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Celeste Manfredi,Pramod Krishnappa,Esaú Fernández-Pascual,Elena García Criado,Diego Rengifo,David Vázquez Alba,Joaquín Carballido,Davide Arcaniolo,Juan Ignacio Martínez-Salamanca 대한배뇨장애요실금학회 2022 International Neurourology Journal Vol.26 No.2
Purpose: To evaluate the preoperative and intraoperative risk factors for revision after artificial urinary sphincter (AUS) implantation in male patients with stress urinary incontinence (SUI). Methods: A retrospective analysis from a prospectively maintained database was performed. Male patients, with moderate-tosevere SUI, undergoing AUS implantation were included. All patients underwent placement of AMS 800. Cause of revision, type of revision, and time to revision were recorded. Multivariable analyzes were performed using a logistic regression to investigate the risk factors. Competing risk analysis according to Fine-Gray model was used to study time to event data. Results: A total of 70 patients were included. Revision surgery was performed in 22 of 70 patients (31.4%), after a median (interquartile range) time of 26.5 months (6.5–39.3 months). Overall, 19 of 22 repairs (86.4%) and 3 of 22 explants (13.6%) were recorded. Mechanical dysfunction, urethral erosion, urethral atrophy, and device infection were the causes of revision in 11 of 22 (50.0%), 6 of 22 (27.3%), 3 of 22 (13.6%), and 2 of 22 patients (9.1%). Vesicourethral anastomosis stenosis (P=0.02), urethral cuff size of 3.5 cm (P=0.029), and dual implantation (P=0.048) were independent predictors for revision. Vesicourethral anastomosis stenosis (P=0.01) and urethral cuff size of 3.5 cm (P=0.029) predicted a lower survival of the AUS. Conclusions: The vesicourethral anastomosis stenosis, urethral cuff size of 3.5 cm, and dual implantation are independent predictors for revision after AUS implantation. However, only the vesicourethral anastomosis stenosis and urethral cuff size of 3.5 cm predict a lower survival of AUS.
A Consensus based Rate Control Scheme for ATM Networks
Sabato Manfredi 제어·로봇·시스템학회 2012 International Journal of Control, Automation, and Vol.10 No.4
This paper is concerned with the design and validation of a consensus based rate control for the Asynchronous Transfer Mode (ATM) networks. A sufficient condition for network closed loop stability in the presence of multiple bottleneck and heterogeneous sources with different time delays is given and it is used for switch-controller parameters design. The stability condition and the resulting congestion control performance in terms of robustness to network uncertainties, fairness, link utiliza-tion and packet loss are validated by discrete packet simulator. Moreover, it ensured convergence of the queue length to the desired consensus steady-state value with resulting network queue balancing.
Evaluation of Refining Strategies for Combined use of Softwood and Eucalyptus Pulps in Papermaking
VAIL MANFREDI 한국펄프·종이공학회 2006 한국펄프종이학회 기타 간행물 Vol.- No.-
The paper discusses the combined use of softwood and eucalyptus kraft pulps in the production of printing and writing papers. Looking for process and paper quality optimization, refining pilot plant trails were carried to identify the effects of refining type (mixed or separate) and intensities (specific edge load), and also furnish composition (amount of each pulp in mixture) on final paper quality and process costs. The basic effects on pulp fibers were evaluated against paper quality properties, such as physical strengths, bulk, vessel picking, opacity and porosity, as well as the interactions with papermaking process, such as estimates of paper machine runnability, paper breaks and industrial refining control. The results show that the furnish composition and the type of refining has a significant effect on properties related with both final paper quality and total costs. The best alternative for printing and writing papers was identified for mixed refining, under the lowest refining intensity, and with the highest dosage of eucalyptus pulp.
Raphael Palmier Manfredi,Flávio de Andrade Silva 대한토목학회 2020 KSCE JOURNAL OF CIVIL ENGINEERING Vol.24 No.3
Fiber reinforced concrete (FRC) has been used for many different construction applications and many testing protocols have been developed to determine their mechanical behavior. The present paper focuses on the comparisons between four major standard mechanical tests used for FRC. Polypropylene fibers were used as reinforcement in volume ratios of 3 kg/m³, 6 kg/m³ and 10 kg/m³ in a self-consolidating high-strength concrete. The flexural beam tests according to American and European standards were carried on through a closed loop type of control. Comparisons include crack post-peak strength and energy absorption values. The European flexural beam test showed to be more precise for low ductile concretes (i.e., low fiber volume fractions). This is due to the notch and different methods used for instrumenting the specimen. The square panel test due to its boundary conditions showed much higher results with a deflection-hardening type of behavior. Since the frame comes into full contact with the specimen, that creates a more rigid material response. This response differs from the other three tests since their support conditions allow rotations and induces cracks to appear in determined locations.
Giuseppa Graceffa,Salvatore Vieni,Manfredi Magliulo,Iole Laise,Mario Latteri,Calogero Cipolla 대한갑상선-내분비외과학회 2020 The Koreran journal of Endocrine Surgery Vol.20 No.2
Purpose: Intraoperative neuromonitoring (IONM) of the recurrent laryngeal nerve (RLN) is a useful technique that can be applied to assess the nerve functionality at the end of the first side lobectomy in a planned total resection to prevent the bilateral injury of the RLN. Here we describe the process of informed consent of patients, who were subjected to a 2-stage thyroidectomy, and its effect on the patients willingness to be operated on as well as their consent rates. Methods: A retrospective observational study of patients, undergoing thyroidectomy with standardized IONM, was conducted from January 2019 to December 2019. All patients were preoperatively informed about the possibility of undergoing a 2-stage thyroidectomy. The outcome of this information was evaluated through a specific questionnaire that the patients were asked to fill in. Results: Eighty patients were initially included in the analysis. The treatment was discontinued in 8 patients, who were originally eligible to total thyroidectomy, due to the detection of a loss of signal in the electromyography. The analysis of the results of the questionnaires highlighted a high compliance of the patients with the expectation of a possible new intervention. Conclusion: Two-stage thyroidectomy proved to be a reliable surgical approach and appeared to be largely accepted by the patients.
Di Ludovico, M.,Balsamo, A.,Prota, A.,Manfredi, G. Techno-Press 2008 Structural Engineering and Mechanics, An Int'l Jou Vol.28 No.6
In the framework of the SPEAR (Seismic PErformance Assessment and Rehabilitation) research Project, an under-designed three storey RC frame structure, designed to sustain only gravity loads, was subjected, in three different configurations 'as-built', Fiber Reinforced Polymer (FRP) retrofitted and rehabilitated by reinforced concrete (RC) jacketing, to a series of bi-directional pseudodynamic (PsD) tests under different values of peak ground acceleration (PGA) (from a minimum of 0.20g to a maximum of 0.30g). The seismic deficiencies exhibited by the 'as-built' structure after the test at PGA level of 0.20g were confirmed by a post - test assessment of the structural seismic capacity performed by a nonlinear static pushover analysis implemented on the structure lumped plasticity model. To improve the seismic performance of the 'as-built' structure', two rehabilitation interventions by using either FRP laminates or RC jacketing were designed. Assumptions for the analytical modeling, design criteria and calculation procedures along with local and global intervention measures and their installation details are herein presented and discussed. Nonlinear static pushover analyses for the assessment of the theoretical seismic capacity of the structure in each retrofitted configuration were performed and compared with the experimental outcomes.
Giulia Ghiacci,Gallia Graiani,Francesca Ravanetti,Edoardo Manfredi,Carlo Galli,Antonio Cacchioli,Guido Maria Macaluso,Roberto Sala,Simone Lumetti 대한치주과학회 2016 Journal of Periodontal & Implant Science Vol.46 No.4
Purpose: The aim of this study was to present new a model that allows the study of the bone healing process, with an emphasis on the biological behavior of different graft-tohost interfaces. A standardized “over-inlay” surgical technique combined with a differential histomorphometric analysis is presented in order to optimize the use of critical-size calvarial defects in pre-clinical testing. Methods: Critical-size defects were created into the parietal bone of 8 male Wistar rats. Deproteinized bovine bone (DBBM) blocks were inserted into the defects, so that part of the block was included within the calvarial thickness and part exceeded the calvarial height (an “over-inlay” graft). All animals were sacrificed at 1 or 3 months. Histomorphometric and immunohistochemical evaluation was carried out within distinct regions of interest (ROIs): the areas adjacent to the native bone (BA), the periosteal area (PA) and the central area (CA). Results: The animals healed without complications. Differential morphometry allowed the examination of the tissue composition within distinct regions: the BA presented consistent amounts of new bone formation (NB), which increased over time (24.53%±1.26% at 1 month; 37.73%±0.39% at 3 months), thus suggesting that this area makes a substantial contribution toward NB. The PA was mainly composed of fibrous tissue (71.16%±8.06% and 78.30%±2.67%, respectively), while the CA showed high amounts of DBBM at both time points (78.30%±2.67% and 74.68%±1.07%, respectively), demonstrating a slow remodeling process. Blood vessels revealed a progressive migration from the interface with native bone toward the central area of the graft. Osterix-positive cells observed at 1 month within the PA suggested that the periosteum was a source of osteoprogenitor elements. Alkaline phosphatase data on matrix deposition confirmed this observation. Conclusions: The present model allowed for a standardized investigation of distinct graft-to-host interfaces both at vertically augmented and inlay-augmented sites, thus possibly limiting the number of animals required for pre-clinical investigations.