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( Haemin Kim ),( Kuijae Lee ),( Jongchan Chae ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.11
Bacillus subtilis HM1 was isolated from the rhizosphere region of halophytes for its antifungal activity against Colletotrichum acutatum, the causative agent of anthracnose. Treatment of postharvest apples with the cell culture or with a cell-free culture supernatant reduced disease severity 80.7% and 69.4%, respectively. Both treatments also exhibited antifungal activity against various phytopathogenic fungi in vitro. The antifungal substances were purified and analyzed by acid precipitation, gel filtration, high-performance liquid chromatography, and matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). Three compounds were identified as fengycin, iturin, and surfactin. The MALDI-TOF/ TOF mass spectrum revealed the presence of cyclized fengycin homologs A and B, which were distinguishable on the basis of the presence of either alanine or valine, respectively, at position 6 of the peptide sequence. In addition, the cyclized structure of fengycin was shown to play a critical role in antifungal activity.
Haemin Im,Changkun Park 한국전기전자학회 2019 전기전자학회논문지 Vol.23 No.2
We propose a low-loss on-chip transformer using an auxiliary primary part (APP) for an output matching network for fully integrated CMOS power amplifiers. The APP is designed using a fifth metal layer while the primary and secondary parts are designed using a sixth metal layer with a width smaller than that of the primary and secondary parts of the transformer to minimize the substrate loss and the parasitic capacitance between the primary and secondary parts. By adapting the APP in the on-chip transformer, we obtain an improved maximum available gain value without the need for any additional chip area. The feasibility of the proposed APP structure is successfully verified.
Truthful Electric Vehicle Charging via Neural-Architectural Myerson Auction
Haemin Lee,Soyi Jung,Joongheon Kim 한국통신학회 2021 ICT Express Vol.7 No.2
The electric vehicle (EV) market increases due to the benefits of reducing greenhouse gas emissions using renewable energy resources. In this context, the charging scheme of electric vehicles in charging stations (CSs) is also important. Electronic devices’ charging between EV and multiple CS should consider EV’s short battery capacity, long charging time, residual energy in each CS, and time of use (ToU) for charging. In this paper, multiple CSs compete to offer electricity charging to a single EV. Based on this need, this paper proposes a deep learning-based auction which increases the charging amounts using Myerson auction while preserving truthfulness.
Extracellular S100A4 negatively regulates osteoblast function by activating the NF-κB pathway
( Haemin Kim ),( Yong Deok Lee ),( Min Kyung Kim ),( Jun-oh Kwon ),( Min-kyoung Song ),( Zang Hee Lee ),( Hong-hee Kim ) 생화학분자생물학회(구 한국생화학분자생물학회) 2017 BMB Reports Vol.50 No.2
Patients with inflammatory bone disease or cancer exhibit an increased risk of fractures and delayed bone healing. The S100A4 protein is a member of the calcium-binding S100 protein family, which is abundantly expressed in inflammatory diseases and cancers. We investigated the effects of extracellular S100A4 on osteoblasts, which are cells responsible for bone formation. Treating primary calvarial osteoblasts with recombinant S100A4 resulted in matrix mineralization reductions. The expression of osteoblast marker genes including osteocalcin and osterix was also suppressed. Interestingly, S100A4 stimulated the nuclear factor-kappaB (NF-κB) signaling pathway in osteoblasts. More importantly, the ex vivo organ culture of mouse calvariae with recombinant S100A4 decreased the expression levels of osteocalcin, supporting the results of our in vitro experiments. This suggests that extracellular S100A4 is important for the regulation of bone formation by activating the NF-κB signaling pathway in osteoblasts. [BMB Reports 2017; 50(2): 97-102]