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안연정 ( Yeon Jeong Ahn ),김태효 ( Tae Hyo Kim ),문성원 ( Sung Won Moon ),최수녕 ( Su Nyoung Choi ),김현진 ( Hyun Jin Kim ),정운태 ( Woon Tae Jung ),이옥재 ( Ok Jae Lee ),고경혁 ( Gyung Hyuck Ko ) 대한소화기학회 2011 대한소화기학회지 Vol.58 No.3
Xanthogranulomatous cholecystitis is an unusual inflammatory disease of the gallbladder characterized by severe proliferative fibrosis and the accumulation of lipid-laden macrophages in areas of destructive inflammation. Its macroscopic appearance may occasionally be confused with gallbladder carcinoma. We present a case of perforated xanthogranulomatous cholecystitis presenting as biloma. An 80-year-old woman was referred to our hospital with a 1-week history of abdominal pain and febrile sensation. Abdominal CT showed a biloma in the subhepatic area. The follow-up CT showed that the biloma increased in size. Therefore, ultrasonography-guided aspiration was performed. The aspirated fluid/serum bilirubin ratio was greater than 5, which was strongly suggestive of bile leakage complicated by perforated cholecystitis. She underwent a laparoscopic cholecystectomy with cyst aspiration and adhesiolysis. A histological diagnosis of perforated xanthogranulomatous cholecystitis was made. (Korean J Gastroenterol 2011;58:153-156)
다발성 뇌경색을 동반한 Streptococcus agalactiae에 의한 감염심내막염 2예
박진용,최수녕,김현옥,정용근,황진용,김종우,배인규 대한감염학회 2006 감염과 화학요법 Vol.38 No.5
최근 기저질환을 가진 나이 많은 성인에서의 침습성 S.agalactiae 감염증의 보고가 늘어나고 있다. S. agalactiae감염심내막염은 비교적 드물지만 중증의 감염증으로 전신적 색전증과 광범위한 판막파괴로 인한 심부전이 잘 동반되므로 판막치환수술이 필요한 경우가 많다. 저자들은 기저질환으로 당뇨병과 알코올 중독이 있는 환자에서 발생한 S. agalactiae 감염심내막염 2예를 경험하였기에 드문 증례로 생각되어 문헌고찰과 함께 보고하는 바이다. The higher incidence of Streptococcus agalactiae infection in the newborns and pregnant women had been well recognized. The incidence of invasive S. agalactiae infection was recently increasing in both elderly adults and those with comorbid conditions such as diabetes mellitus, liver cirrhosis, malignancy, and abnormalities in immune responses. We report our experience with two diabetic middle-aged men who suffered from S.agalactiae infective endocarditis. Case 1) A 58-year-old man with diabetes mellitus and chronic alcoholism presented with fever and both lower legs weakness. An echocardiography showed two vegetations on the mitral valve. S. agalactiae was identified from blood cultures. He was treated with penicillin G and gentamicin, and he underwent mitral valve replacement surgery because of persistent fever and newly developed brain infarcts. One month later, an amputation of the left lower leg was performed for the embolic gangrene of left lower leg. Case 2) A 57-year-old diabetic man was admitted to our hospital because of fever and left shoulder pain. He had received the incision and drainage to treat left shoulder joint septic arthritis, but he had a continuous fever. On 5th day of admission, culture of pus from the left shoulder joint revealed S. agalactiae. An echocardiography showed a vegetation on the posterior mitral leaflet. He was treated with penicillin G and gentamicin. On 18th day of admission, a mitral valve replacement surgery was performed. He was discharged without recurrence.