만성폐쇄성 폐질환 환자에서 적혈구 항산화효소의 변화

국기용,이만재,조희충,임영국,박일,김원식,이승일,이병래 朝鮮大學校 附設 醫學硏究所 1993 The Medical Journal of Chosun University Vol.18 No.1

Toxic oxygen free radicals have been implicated as important pathologic mediators in many clinical disordesrs. Enhandng the intracellular content of antioxidant enzymes can provide means of limiting biological damage caused by oxygen free radicals. Many investigations have examined the potential of various oxyradical scavengers to modulate oxyradical injury. The oxygen free radicals play a role in the pathogenesis of chronic obstructive pulmonary disease. To investigate the pulmonary oxyradical injury and the protective role of antioxidant enzymes, author measured the amount of thiobarbituric acid reactants, the activiteies of antioxidant enzymes (superoxide dismutase, glutathione peroxidase, and catalase) and the sulfhydryl groups in serum and red blood cells from the chronic obstructive pulmonary disease groups and the normal controls. The thiobarbituric acid reactant in chronic obstructive pulmonary disease groups was increased than the controls in both serum and red blood cells, and the superoxide dismutase activity in red blood cells was no statistically difference in both groups. But, the glutathione peroxidase and catalase activities were lowered in chronic obstructive pulmonary disease groups than the controls. The sulfhydryl groups in serum and red blood cells were no statistically difference in both groups. These results suggest that the increased thiobarbituric acid reactant in chronic obstructive pulmonary disease groups mean oxygen radical toxicity, and the decreased glutathione peroxidase and catalase activities may play a role in cellular injury.

혈액질환에서의 핵의학적 이용

김병국 한국의학사 1985 診斷과治療 Vol.5 No.4

D-penicillamine 투여에 의한 무기수은중독의 치료효과

유병국 카톨릭대학산업의학센타 산업의학연구소 1978 韓國의 産業醫學 Vol.17 No.1

The author has experienced two cases of chronic inorganic mercury poisoning that occurred at a tungsten rod manufacturing factory. The mercury concentrations in workroom air were 0.1 and 0.45mg/㎥. The diagnosis was established by clinical and laboratory findings. After 14 weeks of treatment with oral D-penicillamine, both cases were discharged without any complication. The effect of D-penicillamine on mercury poisoning were briefly reviewed.

양성과 음성 정신분열증 환자의 인지 장애에 관한 연구

이병국,이형영 大韓神經精神醫學會 1988 신경정신의학 Vol.27 No.6

This study was conducted to compare the differences in cognitive dysfunction between positive and negative schizophrenics. The subjects of the study consisted of 30 normal controls, 30 positive schizophrenics and 30 negative schizophrenics. Garner-typed card sorting, Bender-Gestalt test and mini-mental state test were administered to each subject. The result were as follows: 1) For the card sorting of low discriminability, the sorting times were significantly different among the three groups: the longest in the negative schizophrenics and the shortest in the controls(P<0.01). But, there was no significant difference between positive and negative schizophrenic groups. 2) For the Bender-Gestalt test, the Z-scores were significantly different among the three grops: the highest in the negative schizophrenics and the lowest in the controls(P<0.01), and the Z-score was significantly lower in the positive than in the negative schizophrenic groups(P<0.01). 3) For the mini-mental state test, the scores were significantly different among the three groups: the highest in the controls and the lowest in the schizophrenics(P<0.01). In the comparison between positive and negative schizophrenic groups, the score was significantly higher in the former than in the latter(P<0.01).

지역난방용 매설배관의 열응력 흡수에 관한 연구

남궁재관,신병국 한국공작기계학회 2002 한국공작기계학회 추계학술대회논문집 Vol.2002 No.-

초등학생들의 비만요인에 관한 연구

손정례,이병국 순천향대학교 산업의학연구소 1998 순천향산업의학 Vol.4 No.1

In order to investigate the factors of elementary school pupil's obesity, 1031 children were selected from two elementary schools in Kwnangju. The Period of this study was from February 9 to 14, 1998. Structured questionnaire forms were provided to all study pupils to identify the presence of obesity and demographic characteristics as sex, parent's occupation and education level, and food habits, leisure activities, exercise, etc. The results of the study were as follows. The factors of elementary school pupil's obesity are father's physical condition, intaking of snack foods at night, taking sweety foods, time of watching TV, and after school activities. While pupil's obesity were statistically significant relationship with leisure activities, but no relationships with type of exercise and amount of exercise. In discriminating analysis, the factors of elementary school pupil's obesity are well-taking any foods, intaking of snack foods at night, amount of taking foods leisure activities, time of watching TV, taking favorite foods, father's physical condition, overeating habits, and after school activities. The result of this study shows that major cause of elementary school pupil's obesity are eating habits. Therefore nutritional education programs for obese children should be designed for eating habits and food balance.

지역난방용 매설배관의 마찰력에 관한 연구

낭궁재관,신병국 한국공작기계학회 2003 한국공작기계학회 춘계학술대회논문집 Vol.2003 No.-

Carboxymethyl-chitin 제조공정의 단순화

한상문,안병제,김용우,김용범,유국현,이승진 대한화학회 2001 대한화학회지 Vol.45 No.4

CM-chitin은 화장품 분야에서 보습제, 유연제, 피부관리를 위한 세포활성제 및 미백제등으로 다양하게 이용되고 있는 것으로 알려져 있다. 본 연구에서는 CM-chitin제조공정을 기존의 방법에서 몇가지 절차를 배재하여 단순화 하였다. Chitin분말을 NaOH와 혼합하고 16hrs 동안 동결 및 교반을 통해 CICH_(2)COONa와 isopropyl alcohol혼합액을 첨가하였다. 그 결과 높은 치환도의 CM-chitin을 얻을 수 있었다. The water soluble carboxymethyl-chitin(CM-chitin) has been well known to be very useful to the cosmetic field as a moisturizer, a smoothener, a cell activater and a cleaner for face skin conditioning. In this study, the preparation process of CM-chitin was simplified with elimination of some procedures in the conventional method. The chitin powder was mixed with sodium hydroxide solution. And then a mixture of sodium monochloroacetate(or monochloroacetic acid) and isopropyl alcohol(or a mixed solution with water and isopropyl alcohol) was added to thorough the agitation and the freezing during 16 hours. The CM-chitin with a high degree of substitution by the improved process was obtained.

고온 접촉식 탐상용 초음파 탐촉자 개발 및 평가

김기복,김병극,이승석,윤남원,윤동진,안윤국 한국비파괴검사학회 2003 한국비파괴검사학회지 Vol.23 No.1

고온(500℃) 환경에서 접촉식 탐상이 가능한 초음파 탐촉자를 개발하고 평가하였다. 고온용 탐촉자는 Curie 온도가 600 ℃ 이상인 bismuth titanate 계열의 압전세라믹 소자, 텅스텐 분말과 inorganic binder를 혼합한 후면재, 알루미나 튜브, 전면재, 하우징 등으로 구성되었다. 기본 공진주파수가 각각 1.04 및 2.08 ㎒의 2 종류 탐촉자를 제작하였으며 각종 고온용 커플런트의 온도특성을 시험하였다. 개발된 고온용 탐촉자를 이용하여 강재 시편을 대상으로 시편에서의 초음파 반사신호를 측정한 결과 시편의 온도가 증가함에 따라 반사신호의 크기는 감소하였다. 고온에서 반복측정 실험결과 500℃에서 연속적인 접촉식 초음파 탐상이 가능한 것으로 나타났다. Piezoelectric ultrasonic transducers for high temperature contact measurement were developed. These high temperature ultrasonic transducers (HTUT) consisted of bismuth titanate piezoceramic element whose Curie temperature is higher than 600℃, a backing material of the mixture of tungsten powder and inorganic binder, an inner alumina tube, a wear plate and a housing. The operational frequencies of the HTUT were 1.04 and 2.08 ㎒, respectively. Various commercially available couplant for high temperature were evaluated and compared. As a couplant for high temperature ultrasonic testing between HTUT and test specimen, gold epoxy was selected. The peak amplitude of pulse-echo signals from steel test specimen decreased with increasing temperature. The operational temperature of the HTUT reached up to 500℃ at which the continuous contact measurement was possible.

구강외과 영역의 수술에 있어서 Emazon의 진통·소염효과

김창수,엄인웅,민병국 최신의학사 1990 最新醫學 Vol.33 No.8