Effects of Source of Supplemental Zinc on Performance, Nutrient Digestibility and Plasma Mineral Profile in Cashmere Goats

Jia, Wenbin,Zhu, Xiaoping,Zhang, Wei,Cheng, Jianbo,Guo, Cuihua,Jia, Zhihai Asian Australasian Association of Animal Productio 2009 Animal Bioscience Vol.22 No.12

This experiment was designed to evaluate the effects of source of supplemental zinc (Zn) on performance, nutrient digestibility and plasma mineral profile in Cashmere goats during the cashmere fiber growing period. Twenty-seven Liao Ning Cashmere wether goats (9-10 month of age; initial BW = 19.31${\pm}$0.32 kg) were fed a basal diet (containing 22.3 mg Zn/kg DM) with no supplemental Zn (control) or 20 mg of supplemental Zn/kg of DM from Zn sulfate ($ZnSO_{4}$) or Zn methionine (ZnMet) for 60 days including a 10-day metabolism trial. Average daily gain (ADG) (p<0.05) and gain:feed (G/F) (p<0.05) were increased by Zn supplementation, but no differences were noted between Zn sources (p>0.05). The length and diameter of cashmere fiber did not differ among treatments (p>0.05). Zn supplementation had no influence on digestibility of DM, CP, EE and NDF (p>0.05). However, ADF digestibility in the group supplemented with ZnMet was significantly higher than in other treatments (p<0.05). Plasma Zn was increased (p<0.05) and Cu tended to be decreased (p = 0.057) by Zn supplementation, but no differences were found between Zn sources (p>0.05). Plasma alkaline phosphatase activity (AKP) was improved by Zn supplementation (p<0.05) and was higher in the $ZnSO_{4}$ than the ZnMet group (p<0.05). Zn retention was increased (p<0.05) and apparent absorption rate was decreased (p<0.05) by Zn supplementation. The results indicate that supplementation of 20 mg Zn/kg DM either as $ZnSO_{4}$ or ZnMet in the basal diet containing 22.3 mg Zn/kg DM can improve growth performance in Cashmere goats, and effectiveness of the two sources is similar on performance measurements.

Chinese herbal medicine for myasthenia gravis: A systematic review and meta-analysis of randomized clinical trials

Zhu Si-jia,Wang Rui-ting,Yu Ze-yu,Zheng Ruo-Xiang,Liang Chang-Hao,Zheng You-you,Fang Min,Han Mei,Liu Jian-ping 한국한의학연구원 2022 Integrative Medicine Research Vol.11 No.2

Background: Myasthenia Gravis (MG) is a disorder of neuromuscular transmission bringing mild ocular weakness to severe generalized muscle weakness and disability. The conventional treatments have longterm side effects, and Chinese herbal medicines (CHM) have shown possible effect and safety for MG patients, but the existing evidence was not robust enough and the results were out of date. Methods: Searching for randomized controlled trials (RCTs) was conducted in 7 databases and clinical trial registries until July 2021. The Risk of Bias (ROB) 2 tool was used to assess the study quality and GRADE was used to assess the quality of whole evidence. Meta-analyses were conducted and the results were presented as risk ratio (RR) or mean difference (MD) with 95% confidence interval (CI). Results: Nineteen RCTs (1283 participants) testing 13 kinds of CHM with adequate randomization were included and six RCTs investigating Compound Huangqi were included in the meta-analyses. In addition to conventional treatment, nine CHMs reduced symptom scores of MG. Compound Huangqi plus conventional treatment (pyridostigmine bromide or prednisone or both) reduced the symptom scores compared with conventional treatment (MD=-3.56, 95%CI -4.86 to -2.26). Less adverse events happened in the CHM groups (3/247 in the CHM groups, 52/245 in the control groups, RR=0.13, 95%CI 0.06 to 0.30, 9RCTs, a total of 492 participants). The effect on quality of life was inconsistent. Conclusion: Nine CHMs could probably bring benefit for MG symptom improvement. Moderate to low certainty of evidence supported Compound Huangqi added-on conventional treatment probably bring extra benefit of improving MG symptoms. Adding CHMs could be safer than giving only conventional treatment. Study registration: The protocol was registered in PROSPERO (CRD42016032718).

关于"圈子"研究的现状与综述

Zhu Jia Li(朱嘉莉),Jin Hong(金虹) 대한경영교육학회 2016 경영교육저널 Vol.27 No.1

Explore the state of society can get information from the perspective of "Circles". And "Circles" is a social phenomenon existing between formal and informal organization. A comprehensive understanding of "Circles" can supply certain help to future research and enterprises with some theoretical support. This study looks through the domestic and foreign literatures, and make theoretical knowledge and research objects in arrangement. The results of this study show that the domestic scholars concentrate their studies on "Circles" of organization and Internet, while the foreign scholars pay attention on interpersonal relations state and psychological state of individual. The present researches lack of empirical research on "Circles" and how to make the best of mobile social network to do marketing activities is also a meaningful question. "圈子"是探究社会状态的一个角度, 它是一种社会现象, 存在于正式组织和非正式组织之间。对"圈子"的全面认识, 能给学者的未来研究提供一定帮助以及给企业实践提供理论支持。本研究通过查找国内外的相关文献, 梳理了"圈子"的理论知识体系及学者研究关注点。研究结果显示, 国内学者的研究关注点倾向组织和网络方面, 而国外的研究关注点更多的是人际状态以及个人心理状态。现有的研究对于"圈子"的实证研究较少, 并且企业或个人如何更好地利用移动社交平台中的圈子进行营销活动也是一个值得探讨的问题。

Phenylpropanoids and Lignanoids from Euonymus acanthocarpus

Jia Xian Zhu,Hui Zi Jin,Jie Ren,Jiang Jiang Qin,Xiangrong Cheng,Qi Zeng,Fei Zhang,Shi Kai Yan,Wei Dong Zhang 대한약학회 2012 Archives of Pharmacal Research Vol.35 No.10

A new phenylpropanoid derivative (1), along with five phenylpropanoids (2-6), two monoepoxy lignans (8-9), one bisepoxy lignan (10), two cyclolignans (11-12), six neolignans (7, 13-17), two mixed lignan-neolignans (18-19), two lignan glycosides (20-21), and four flavonolignans (22-25), were isolated from the stems and twigs of Euonymus acanthocarpus. Compounds 2-3, 6-8, 12,and 14-25 were obtained from Celastraceae family for the first time, and compounds 5 and 9 were isolated from Euonymus genus for the first time. All the compounds were tested for cytotoxicity against SK-OV-3 and MCG-803 human tumor cell lines. Compounds 3, 10, 12, and 18 showed weak cytotoxicity against SK-OV-3 cell line, and compounds 3-4, 10-13, and 19 showed weak cytotoxicity against MCG-803 cell line.

Aldol-Like Carbon-Carbon Condensation for Pyridyl Substituted Chlorins

Jia-Zhu Li,Young Key Shim,Bing-Cun Cui,Jin-Jun Wang 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.7

Association of Single Nucleotide Polymorphisms in Exon 6 Region of BMPRIB Gene with Litter Size Traits in Sheep

Jia, Cunling,Li, Ning,Zhao, Xingbo,Zhu, Xiaoping,Jia, Zhihai Asian Australasian Association of Animal Productio 2005 Animal Bioscience Vol.18 No.10

The objective of this study was to investigate polymorphisms of BMPRIB (bone morphogenetic protein type IB receptor) gene and its effect on litter size traits in sheep. Three populations including 101 Small Tailed Han sheep, 79 Poll Dorset and 81 hybrids (Poll Dorset${\times}$Small Tailed Han sheep) were used to detect the polymorphisms in exon 6 region of sheep BMPRIB gene. A fragment of approximately 190bp was amplified by one pair of primers, the polymorphism was revealed from the analysis of three populations by the technique of PCR -SSCP, and a mutation from A to G at 746 of the coding region was confirmed by sequencing in several individual. Statistical results indicated the distribution of allele B (with a A$\longrightarrow$G mutation) and A (without mutation) or genotype AA, AB and BB frequencies differed in three populations. BB genotype (44.55%) and B allele (66.34%) frequencies of Small Tailed Han sheep were higher than those of the others. Analysis of variance showed that the polymorphism of BMPRIB gene was associated with positive effect on litter size traits. The means of genotype BB and AB were about 1.04 and 0.74 more than genotype AA for litter size (p<0.05). Analysis of BMPRIB genotype effects on litter size in three populations indicates the existence of genotype BB or B allele increases the litter size. It suggested that the polymorphism in exon 6 (at 746 in the coding region) of sheep BMPRIB gene may be used as a marker for early selection of prolificacy in sheep.

Analysis of the roles of interphase, waviness and agglomeration of CNT in the electrical conductivity and tensile modulus of polymer/CNT nanocomposites by theoretical approaches

Zhu, Jia-Ming,Zare, Yasser,Rhee, Kyong Yop Elsevier 2018 Colloids and surfaces. A, Physicochemical and engi Vol.539 No.-

<P><B>Abstract</B></P> <P>This study focuses on the roles of interphase between polymer matrix and CNT, waviness and agglomeration of CNT on the electrical conductivity and tensile modulus of polymer/CNT nanocomposites (PCNT). Several simple equations for percolation threshold, effective volume fraction of CNT and the fraction of networked CNT above percolation threshold are expressed assuming the roles of the mentioned parameters. After that, two proper models are applied to express the conductivity and modulus of PCNT by the influences of interphase, waviness and agglomeration. Both conductivity and modulus show similar correlations with these parameters. It is shown that interphase thickness (t), electrical conduction of CNT (σ<SUB>N</SUB>) and modulus of CNT network (E<SUB>N</SUB>) largely affect the electrical conductivity and tensile modulus of PCNT. The best relative conductivity (ratio of PCNT conductivity to polymer conduction) as 14*10<SUP>17</SUP> is achieved by the highest levels of t=20nm and σ<SUB>N</SUB> =2.5*10<SUP>5</SUP> S/m, while t <6nm produces the relative conductivity of 0.3*10<SUP>17</SUP>. Furthermore, the tensile modulus of PCNT improves by 2100% at t=20nm and E<SUB>N</SUB> =1900GPa, whereas about 110% improvement of modulus is shown by t <6nm at different “E<SUB>N</SUB>”.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Conductivity and mechanical performances of polymer CNT nanocomposites are studied. </LI> <LI> The roles of interphase, waviness and agglomeration of CNT are determined. </LI> <LI> Both conductivity and modulus show similar correlations with these parameters. </LI> <LI> Interphase thickness, conduction and modulus of CNT mainly affect the properties of PCNT. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Key Point Detection in 3D Reconstruction Based On Human-Computer Interaction

Zhu Shi Wei,Zhang Xiao Guo,Lv Jia Dong,Wang Qing 보안공학연구지원센터 2015 International Journal of Multimedia and Ubiquitous Vol.10 No.1

Aiming at solving problem of points’ redundancy caused by full automatically detecting points and the problem of large workload caused by picking all points manually, I advanced a new method of picking points which is based on Human-Computer Interaction in our 3D reconstruction platform after automatically detecting points. We first detected and matched points automatically and got the homograph matrix between two images, then projected points which were picked by hand on the one image to the other image, at last we would search the interesting feature points in the neighborhood of corresponding points in the two images. Experiments have shown that this method decreases the redundancy brought by large number of points and successfully finds the important feature points, so it lays a good foundation for 3D reconstruction.

Microwave Assisted Synthesis of Graphene-Bi2MoO6 Nanocomposite as Sono-Photocatalyst

Jia-Yao Tang,Lei Zhu,Jia-Yi Fan,Chen-Sun,Won-Chun Oh 한국재료학회 2022 한국재료학회지 Vol.32 No.1

In this investigation, Bi2MoO6 deposited graphene nanocomposite (BMG) was synthesized using a simple microwave assisted hydrothermal synthesis method. The synthesized BMG nanocomposite was characterized by X-ray diffraction, transmission electron microscopy, scanning electron microscopy with energy dispersive X-ray analysis, and photocurrent analysis. The study revealed that the catalysts prepared have high crystalline nature, enhanced light responsive property, high catalytic activity, and good stability. XRD results of BMG composite exhibit a koechlinite phase of Bi2MoO6. The surface property is shown by SEM and TEM, which confirmed a homogenous composition in the bulk particles of Bi2MoO6 and nanosheets of graphene. The catalytic behavior was investigated by the decomposition of Rhodamine B as a standard dye. The results exhibit excellent yields of product derivatives at mild conditions under ultrasonic/visible light-medium. Approximately 1.6-times-enhanced sono-photocatalytic activity was observed by introduction of Bi2MoO6 on graphene nanosheet compared with control sample P25 during 50 min test.

The F-box Protein KIB1 Mediates Brassinosteroid-Induced Inactivation and Degradation of GSK3-like Kinases in <i>Arabidopsis</i>

Zhu, Jia-Ying,Li, Yuyao,Cao, Dong-Mei,Yang, Hongjuan,Oh, Eunkyoo,Bi, Yang,Zhu, Shengwei,Wang, Zhi-Yong Elsevier 2017 Molecular cell Vol.66 No.5

<P><B>Summary</B></P> <P>The glycogen synthase kinase-3 (GSK3) family kinases are central cellular regulators highly conserved in all eukaryotes. In <I>Arabidopsis</I>, the GSK3-like kinase BIN2 phosphorylates a range of proteins to control broad developmental processes, and BIN2 is degraded through unknown mechanism upon receptor kinase-mediated brassinosteroid (BR) signaling. Here we identify KIB1 as an F-box E3 ubiquitin ligase that promotes the degradation of BIN2 while blocking its substrate access. Loss-of-function mutations of KIB1 and its homologs abolished BR-induced BIN2 degradation and caused severe BR-insensitive phenotypes. KIB1 directly interacted with BIN2 in a BR-dependent manner and promoted BIN2 ubiquitination in vitro. Expression of an F-box-truncated KIB1 caused BIN2 accumulation but dephosphorylation of its substrate BZR1 and activation of BR responses because KIB1 blocked BIN2 binding to BZR1. Our study demonstrates that KIB1 plays an essential role in BR signaling by inhibiting BIN2 through dual mechanisms of blocking substrate access and promoting degradation.</P> <P><B>Highlights</B></P> <P> <UL> <LI> KIB1 is an essential positive regulator in brassinosteroid signaling </LI> <LI> KIB1 mediates BR-induced ubiquitination and degradation of GSK3 kinase BIN2 </LI> <LI> KIB1 binding to BIN2 prevents BIN2-substrate interaction and promotes BIN2 degradation </LI> </UL> </P> <P><B>Graphical Abstract</B></P> <P>[DISPLAY OMISSION]</P>