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      • SCOPUSKCI등재

        Pheochromocytoma 의 마취관리 1예 보고

        조용호,김태성,길호영,진상호,윤영준,최병석 대한마취과학회 1989 Korean Journal of Anesthesiology Vol.22 No.6

        The anesthetic management of patients with pheochromocytoma presents many difficult problems, such as hypertension, cardiac arrhythmias, and hypotension. A 21 year-old male underwent resection of pheochromocytoma under general anesthesia with isoflurane and fentanyl. Hypertensive crisis during induction of anesthesia and surgical manipulation of the tumor were managed with phentolamine and sodium nitroprusside drips. Anesthesia was maintained wtih nitrous oxide : oxygen, 50% : 50%, isoflurane, 0.5-2% and supplemented with fractional doses of fentanyl and vecuronium for muscular relaxation. We also used propranolol for the cardiac arrhythmia. An endotracheal semi-closed circle absorption technique with controlled ventilation was employed. Fentanyl does not release histamine, and has stable hemodynamics. Isoflurane has also advocated on the grounds that arrhythmias are less esaily provocated by circulating catecholamines than with other volatile agents, and has been shown to be a satisfactory agent. Vecuronium does not provoke catecholamine release, does not release histamine, has no autonomic effects at clinical plasma concentrations, and is clearly the neuromuscular blocking agent of choice in this case. Optimal pre-operative preparation, smooth induction of anesthesia, adequate alveolar ventilation, proper cardiovascular control, and good communication between surgeon and anesthesiologist are most important for the anesthetic management of pheochromocytoma.

      • KCI등재

        丁酉再亂 포로 실기 속 한시에 투영된 화자 의식

        조용호 한국고전연구학회 2019 한국고전연구 Vol.0 No.45

        이 논문은 정유재란 시의 포로 실기에 포함된 한시에 투영된 화자 의식을 고찰한 것이다. 방법상으로는 시⋅공간의 변화에 따라 세 시기로 나누고, 그 기간에 지어진 시들에서 화자의 의식이 변모하는 추이를 살폈다. 대상은 일기 형태의 글에 포함된 시로 한정했는데, 그것은 실기에 포함된 시에서 화자의 기억이 가장 적게 굴절된다고 생각했기 때문이다. 피로 전후부터 일본의 거류지에 도착하기까지 지어진 시는 일부 인사들의 기록에만 나온다. 그 가운데 강항의 시에는 사적인 감상이나 고뇌는 최소화되고 담담하게 상황을 감내하는 절제심이 뚜렷이 나타났다. 정희득과 정호인이 피란 중에 쓴 시에는 미래에 대한 불안감, 도와주지 않는 자연에 대한 원망과 안타까움이 스며있다. 일본에 있을 때 지어진 시 가운데, 노인의 것에는 온전히 귀국하여 임금께 충성하고 일본에 복수하겠다는 의식이 드러난다. 강항은 일본에 억류돼 있을 때 지은 시에서도 늘 충성심을 전면에 내세웠다. 그럼에도 불구하고 그는 자신의 이력이 훗날 시비를 불러일으킬 것을 예상하며, 환국한 뒤에는 조용히 은거할 생각을 드러냈다. 정경득 일족은 오직 생환하는 것만을 지상과제로 여겼다. 그들의 시에는 오직 고향과 부모를 그리는 의식만이 담겨 있다. 환국하는 과정에 지어진 시 가운데, 노인의 것에는 부모형제에 대한 걱정과 근심이 깊이 투영되어 있었다. 강항의 시에는 성은이 포로 신세인 자신에게까지 미친 데 대한 감개무량함과, 이로 인해 갖게 된 충성심과 절의가 뚜렷이 드러났다. 정경득 일행은 돌아오는 과정에 대마도에서 6개월 동안이나 발이 묶이게 되는데, 그 결과로 시에도 초조함과 절망감이 깊이 스며있었다. 특히 밤에 우는 새에게 실향인의 의식을 깊이 가탁하기도 하였다. 이런 방식의 연구 결과를 통하여, 피로자들의 삶과 의식을 훨씬 입체적으로 이해할 수 있었다. 이것은 일기 속에 기록된 편지 등의 산문이나 대화 자체만으로 피로자의 의식을 검토하는 것과는 다른 시각과 가치를 지닌 것이라는 점에서 분명한 의의를 지닌다고 하겠다. This paper examines the speaker’s consciousness projected at Chinese poetry, which was included in the true record literature written by Korean prisoners during Jeong-yu-jae-ran. For this purpose, I divided into three periods according to the change of time and space, and I observed the change of the speaker’s consciousness in the poems written in each period. The object of examining was confined to the poems included in the literature of diary type, because it was thought that the memory of the speaker was refracted the least in the poems included in the true record. The poems, which were written from the time before and after becoming captive until the arrival at the Japanese settlement, were only recorded by some people. Among them, the poems of Gang-hang minimized the private sentiments and anguish and distinctly expressed a moderation that endured the situation in a disinterested attitude. The poems that were written by Jeong-Hee-deuk and Jeong-Ho-in during the eruption were filled with anxiety about the future, resentment, and regret about nature that did not help them. Among the poems that were composed in Japan, No-In’s poetry represented the consciousness that he wanted to be loyal to the king and take revenge on Japan after returning home. When Gang-Hang was detained in Japan, he always brought his loyalty to the fore of the poems. Nonetheless, he anticipated that his past would invoke dispute in the future, so he revealed thought that he would live in seclusion after returning home. Jeong-Gyeong-deuk’s family regarded only the return as the supreme task. Their poetry showed solely yearning for parents and home. Among the poems that were written during the process of returning home, No-In’s poetry had a profound reflection of worries and anxieties about his parents and brothers. Gang-Hang clearly expressed infinite deep gratitude for loyal favor he received during the captivity and revealed the loyalty and fidelity to the king. Jeong-Gyeong-Deuk and his group were deprived of means of transit for six months in Daema-do(Tsushima in Japan) during the return journey. As a result, the poetry was deeply immersed in irritability and despair. In particular, they personified the consciousness of the displaced by the bird crying at night. Through the results of this study, I could understand the life and consciousness of the captive from more diverse angles. This study has a clear significance in that it has a different perspective and value that it has examined the consciousness of prisoners not only by a prose, such as a letter, or conversation but also by poetry in the literature of diary type.

      • KCI등재
      • 갯기름나물의 근(根)과 경엽(莖葉)의 면역 및 항암 활성 비교연구

        조용호,Cho, Yong-Ho 대한한방피부미용학회 2005 대한한방피부미용학회지 Vol.1 No.1

        This study compared the activity of the aerial part of P. japonicum with its root in order to examine the possibility of the medicinal use of the aerial part, which has not been used as medicine, in substitute for the root that has traditionally been used as medicine. For this purpose, the author measured the proliferation of Human $CD4^-$ T cells, which are related to immunity, the differentiation of HL-60 cells, and the contents of IL-6, IgE and $TNF-{\alpha}$ and compared their anti-cancer effect on Hep3B and A549 cells. The results of this study are as follows: 1. As for Human $CD4^-$ T cells, $1.0\;g/{\ell}$ methanol extract from the aerial part promoted the proliferation of the cells 1.8 times higher while $1.0\;g/{\ell}$ methanol extract from the root did by 1.76 times higher compared to the control group. 2. As for HL-60 cells, methanol extract and water extract from the aerial part showed differentiation 1.14 times higher and 1.12 times higher respectively while methanol extract and water extract from the root did 1.14 times higher and 1.07 times higher compared to tile control group. 3. Cell density was highest on Day 4 of culture in all samples, Methanol extracts from the aerial part and the root showed activities of $7.9{\times}10^3\;cells/m{\ell}$ and $7.5{\times}10^3\;cells/m{\ell}$ respectively, and water extracts from the aerial part and the root did activities of $5.3{\times}10^3\;cells/m{\ell}$ and $6.1{\times}10^3\;cells/m{\ell}$. 4. The secretion of IL-6 was highest on Day 4 of culture. Methanol extracts from the aerial part and the root showed secretions of $6.7{\times}10^{-3}\;pg/cells/m{\ell}$ and $7.2{\times}10^{-3}\;pg/cells/m{\ell}$ respectively, and water extracts from the aerial part and the root did secretions of as high as $7.0{\times}10^{-3}\;pg/cells/m{\ell}$ and $6.0{\times}10^{-3}\;pg/cells/m{\ell}$. 5. As for the production of IgE, water extract from the root effectively inhibited the product at $1,000\;{\mu}g/m{\ell}$, methanol extract from the root at $10\;{\mu}g/m{\ell}$ and $100\;{\mu}g/m{\ell}$, water extract from the aerial at $1,000\;{\mu}g/m{\ell}$, and methanol extract from the aerial part at $1,000\;{\mu}g/m{\ell}$. 6. According to the result of measuring the content of $TNF-{\alpha}$, methanol extracts from the root and the aerial part showed inhibition effect at $10\;{\mu}g/m{\ell}$, $100\;{\mu}g/m{\ell}$ and $1,000\;{\mu}g/m{\ell}$. 7. As for liver cancer cell Hep3B, $1.0\;g/{\ell}$ methanol extracts from the root and the aerial part showed inhibition effects of 78% and 70% respectively, and $1.0\;g/{\ell}$ water extracts from the root and the aerial part did inhibition effects of 56% and 59%. 8. As for lung cancer cell A549, $1.0\;g/{\ell}$ methanol extracts from the root and the aerial part showed inhibition effects of 75% and 70% respectively, and $1.0\;g/{\ell}$ water extracts from the root and the aerial part did inhibition effects of 48% and 45%. The results of this study presented above show that the aerial part of P. japonicum has immunizing and anti-cancer effects as high as its root, which has commonly been used as medicine. There should be more in-depth research on the aerial part of P. japonicum in the future.

      • 뇌 Glutamic-Oxaloacetic Transaminase Isozyme에 미치는 Cycloheximide의 영향

        조용호,Cho, Yong-Ho 생화학분자생물학회 1972 한국생화학회지 Vol.5 No.1

        Mouse 뇌의 glutamic-oxaloacetic transaminase (GOT) isozyme에 미치는 cycloheximide의 영향을 관찰하였다. GOT의 supernatant (extramitochondrial) isozyme 은 cycloheximide (1 mg/kg)를 복강내 주입한 후 2시간~4시간에 약 20~30% 억제하였으며 그 후로는 점차 활성이 정상으로 회복되었다. 이에 대하여 mitochondrial isozyme은 cycloheximide에 의하여 아무런 영향도 받지 아니하였다. Cycloheximide는 뇌 GOT-isozyme 중 가용성 분획의 GOT 동위효소단백의 생합성을 선태척으로 억제하였으며, 기존된 supernatant isozyme이 mitochondria 것에 비하여 조절적 기능이 보다 더 잘 발휘 될 수 있음을 시사하였다. Of the two isozymes of glutamic-oxaloacetic transaminase (GOT) in mouse brain, only the supernatant (extramitochondrial) isozyme was inhibited 20~30% at 2 to 4 hours after the intraperitoneal injection of cycloheximide (1 mg/kg) into mice. By contrast, the mitochondrial one was not affected at all by cycloheximide. It was suggested that the diminution of the supernatant isozyme activity might be caused by the inhibition of the biosynthesis of the enzyme GOT. And the supernatant isozyme of the brain GOT is more regulatory than the mitochondrial one.

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