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Hyeongyeong Choi,Hyun-Jeong Oh,Ji-Su Shin,MyeongSeob Lim,Sung-Kyung Kim,Hee-Tae Kang,Sung-Soo Oh,Sang-Baek Koh 대한직업환경의학회 2019 대한직업환경의학회지 Vol.31 No.-
Background: Shift work has well-known adverse effects on health. However, few studies have investigated the relationship between shift work and hepatic disorders. This study aimed to evaluate the association between shift work and abnormal level of liver enzymes. Methods: The aggregated data from the 2007–2009, 2010–2012, and 2013–2015 cycles of the Korea National Health and Nutrition Examination Survey was used for this study. The χ2 test and multiple logistic regression analysis were used to assess relationship between shift work and abnormal level of liver enzymes stratified by gender. Results: The odds ratio (OR) of abnormal serum level of alanine aminotransferase (abnormal ALT) in female shift workers was higher with 1.31 (95% confidence interval: 1.00–1.71) compared with day workers after adjusting for covariates. After dividing into subgroups of the shift work pattern, the ORs of abnormal liver enzymes for each pattern compared with day work were not significantly higher. Conclusions: This study provides limited support for the hypothesis that shift work is related to liver enzyme abnormalities, but offers some evidence in favor of the idea that shift work affects female workers more than males on abnormal ALT. Further studies are needed to define the relationship between shift work and abnormal liver enzymes to be carried out as well as the gender difference in the association.
이현경 ( Hyeongyeong Lee ),김경수 ( Kyeongsu Kim ),최동필 ( Dongphil Choi ),최원종 ( Wounjong Choi ) 한국보건정보통계학회(구 한국보건통계학회) 2020 보건정보통계학회지 Vol.45 No.2
Objectives: The occurrence of injury causes physical and mental health problems and socioeconomic losses. Identifying the extent of injury to farmers is an important basic data for preventing, treating and rehabilitating injuries to farmers. The purpose of this study was to comparison the injury rate and injury ratio by farmers and non-farmers by year, and to analyze the impact factor of injury occurrence. Methods: The data sources used in this study are Community Health Survey as national accreditation statistics. The annual injury rates were estimated for farmers and non-farmers aged 19 or older in the past year occurred during daily life and work. The annual injury rates of farmers and non-farmers were weighted according to the guidelines for using raw data. The analysis method was frequency and percent analysis, weighted fraction (%), standard error (SE), chi-square, logistic regression. Results: The annual injury rate of farmers was 8.6% (odds ratio, OR=1.14, 95% confidence interval, 95% CI=1.04-1.24) in 2013, 5.9% (OR=1.24, 95% CI=1.13- 1.36) in 2014, 9.1% (OR=1.23, 95% CI=1.14-1.33) in 2015, 9.5% (OR=1.23, 95% CI=1.14-1.33) in 2016, 8.9% (OR=1.33, 95% CI=1.23-1.44) in 2017. The annual injury rate of non-farmers was 6.9% in 2013, 4.9% in 2014, 7.6% in 2015, 7.9% in 2016, 6.6% in 2017. Conclusions: The annual injury rate of farmers was higher than non-farmers. The annual rate of injury for farmers is about 1.2 times higher than non-farmers each year. For farmers at high risk of injury, safety education related to injury prevention is continuously needed.
상황기반 학습시스템의 영향과 설계방법에 대한 실험적 고찰
양현경(Hyeongyeong Yang),류호경(Hokyoung Ryu),이장선(Jangsun Lee) 한국HCI학회 2012 한국HCI학회 학술대회 Vol.2012 No.1
기존 e-learning 시스템을 통한 학습의 단점중의 하나는 상황을 통한 경험적 지식을 제공할 수 없다는 것으로 요약될 수 있다. 이러한 단점을 극복하고자 최근의 기능성 게임(serious games) 혹은 모바일 기반 학습시스템 (mobile learning)은 학습내용과 상황을 동시에 제공하여 사용자들의 학습능력 강화를 도모하고 있다. 본 논문은 이러한 상황기반 학습시스템(context-rich learning systems)을 통한 학습효과를 실험적으로 검증하고, 이를 Self-Determination Theory (SDT)로 설명하고자 한다. 이를 통하여 상황정보가 제공하는 내적 동기화 과정이 새로운 학습시스템의 설계에 반영되어질 수 있도록 하는 설계 가이드라인을 제공하고자 한다. A critical limitation of the previous e-learning systems is that they have barely presented contextual information that can be applicable for strengthening a learner's knowledge structure. To reflect this drawback, both serious games and mobile learning systems have sought for a way to embody the contextual information in its way to deliver the learning content. The present study empirically demonstrated that the learning effect from the context-rich learning system was relatively stronger than the other context-independent learning systems, and this could be seen by the differences in the internal motivation respect. Also, the outcomes from this study suggested some relevant design guidelines to promote internal motivation in the context-rich system.
Kim Hyeongyeong,Kim Youngdoe,Kang Jiho 대한감염학회 2021 Infection and Chemotherapy Vol.53 No.3
We aimed to evaluate the safety and effectiveness of darunavir (DRV) in the treatment of human immunodeficiency virus-1 (HIV-1) infection in Korea. From October 29, 2010, 225 eligible patients with HIV-1 infection receiving DRV were enrolled. DRV was administered with other antiretroviral agents, and followed for 24 weeks. The primary objective was safety evaluation, and effectiveness was assessed by viral load and CD4 T cell counts after 12 weeks and 24 weeks. Adverse drug reactions occurred in 18 patients (9.2%); diarrhea was the most common. Viral load was controlled (<400 copies/mL) in 90.9% of patients. CD4 T cell counts were increased 45.0/mm3 significantly at Week 12 (P = 0.0002), and 70.5/mm3 at Week 24 (P <0.0001). DRV safety and effectiveness was consistent with previous studies.