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Peng, Sheng,Yang, Qiu-Xia,Zhang, Tao,Lu, Ming-Jian,Yang, Guang,Liu, Zhen-Yin,Zhang, Rong,Zhang, Fu-Jun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.13
Aim: To investigate the efficacy and safety of lobaplatin-transcatheter arterial chemoembolization (TACE) combined with radioactive $^{125}I$ seed implantation in treatment of primary hepatocellular carcinoma (HCC). Methods: 75 patients with primary HCC were enrolled in the study, among them 43 receiving lobaplatin-TACE (TACE group) and 32 lobaplatin-TACE combined with $^{125}I$ seed implantation (TACE+$^{125}I$ group). After treatment, the local remission rates and postoperative complications of two groups were compared using the Pearson Chi-square test. Overall survival in the two groups was calculated using Kaplan-Meier survival curves and the differences were tested using Log-rank test. Results: There were 7 cases of complete response (CR), 13 of partial response (PR), 6 of stable disease (SD) and 17 of progressive disease (PD) in the TACE group, with 13 cases of CR, 9 of PR, 5 of SD and 5 of PD in the TACE+$^{125}I$ group. The disease control rates of TACE and TACE+$^{125}I$ group were 60.5% (26/43) and 84.4% (27/32), respectively, with a significant difference between them (P < 0.05). The survival rates at 6, 12 and 18 months in the TACE group were 100.0%, 81.8% and 50.0%, respectively, and those in TACE+$^{125}I$ group were 100.0%, 93.8% and 65.6%. The mean survival times in the TACE and TACE+$^{125}I$ groups were 19.5 and 22.9 months, respectively. There was a significant difference in the overall survival rate between two groups (P < 0.05). No serious complications were encountered in either group. Conclusion: Lobaplatin-TACE combined with $^{125}I$ seed implantation is favorable and safe for treatment of primary HCC.
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Kun Luo,Pengsheng Wang,Xiaoyan Lei,Yan Zhao 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.10
Model similarity experiment is an effective method to predict the vibration response of track-box girder structure under complex working conditions. In this paper, the coupling similarity relationship between the layers of the multilayer structure is deduced theoretically. In addition, according to the elasticity similarity law and the π theorem, a track-box girder coupling vibration model with a 10:1 geometric similarity ratio was designed. The influence of parameters on the system similarity was further discussed, including the density and elastic modulus of track plate, the stiffness of fastener and CA mortar layer. Finally, a scale track-box girder model was built. Based on the modal test and finite element method, the model design and the similarity relation between prototype and model were verified. The results show that the scale model can be employed to forecast vibrations for an elevated track bridge, and the vibration level under different working conditions can be inverted from the model test results in model design. When the geometry size of a certain structural layer in the direction of load is much larger than that of the other structural layers, the similarity relation derived from the material properties of the structural layer is approximately equal to the similarity of the system between the prototype and the scale model.
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An Integrated Simulation Method to Support Virtual Factory Engineering
Zhai, Wenbin,Fan, Xiumin,Yan, Juanqi,Zhu, Pengsheng Society for Computational Design and Engineering 2002 International Journal of CAD/CAM Vol.2 No.1
This paper presents a structure and architecture of an integrated simulation method (ISM) to meet the requirements of virtual factory engineering (VFE). Combining CAD, VR and discrete event simulation techniques, the ISM provides static and dynamic simulation functions for implementation of VFE throughout the lifecycle. The static simulation can be used to evaluate the factory layout. The dynamic simulation enables us to evaluate ergonomics of factory, process performance of production system, feasibility of production plan and operation of factory, and to train operators safely, which cover the whole VFE lifecycle. The principles of the key techniques of VFE, including virtual factory data management system (VFDMS), static and dynamic simulation, are also discussed. To demonstrate and validate the ISM, a case study has been carried out in an assembly factory.
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