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      • Analysis of the Cases with Carcinoma Gallbladder (CA GB) in a Tertiary Level Hospital of Nepal

        ( Romi Dahal ),( Bika Lghimire ),( Prasan Kansakar ),( Ramesh Singh Bhandari ),( Paleswan Joshi Lakhey ) 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1

        Aims: Gallbladder cancer (GC) is a relatively rare disease in some parts of world but is common in countries like Chile, Japan India and Nepal. Nepal stands as one of the five countries with the highest mortality. Methods: A retrospective analysis of the consecutive operated and non-operated admitted cases of GC in TUTH from 2018 to 2019 was done. Patient demographics, disease characteristics, diagnostic modalities and various curative and palliative treatment variables were analyzed. Results: Of the 59 patients, there were 33 females (56%) who outnumbered the 26 males(44%) with a male to female ratio of 0.7:1. The median age at diagnosis was 56 years with younger group (<60 years) comprising 62.7% of the disease. Among all, the most common presenting symptom was abdominal pain followed by jaundice. Onset of first symptoms was within mean duration of 40 days (SD 37.45 days). USG and CT availability (100%) lead to preoperative diagnosis in majority. Curative resection (extended cholecystectomy) was done in 16 (27%). The most common anatomic location of mass was fundic followed by neck. Pathological examinations revealed most cases of adenocarcinoma. Of the advanced metastatic Ca GB in 30% of cases, the most common site of metastasis was liver. Mean survival after diagnosis in advanced cases was 4.5 months. Conclusions: CA GB is more common in Nepal, more among females and younger patients often presenting with pain abdomen and jaundice. Most are advanced at the time of diagnosis Radical surgery can be offered to few patients where the outcome seems reasonably good.

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