won Joh ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

Aims: Incisional hernia is one of the complication following abdominal operation. Patients undergoing liver transplantation have a high risk of developing an incisional hernia because of immunosuppression. The purpose of this study is to review incisional hernia cases after liver transplantation and to identify the risk factors for hernia formation. Methods: We retrospectively reviewed and analyzed the medical records of the ninety-four incisional hernia patients after liver transplant recipients from January 2000 to December 2015 in single center institution. Results: 1463 underwent adult liver transplantation during the study period. 94 Incisional hernia patients were found among them. The overall incisional hernia rate was 6.4 %. Mean age was 54 years old and 76.6 % were men. No significant difference was observed for sex, diagnosis, smoking, alcohol, albumin, Child-Pugh score, MELD score, intensive care unit stay, hepatorenal syndrome, ventilator, spontaneous bacterial peritonitis, diabetes, bile leakage, wound problems between patients with incisional hernia and patients without incisional hernia. The characteristics of patients with incisional hernia showed old recipient, more body weight, higher body mass index, living donor recipient compared with patients without incisional hernia. Hypertension, tuberculosis, rejection, postoperative complication event before hernia were significant risk factor (p<0.05). Conclusions: Present study identifies the risk factors for incisional hernia. Surgeons should strive to reduce the risk of incisional hernia after adult liver transplantation.

Nutrient Balances, Food Security and Fe rtilize r Raw Materials

David Manning 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

Development and Validation of an Attitudinal-Profiling Tool for Patients With Asthma

Aileen David-Wang,David Price,조상헌,James Chung-Man Ho,Chong-Kin Liam,Glenn Neira,Pei-Li Teh,REcognise Asthma and LInk to Symptoms and Experience 대한천식알레르기학회 2017 Allergy, Asthma & Immunology Research Vol.9 No.1

Purpose: To develop a profiling tool which accurately assigns a patient to the appropriate attitudinal cluster for the management of asthma. Methods: Attitudinal data from an online survey of 2,467 patients with asthma from 8 Asian countries/region, aged 18-50 years, having had ≥2 prescriptions in the previous 2 years and access to social media was used in a discriminant function analysis to identify a minimal set of questions for the Profiling Tool. A split-sample procedure based on 100 sets of randomly selected estimation and validation sub-samples from the original sample was used to cross-validate the Tool and assess the robustness of its predictive accuracy. Results: Our Profiling Tool contained 10 attitudinal questions for the patient and 1 GINA-based level of asthma control question for the physician. It achieved a predictive accuracy of 76.2%. The estimation and validation sub-sample accuracies of 76.7% and 75.3%, respectively, were consistent with the tool’s predictive accuracy at 95% confidence level; and their 1.4 percentage-points difference set upper-bound estimate for the degree of over-fitting. Conclusions: The Profiling Tool is highly predictive (>75%) of the attitudinal clusters that best describe patients with asthma in the Asian population. By identifying the attitudinal profile of the patient, the physician can make the appropriate asthma management decisions in practice. The challenge is to integrate its use into the consultation workflow and apply to areas where Internet resources are not available or patients who are not comfortable with the use of such technology.

유기식품 시장의 확대를 위한 소비자 기대 충족 요건

Pearson David,Jung Man-Chul 한국유기농업학회 2012 韓國有機農業學會誌 Vol.20 No.4

The world’s food production systems are becoming an area of great concern for both human and ecological health. Research has identified that one of the greatest threats to sustainability is conventional industrial agricultural systems and the high energy and material cost they require to function. The organic food movement is contributing as promising alternative to the current dominant model. Over the last 50 years it has developed into the most visible brand for a healthier and more environmentally sustainable food system. However, to achieve its full potential there are still a number of hurdles which must be overcome to make organic products a more viable and appealing option for consumers. This paper provides an overview of key research that has been conducted on why consumers are buying organic products, what they are buying and what is preventing them from purchasing more. It concludes that the key challenge is for the organic food movement to convince existing consumers of the superior ‘value’ of its products. In addition there are a number of methodological issues associated with analysing the market for organic products as well as issues of limited distribution, intermittent availability and high prices that are currently preventing increases in sales. Recognition and management of these barriers could contribute to more effective targeted research into consumer food purchasing motivations and subsequently the development of more sophisticated marketing strategies that assist in maintaining integrity with consumers and fending off challenges from conventional as well as other complementary food systems such as local food movement. And finally to achieve these market growth strategies the organic food movement will need to cope with its diverse constituency - ranging from global corporates through to local production and consumption - and provide attractive opportunities to individuals and business at all stages in supply chain whilst retaining credibility with government to ensure ongoing policy support.

Can the model for end-stage liver disease score replace the indocyanine green clearance test in the selection of right hemihepatectomy in Child-Pugh class A?

Jong Man Kim,Choon Hyuck David Kwon,Jae-Won Joh,Jae Berm Park,Joon Hyeok Lee,Gaab Soo Kim,Sung Joo Kim,Seung Woon Paik 대한외과학회 2014 Annals of Surgical Treatment and Research(ASRT) Vol.86 No.3

Purpose: To identify the correlation of the model for end-stage liver disease (MELD) scores with the assessment of the risk of hepatic function after hemihepatectomy in patients with hepatocellular carcinoma (HCC) related to hepatitis B virus (HBV). Methods: A case-control study was performed based on data for 141 consecutive patients who underwent curative right hepatic resection between January 2006 and June 2010. Results: All patients were Child-Pugh class A. The mean age of the patients was 50 years (range, 29?73 years). The group included 114 men (80.9%) and 27 women (19.1%). The distribution of MELD scores (median, 7; range, 6?14) and indocyanine green retention rate at 15 minutes (ICG-R15) (median, 9.2%; range, 1.1%?19.5%) showed no significant correlation (P = 0.615). Only one perioperative death (0.7%) occurred within 30 days, which was the result of liver failure by hepatic artery dissection during the Pringle maneuver. Hepatic dysfunction occurred in 25 patients (17.7%) after liver resection. In multivariate analysis, male gender, increased HBV DNA level, and elevated serum aspartate transaminase level were significantly related with hepatic dysfunction. Tumor size and satellite nodule were closely associated with tumor recurrence in HBV-related HCC after right hemihepatectomy and satellite nodule was a predisposing factor for mortality in those patients. Conclusion: MELD score does not accurately predict hepatic function after right hemihepatectomy in patients with resectable HBV-related HCC. MELD scores were not correlated with the ICG-R15 values in patients with Child-Pugh class A.

Predictability of Common Stock Pricess in the Korean Stock Market

김재만(David Jai Man Kim) 한국경영학회 1982 經營學硏究 Vol.11 No.-

Portable X-Ray Fluorescence Spectrometry for Elemental Soil Characterization

David Weindorf,Laura Paulette,Titus Man 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

Integration of Adults with Mental Handicaps into the Community of Hong Kong

David Ping-Pui,Tak-wah yeung,Man-hung Ngan,Chau-Kiu Cheung,Kin-yin Li BK21 Project Force of Special Education Deagu Univ 2001 Journal of Asia-Pacific Special Education Vol.1 No.3

The exten and factors of the integration of adults with mental handicaps into the community of Hong Kong is an uncharted area for rigorous investigation. To conduct the investigation, this study surveyed a representative sample of 692 adults, aged 15 or above, from the end of 1998 through early 1999. The survey sapmle sufficient numbers of adults of the three levels of handicaps, mild(n=234), moderate(n=337), and severe grades(n=121). To measure community intergration, the study employed a comprehensive set of scales, which demonstrated satisfactory reliability. With data weighted to best represent the population adults with mental handicaps in Hong Kong, the study found that being accepred was the highest.

Primary hepatic neuroendocrine carcinoma

Jong Man Kim,Se Yeong Kim,Choon Hyuck David Kwon,Jae-Won Joh,Jae Berm Park,Joon Hyeok Lee,Sung Joo Kim,Cheol-Keun Park 한국간담췌외과학회 2013 한국간담췌외과학회지 Vol.17 No.1

A 67-year-old woman was admitted to our hospital under suspicion of a hepatic tumor, which had been previously diagnosed to be an adenocarcinoma by fine needle aspiration. Computed tomography and magnetic resonance imaging revealed a large tumor measuring 9 cm in diameter in Couinaud’s hepatic segments 4, 5, and 8. We diagnosed the patient to have primary liver cancer, and suspected intrahepatic cholangiocarcinoma preoperatively. We performed a central hepatectomy. According to the immunohistochemical findings of the resected specimen, the tumor was diagnosed to be a primary neuroendocrine carcinoma in the liver. The patient is presently alive without recurrence at 3 months after hepatic resection.

HCC : PE-069 ; C-reactive protein is closely associated with prognosis in hepatocellular carcinoma with pathological portal vein invasion

( Jong Man Kim ),( Choon Hyuck David Kwon ),( Jae Won Joh ),( Jae Berm Park ),( Sung Joo Kim ),( Suk Koo Lee ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1

Background: Hepatocellular carcinoma (HCC) has a high predilection for portal vein invasion. The objective of this study was to investigate clinicopathologic characteristics and outcomes of HCC patients with pathological portal vein invasion. Methods: We retrospectively reviewed the clinicopathologic data and outcomes of 83 HCC patients with portal vein invasion and 1056 patients without portal vein invasion who underwent liver resection. Results: Increased serum alkaline phosphatase (ALP) levels, increased maximum tumor size, and intrahepatic metastasis were predisposing factors for portal vein invasion by multivariate analysis. The median disease-free survival and overall survival of HCC patients with portal vein invasion was 4.5 months and 25 months, respectively. The 1-year, 2-year, and 3-year disease-free survival rates were 30.6%, 26.1%, and 21.2%, respectively, and overall survival rates in HCC patients with portal vein invasion were 68.6%, 54.2%, and 41.6%, respectively. The first detection site was lung in HCC patients with portal vein invasion and liver in HCC patients without portal vein invasion. C-reactive protein (CRP) was a significant independent predictor of tumor recurrence in HCC with portal vein invasion after surgery. Conclusions: Increased ALP levels, increased maximum tumor size, and intrahepatic metastasis were independent predictors of portal vein invasion in HCC. CRP level was closely associated with the predisposing factor of tumor recurrence in HCC patients with portal vein invasion after surgical resection, and lung metastasis was common.