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RISS 인기검색어
- 검색키워드
- 저자 : ( Abay Jumanov ) (검색결과 2 건)
- 무료
- 기관 내 무료
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The First Experience of Radiotherapy on the Pancreas Cancer in KazIOR
( Oleg Trushenko ),( Marat Kuzikeyev ),( Abay Jumanov ),( Zhanat Pyssanova ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1
Aims: Despite the improvement of special treatment methods, the 5-year survival rate according to different authors is 1-10%. In 2016 in Kazakhstan, the number of people who fell ill at the PCa was 1028, while the one-year mortality rate was 65,1%. Radiation therapy (RT) is one of the treatment options for ma lignant neoplasm of the pancreas. Our purpose is to improve the treatment results of patients with PCa. Methods: The method of IMRT was applied in 8 patients with adenocarcinoma of the third stage. 5 of them (62.5%) are primary patients without any treatment, 3 (37.5%) - after not radical operations. At the end of the course of treatment with a patient with PCa, the quality of life did not worsen. There are no early radiation reactions of high toxicity (RTOG 3-4). The evaluation of the quality of the conducted RT was carried out by Multispiral Computed Tomography (MSCT) with contrast enhancement (bolus + per. os). Results: The best results are observed in a patient whose tumor size decreased from 6.1x5.1x3.8 cm to 4.1x3.8x3.7 cm in 1 month after radiation therapy. As a result, in 5 primary patients after 2,0 Gy per fraction to 55-60 Gy observed partial regression of the lesion, 3 patients underwent postoperative radiation ther apy for prevention of disease recurrence (they are follow-up). Conclusions: The application of the technique of intensively modulated radiotherapy in patients with malignant neoplasm of the pancreas, increases access to new methods of treatment, and improves the quality of life and the survival rate.
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Management of a Surgical Treatment of Patients with Pancreatic Cancer
( Marat Kuzikeyev ),( Timur Nasritdinov ),( Abay Jumanov ),( Sergey Lashkul ),( Innara Turkpenova ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1
Aims: In this study our purpose is analysis of retrospective patients with I-III stages which went to the surgery and postoperative chemo - and radiotherapy in Kazakh Scientific Research Institute of Oncology and Radiology. Methods: Totally 64 patients between 2009 and 2016 underwent surgical treatment of pancreatic cancer and follow-up. Which of them: pancreatoduodenal resection was performed in 37 patients, corpocaudal resection in 12 patients, distal pancreas resection in 12 patients, total pancreatectomy performed to 3 patients. Resequence in pancreatic head cancer was 25.5%, with carcinoma of the body and tail - 10.1%. Results: Postoperative mortality for pancreatoduodenal resection was 8.7% (in the last 5 years - 3.5%), distal resection was 13.3%. The average life expectancy after pancreatoduodenal resection was 17.4 months, pancreatectomy - 8 months, distal subtotal pancreas resection - 11.2 months. Three years after pancreatoduodenal resections, 14.7% lived, and the 5-year survival rate was 4.4%. After palliative surgery, the average life expectancy was 5.2 months. The best long-term results were observed when applying a complex and combined treatment. In distal pancreas resection postoperative use of SBRT/IMRT radiation therapy or induced chemotherapy, give almost same results. In this way, improvement of the treatment results of pancreatic cancer is possible with early diagnosis and applying of complex and combined treatment. Patients should be classified and treated with a multidisciplinary approach at specialized centers. Conclusions: In this way, improvement of the treatment results of pancreatic cancer is possible with early diagnosis and applying of complex and combined treatment. Patients should be classified and treated with a multidisciplinary approach at specialized centers.
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