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- 저자 : ( Damir Zhenalayev ) (검색결과 1 건)
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Pediatric Liver Transplantation Experience in Kazakhstan
( Gari Kuttymuratov ),( Damir Zhenalayev ),( Dulat Mustafinov ),( Aiymkul Ashimkhanova ) 대한간학회 2016 춘·추계 학술대회 (KASL) Vol.2016 No.1
Aims: The aim is to analyze the first results of pediatric liver transplantation experience. Currently in Kazakhstan on the waiting list for liver transplantation there are approximately 22 children various congenital or acquired liver pathologies. Most of the children with end stage liver disease need a donor organ transplant before the age of 1 year old. During the period from 2012 to 2015 at National Research Center for Maternity and Child in Astana, there are total of 6 pediatric living donor liver transplantations were performed in Kazakhstan. In all cases, the left lateral segment of the donor liver was allocated for transplantation. Age of recipients ranged from 5 months up to 6 year old. The donors are close relatives of the recipient, their age ranged from 24 to 36 years. In 5 out of 6 cases in children under the age of 1 year old the etiology of liver cirrhosis was biliary atresia. In a 6 y.o. child the underlying cause of cirrhosis was autoimmune hepatitis. All liver transplantation performed with the participation of foreign experts from India, Turkey, and The Republic of Belarus. Methods: Prospective study from the start of the first pediatric liver transplantation. Results: Postoperative complications were not observed in donors. One child under the age of 5 months had a PO-complication as hepatic artery thrombosis (HAT). The surgical actions to fix the vascular damage were unsuccessful and the child was taken by sanitary aviation to hospital in Istanbul, Turkey, where he had another liver transplantation from a living donor. In the remaining five recipients there were no complications observed, and they discharged from the hospital. Due to the severe shortage of donors, the mortality rate of children on a waiting list is up to 54%. Conclusions: The lack of experience of local transplant surgeons in carrying out highly advanced surgeries in young children, forcing patients to carry out similar operations in foreign clinics by governmental funding or on their own expense. The most common surgery for liver transplantation Kazakhstani children held in South Korean hospitals, Germany, Turkey, India. On behalf of our colleagues and patients we want to thank our friends - colleagues from South Korea, Turkey, India, for their help and support in the development of transplantation in the Republic of Kazakhstan.
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