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Molecular Pathogenesis of Vibrio vulnificus
Gulig Paul A.,Bourdage Keri L.,Starks Angela M. The Microbiological Society of Korea 2005 The journal of microbiology Vol.43 No.1
Vibrio vulnificus is an opportunistic pathogen of humans that has the capability of causing rare, yet devastating disease. The bacteria are naturally present in estuarine environments and frequently contaminate seafoods. Within days of consuming uncooked, contaminated seafood, predisposed individuals can succumb to sepsis. Additionally, in otherwise healthy people, V. vulnificus causes wound infection that can require amputation or lead to sepsis. These diseases share the characteristics that the bacteria multiply extremely rapidly in host tissues and cause extensive damage. Despite the analysis of virulence for over 20 years using a combination of animal and cell culture models, surprisingly little is known about the mechanisms by which V. vulnificus causes disease. This is in part because of differences observed using animal models that involve infection with bacteria versus injection of toxins. However, the increasing use of genetic analysis coupled with detailed animal models is revealing new insight into the pathogenesis of V. vulnificus disease.
Preliminary Study of Utilizing Plastic Tubes as a Component of Continuum Robots
Denys Makarets,Gunwoo Noh,Keri Kim,Deukhee Lee 제어로봇시스템학회 2014 제어로봇시스템학회 국제학술대회 논문집 Vol.2014 No.10
Continuum robots, new class of dexterous and thin robots, can be applied in great variety of minimal invasive surgical operations. These robots consist of two parts: manipulator, also called active cannula, and control unit. Manipulators, which are composed of concentric precurved tubes(usually 2-3), commonly made from nitinol, can enter human body through small incisions or natural orifices and, after reconfiguration into more complex structure, guide surgical instruments to the target regions avoiding obstacles. In this paper, we propose to use plastic as the material for innermost tube. Variations in the shape of lab-made concentric precurved plastic tube prototypes after numerous extension-retractions are investigated. We also use kinematic model, based on beam mechanics, for capturing the end-effector tip position and the shape of the two manipulators (I ? manipulator is composed of one nitinol tube and one plastic tube prototype; II ? manipulator is composed of two nitinol tubes and one plastic tube prototype). The model predictions are compared with the experimental results. Preliminary results show that plastic tubes may have small radii of precurvature, and sustain extension-retraction without self-damage thus potentially can be used as a component of continuum robots.
Vinayak Adimule,Basappa C. Yallur,Rangappa Keri,Chinna Bathula,Sheetal Batakurki 대한금속·재료학회 2023 ELECTRONIC MATERIALS LETTERS Vol.19 No.3
The development of triple oxide semiconductor nanostructures (NS) with special optical window is critical for the optoelectronicsand the luminescent industry. The present article describes the synthesis of Sm x :Gd (1−x) @SrO (x = 0.4, 0.6, 0.8)NS by simple Coprecipitation method. The NS were characterized by X-ray powder diff raction (XRD), scanning electronmicroscopy (SEM), SEM–EDS (energy dispersive spectra), Fourier transform infrared (FT-IR), UV–visible, X-ray photoelectronspectroscopy (XPS), and Brunauer–Emmett–Teller analytical methods. The results of the powdered XRD patternrevealed the formation of mixed-phase of hexagonal crystal structure, with grain size between 62 and 78 nm. Redshift inoptical absorption spectra for the Sm 3+ doped Gd (1−x) SrO NS appeared when compared to Gd (1−x) SrO NS. Photoluminescence(PL) spectroscopy demonstrated broad deep defect levels in Sm x : Gd (1−x) SrO NS when compared to Gd (1−x) SrONS. PL studies of Gd 0.6 , SrO exhibited three emission peaks detected at 373.6 nm, 382.1 nm, and 392.7 nm when excited at325 nm. PL studies of Sm x : Gd (1−x) SrO NS (x = 0.8) showed four emission peaks appeared at 415 nm (violet), 472 nm (blue),532.1 nm (green) and 569.6 nm (yellow) due to f–f transition of Sm 3+ in 4f 5 confi guration. Higher values of dielectric constant(3.86 × 10 4 ), dielectric permittivity (10 3 –10 5 ) resulted for the Sm x :Gd (1−x) @SrO (x = 0.8) NS with negligibly small dielectricloss (< 0.03) when compared to Gd 0.6 SrO NS. The synthesised materials demonstrated excellent luminescence propertieswith good dielectric properties therefore these materials could be good candidates to be used as high-luminescent devices.
최태영(Taeyoung Choi),이수준(Soojun Lee),이우섭(Woosub Lee),김계리(Keri Kim),강성철(Sungchul Kang) (사)한국CDE학회 2014 한국 CAD/CAM 학회 학술발표회 논문집 Vol.2014 No.2
This paper presents an active cannula robot system and its development for microsurgery. The active cannula robot is composed of concentric precurved tubes in telescoped arrangement and controlled by translation and rotation of each tube. For practical implementation to the various microsurgery operations, a peculiar but undesirable phenomenon, bifurcation is investigated and tried to be managed to avoid the problem. For performance, the overall control system is improved on the point of processing speed and pose accuracy. The pose on the tip is measured by telecentric scope and its workspace is examined for reliable operation.
Yonghwan Moon,Jihoon Kim,Suhun Jung,Sang Kyung Kim,Jeongryul Kim,Keri Kim 제어로봇시스템학회 2022 제어로봇시스템학회 국제학술대회 논문집 Vol.2022 No.11
Due to the worldwide spread of COVID-19, each government invests many human resources and money in screening tests. The spread of the virus has led to the development of robots that track the location of specimen collection or drive directly through master-slave devices by installing special equipment on patients noses to reduce the physical burden on medical staff and prevent infection during screening tests. Sampling robots proposed in previous studies have a rather complicated specimen collection process or make it impossible to collect specimens when the patient cannot wear special equipment. Therefore, we propose a deep learning-based model that predicts the nasopharyngeal specimen sampling path without additional equipment. The test bench for the collection of learning datasets was configured, and the nasopharyngeal specimen sampling path was expressed using an augmented reality marker to learn the estimated value. In addition, we add weight factors to the proposed model to compare the root mean square error of the direction vector.