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- 저자 : ( Abay Baigenzhin ) (검색결과 1 건)
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Portal Vein Thrombosis after Liver Transplantation: Prevention and Treatment
( Zhaksylyk Doskaliyev ),( Marlen Doskali ),( Abay Baigenzhin ),( Nurbek Ilyassov ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1
Aims: Among complications after liver transplantation the vascular causes of graft dysfunction remains as a devastating complication and its challenging clinical condition requires a multidisciplinary approach for management. Methods: From January 2013 to January 2017, 38 LDLTs were performed in our center. Operation procedures were performed by standard methods in donor and recipients. In all donors right hepatectomies were performed. Risk factors and variables associated with the transplant and the post-transplant period were analyzed. Results: At a median follow up of 3 years, both the patient and graft survival were 82%. The main causes of transplantation were primary biliary cirrhosis (50%), viral hepatitis (30%) and other liver diseases. The median age of the recipients at the time of LDLT was 43.9±17.2 (19-65 years). Recipients average hospital stay was 30±5 days (23-38 days, median 30 days) found. Vascular and biliary complications were the leading cause of reoperation, graft loss and retransplantation. Conclusions: Portal vein thrombosis is an awkward problem to treat after liver transplantation because a different portal inflow is difficult to establish. We successfully applied the heparin-based treatment in 3 patients, but graft loss were found in 2 patients. It is reliable to use a local delivery of thrombolytic therapy compare to systemic therapy because of a high risk of systemic bleeding in post-liver transplant patients. Survival rate depends on presence of PVT in cirrhotic liver before surgery.
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