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Christopher Woodward,Josie Smith,Dean Acreman,Nagappan Kumar 한국간담췌외과학회 2019 Annals of hepato-biliary-pancreatic surgery Vol.23 No.2
Illicit use of androgenic anabolic steroids (AAS) is a known problem amongst certain groups including body builders and other athletes. Use of these drugs is thought to be high in some areas of South Wales. A number of adverse effects have been associated with use of AAS including the development of hepatic adenomas. There have been a handful of rare cases of the development of hepatocellular carcinoma following AAS use. We report two such cases presenting to the same surgical centre in South Wales within six months. We do this with reference to data from Public Health Wales, including the Harm Reduction Wales Needle and Syringe provision report, which indicate a particularly high rate of use of AAS in the surrounding area. We believe these cases are important from the public health point of view. They demonstrate a rare and not widely known about, but potentially fatal adverse effect of AAS, now becoming prevalent with the high use of these drugs. This is important for doctors to be aware of, but also could form the focus of a public health campaign targeted at AAS users.
Marcelo Lourenço Silva,Josie Resende Torres Silva,Wiliam Alves Prado 사단법인약침학회 2016 Journal of Acupuncture & Meridian Studies Vol.9 No.4
Preemptive analgesia involves introducing an analgesic before noxious stimulation. Electroacupuncture (EA) activates descending mechanisms that modulate nociceptive inputs into the spinal dorsal horn. This study evaluated whether preoperative EA is more effective than postoperative EA in reducing incision pain in rats. The nociceptive threshold to mechanical stimulation was utilized to examine the effects of an intraperitoneal injection of saline (0.1 mL/kg) or naloxone (1 mg/kg) on antinociception induced by a 20-minute period of 2-Hz or 100-Hz EA applied to the Zusanli (ST36) and Sanyinjiao (SP6) acupoints before surgical incision, or 10 minutes after or 100 minutes after surgical incision of the hind paw. The extent of mechanical hyperalgesia after the incision was significantly attenuated by the application of 100-Hz EA preoperatively, but not by its application at 10 minutes or 100 minutes postoperatively. By contrast, 2-Hz EA was effective against postoperative hyperalgesia when applied 10 minutes or 100 minutes after surgery but not when it was applied preoperatively. Only the effect of 2-Hz EA applied 10 minutes after surgery was sensitive to naloxone. The present study showed for the first time that 100-Hz EA, but not 2-Hz EA, exerts a nonopioidergic preemptive effect against postincision pain in rats.
Effect of Acupuncture at Tender Points for the Management of Fibromyalgia Syndrome: A Case Series
Jessica Lucia Neves Bastos,Josie Resende Torres Silva,Marcelo Lourenco Silva,Fernanda Lopes Buiatti de Araujo,Elisa Do´ria Pires 사단법인약침학회 2013 Journal of Acupuncture & Meridian Studies Vol.6 No.3
Background: Affecting more women than men, fibromyalgia syndrome (FMS) is a rheumatic disorder characterized by chronic, diffuse and widespread musculoskeletal pain, and its pathogenesis is still unknown. Among the recommended treatments, acupuncture (for its analgesic effects) is an effective option for reducing the pain sensitivity and improving quality of life. Therefore, this study aimed to investigate whether acupuncture at tender points could effectively manage FMS. Methods: Eight female patients, with a previous diagnosis of fibromyalgia, underwent an initial assessment involving pressure algometer measurements for pain tolerance and questionnaires [Fibromyalgia Impact Questionnaire (FIQ), Heath Assessment Questionnaire (HAQ), Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI)], followed by treatment. Over a 2-month period, acupuncture was performed once per week at five tender points, located bilaterally at the occipital bone, trapezius, rhomboid, upper chest and lateral epicondyle. At the end of treatment, the participants underwent a reassessment for a final review of the applied methods. Results: We observed a reduction in the pain threshold and sensitivity and improvement in the areas of anxiety and depression and quality of life, which were demonstrated using the FIQ, BDI and BAI but not the HAQ.
Le courriel chez les jeunes adolescents
Olga Volckaert-Legrier,Josie Bernicot,Alain Bert-Erboul 고려대학교 응용문화연구소 2013 에피스테메 Vol.0 No.9
The aim of this study was to determine the extent to which the linguistic signs used by adolescents in electronic mail (email) differ from those used in traditional written language. The study was conducted in French, a language with a deep orthography that has strict, addressee-dependent rules for using second person personal pronouns (unfamiliar and familiar forms). Data was collected from 80 adolescents ages 12 to 15 in a natural situation where they had to introduce themselves by email to two addressees, a same-age peer and a teacher. The adolescents were divided into two groups (expert / non-expert) according to their expertise in computer-mediated communication. The results showed that for adolescents, email constitutes a written-language register of its own. Moreover, in terms of adaptation to the addressee (pronoun use), the email register seems to follow the pragmatic rules of traditional spoken and written interaction. The observed differences between the CMC experts and non-experts suggest that the email communication register is acquired gradually. L’objectif de notre recherche est de mettre en évidence dans quelle mesure les marques linguistiques utilisées par des adolescents en courrier électronique (CÉ) s’écartent de la langue écrite traditionnelle. Le recueil de données est effectué avec 80 adolescents de 12 à 15 ans dans une situation naturelle où ils doivent se présenter par CÉ à deux interlocuteurs (un pair d’âge et un professeur). Les adolescents sont divisés en deux groupes selon leur expertise en CMO (expert/non expert). Les résultats montrent que chez des adolescents, le CÉ correspond à un registre spécifique de la langue écrite du point de vue des marques linguistiques orthographiques. Par ailleurs, ce registre respecte les règles pragmatiques de l’interaction traditionnelle orale ou écrite en termes d’adaptation à l’interlocuteur (utilisation des pronoms). Les différences entre les adolescents experts en CMO et non experts témoignent de l’apprentissage progressif de ce registre spécifique.
Marcelo L. Silva,Wiliam A. Prado,Josie R.T. Silva 사단법인약침학회 2012 Journal of Acupuncture & Meridian Studies Vol.5 No.1
This study examined whether or not the antinociceptive effect of 2- or 100-Hz electroacupuncture (EA) depends on the integrity of the retrosplenial cortex (RSC). Rats were taken for determination of tail-flick latency before and after injection of saline or 2%lidocaine (0.25 ml) into the retrosplenial cortex (RSC) bilaterally. Five minutes later, they were submitted to a 20-minute period of 2 Hz, 100 Hz, or sham EA at the Zusanli and Sanyinjiao acupoints bilaterally, and tail-flick latency was measured within 30 seconds after the end of stimulation and at 5-minute intervals for up to 30 minutes. EA at a frequency of either 2 or 100 Hz induced a strong and long-lasting inhibition of the tail-flick reflex in rats treated with saline (0.25 ml) injected into the RSC. The analgesia produced by 2-Hz EA lasted for a shorter time in lidocaine-treated rats. By contrast,RSC impairment did not change the analgesic effect of 100 Hz EA. The integrity of the RSC is implicated in the duration of analgesia induced by low-frequency EA but is not essential for the analgesic effects evoked by high-frequency EA.
Participation of Potential Transient Receptors in the Antinociceptive Effect of Pharmacopuncture
Argôlo Isabella de Paula Ribeiro,Parisi Julia Risso,Silva Josie Resende Torres da,Silva Marcelo Lourenço da 사단법인약침학회 2022 Journal of Acupuncture & Meridian Studies Vol.15 No.2
Background: Despite the widespread clinical use of acupuncture in painful situations, the use of this treatment should be further clarified. Nociception is mediated by the activation of nociceptors, such as transient receptor potentials (TRPs). The family of TRPs includes TRPV1, TRPM8, and TRPA1, which can be stimulated by substances such as capsaicin, menthol, and methyl salicylate, respectively. Objectives: This study aimed to investigate the role of TRPs in antinociception via the administration of agonists of these receptors in the Zusanli acupoint (ST36) in models of inflammatory, acute, and neuropathic pain. Methods: Male Wistar rats were used for this experiment. All rats received a subcutaneous injection of TRP agonists (capsaicin, menthol, or methyl salicylate) in ST36; saline was injected as control. Nociception was evaluated using the electronic mechanical threshold test and tail-flick test before the administration of complete Freund’s adjunct or chronic constriction injury of the sciatic nerve and after the administration of TRP agonists. Results: Nociception was found to be attenuated after treatment with TRP agonists. The administration of different doses (0.03, 0.3, and 3.0 µg/20 µL) of capsaicin, menthol, and methyl salicylate in the different pain models (neuropathic, inflammatory, and nociceptive) induced antinociception in most of the evaluated time points. Conclusion: Based on the findings, we suggest that the activation of TRPV1, TRPM8, and TRPA1 receptors results in the antinociceptive effect of the stimulation of the ST36 acupoint. Thus, TRP receptors may present a new therapeutic opportunity for the control of inflammatory and neuropathic pain.
Cabural, Aubrey M.,Catarig Dexter T.,Evangelista Marjory P.,Go Josie Lace Y.,Martillano Mary Hope T.,Banacia Alberto S. 대한전자공학회 2010 ICEIC:International Conference on Electronics, Inf Vol.1 No.1
In this paper, we have presented a system which performs automatic face detection and tracking using Motion Detection and Principal Component Analysis. The system was implemented with the use of a network camera VB-C50i and MATLAB 7.0. We divided the study into three (3) major stages. The first stage was the motion detection. After motion had been detected, face detection happened and then finally the detected face was tracked down. The first stage is motion detection. This was performed by setting a threshold for the maximum difference and used this threshold as an indicator for motion. The second stage for this system is face detection. When the system detected the image, the camera automatically captured the image. The captured image was then zoomed in and the possible face region was taken as input data. This possible face region underwent principal component analysis for face detection. After the principal component analysis detected the face, the image was cropped and zoomed in. The final stage is the tracking down of the face as analyzed in the first two stages. Once the system was able to track down the location of the face, it automatically displayed the detected face area. The whole system functioned in such away that it continued to loop every time a motion was detected. The whole system shows the efficiency and accuracy of automatic face detection and tracking with the use of principal component analysis.