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안석용 ( Seok Yong Ahn ),이영복 ( Young Bok Lee ),이광호 ( Kwang Ho Lee ),임현교 ( Hyun Kyo Lim ),이원수 ( Won Soo Lee ),안성구 ( Sung Ku Ahn ),최응호 ( Eung Ho Choi ) 대한피부과학회 2006 大韓皮膚科學會誌 Vol.44 No.6
Background: Stellate ganglion block has been proposed as one of the effective therapetic modalities for herpes zoster. However, the effect on the reduction of acute herpes zoster pain and postherpetic neuralgia is not well known. Objective: To evaluate the reduction of acute herpes zoster pain and the prevention of postherpetic neuralgia by stellate ganglion block. Methods: Twenty one patients with herpes zoster were included in this study, and were divided into two groups: the group treated with I.V acyclovir, analgesics and stellate ganglion block during 7-days of a hospitalization period, and a control group which were treated with I.V acyclovir and analgesics alone. To evaluate it`s effect on pain, the score of pain presented by patients, where initial pain was defined as 100 and no pain defined as 0, was recorded and compared between the groups. Results: An average day required for the relief of pain was significantly shorter in the treated group than the control group: the average number of days needed to reduce the pain score from 100 to 50, implicating relief of acute pain, was 2.3 days, compared to 3.7 days in the control group (p=0.036). The total duration of pain, implicating postherpetic neuralgia, was also significantly shorter in the treated group (17.4 days) than the control group (42.3 days) (p=0.035). Conclusion: Stellate ganglion block is an effective method which can be used to relieve acute herpes zoster pain involving the trigerminal and cervical nerves, and can prevent postherpetic neuralgia. (Korean J Dermatol 2006;44(6):681~687)
안석용 ( Seok Yong Ahn ),박하나 ( Ha Na Bak ),최응호 ( Eung Ho Choi ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.10
A 7 year-old boy visited our hospital with a 2 week history of inflammatory, pustular, tender patches and plaques on the right scalp and face area. He had been treated with topical steroid and antibiotics in a private clinic. In a KOH smear mount, multiple hyphaes and spores appeared on stratum corneum of the outer root sheath layer of his hair. The diagnosis of kerion celsi induced by dermatophytes was made. The patient was treated with oral griseofulvin, and on the 2nd day after starting treatment, multiple erythematous and tendered subcutaneous nodules occurred on his shin. A photosensitive dermatitis like lesion also occurred on his periorbital area. Griseofulvin changed to terbinafine. On the 6th day after treatment, the skin lesions on his face and scalp had improved, as had his shin lesions. The interest of this case lies in the unusual association of kerion and erythema nodosum, of which only eleven cases have been reported in dermatologic literature, and all cases were kerion induced Trichophyton species. (Korean J Dermatol 2007;45(10):1101∼1104)
안석용 ( Seok Yong Ahn ),박화영 ( Hwa Young Park ),이원수 ( Won Soo Lee ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.4
Morphea is a sclerotic connective tissue disorder and it is thought to be caused by the decreased activity of collagenase. Various therapeutic modalitiessuch as topical steroid and systemic steroid, antimalarial agents, cyclosporine and phototherapy have been shown to be effective to treat this illness. Recently, PUVA and UVA1 phototherapy for localized scleroderma have been shown to have excellent efficacy. But PUVA and UVA1 phototherapy also have some disadvantages. So another phototherapy modality is warranted. Herein we report on a case of a 7 year female patient with linear scleroderma and she obtained a successful result with NBUVB phototherapy. (Korean J Dermatol 2009;47(4):494~497)
안석용 ( Seok Yong Ahn ),이윤희 ( Yoon Hee Lee ),전수영 ( Soo Young Jeon ),임백근 ( Baek Keun Lim ),이원수 ( Won Soo Lee ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.7
We report a case of Hunter syndrome in a 4 year old boy, who presented with firm skin colored papules and nodules that coalesce to form a reticular pattern (pebbling of the skin) with extensive Mongolian spots. The lesions are arranged bilaterally and symmetrically over the scapulae, upper arm and lateral aspects of the thighs. He also has low intelligence, coarse face, saddle nose and claw hand contracture of both hands. The result of qualitative analysis of urine was positive for dermatan sulfate and heparan sulfate. And enzyme activity of iduronate-2-sulfatase is decreased in plasma and leukocyte. A skin biopsy specimen section stained with hematoxylin-eosin showed widely separated collagen bundles in the dermis associated with mucin deposition. (Korean J Dermatol 2008;46(7):928~932)
두피에 발생한 속발성 피부 형질세포종,면역글로블린 D 유리경쇄 람다형
오윤석 ( Yoon Seok Oh ),안석용 ( Seok Yong Ahn ),전수영 ( Soo Young Jeon ),이원수 ( Won Soo Lee ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.4
Cutaneous plasmacytoma (CP) is a localized collection of monoclonal plasma cells in the skin. The disease is divided into primary cutaneous plasmacytoma and secondary cutaneous plasmacytoma groups. Secondary cutaneous plasmacytoma, which is so rare as to occur in only 2% of myeloma cases, usually represents terminal expression of the primary diseases and is associated with increased tumor burden. CP can occur at any site of the skin, but we could find only 1 case in English literature related to scalp metastasis alone. Also serum and urine electrophoresis, tissue immunohistochemistry for IgD are not usually conducted in the laboratory. IgDλ subtype seems to be another value to report. We report a case of secondary cutaneous plasmacytoma, IgDλ type which developed on the scalp alone of a 41-year-old woman, with a review of related literatures. (Korean J Dermatol 2008;46(4):525~528)
우발적 국소성 가시세포분리성 이각화증의 소견을 보인 화농성 육아종
박화영 ( Hwa Young Park ),안석용 ( Seok Yong Ahn ),홍승필 ( Seung Phil Hong ),전수영 ( Soo Young Jeon ),박하나 ( Ha Na Bak ),이상훈 ( Sang Hoon Lee ),안성구 ( Sung Ku Ahn ) 대한피부과학회 2008 大韓皮膚科學會誌 Vol.46 No.12
Incidental focal acantholytic dyskeratosis (IFAD) has been described for various cutaneous lesions. A 58-year-old man presented with a purple colored, 5 mm crusted papule on the back. An excisional biopsy was performed and histopathological examination showed angiomatous tissue occurring in a discrete mass. It was enclosed by a collarette of acanthotic epidermis. The angiomatous tissue comprised a variably dilated network of blood-filled capillaries, which was surrounded by myxoid stroma. Hyperkeratosis, acantholysis, dyskeratosis and intraepidermal clefts were also focally present. Correlation of the clinical features and the histopathology results established a diagnosis of pyogenic granuloma showing IFAD. (Korean J Dermatol 2008;46(12):1664∼1666)
지속적 안와 부종 후에 발생한 연부조직염 양상의 비강 CD56 양성 NK/T 세포 림프종
김민정 ( Min Jeong Kim ),안석용 ( Seok Yong Ahn ),구자웅 ( Ja Woong Goo ),이원수 ( Won Soo Lee ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.7
Recently another distinct subtype of lymphoma has been discovered, the natural killer (NK)T cell lymphoma, which can involve the skin in a primary or secondary fashion. NK/T cell lymphoma is characterized by the biphenotype expression of the T-cell marker and NK cell marker, especially CD56. These CD56+ lymphomas are further subdivided into nasal NK/T-cell lymphomas and non-nasal NK/T-cell lymphomas. We report a case of primary nasal NK/T cell lymphoma, which showed as an atypical cellulites-like lesion on the face. The patient had suffered with recurrent orbital swelling for several years before diagnosis. (Korean J Dermatol 2007;45(7):692∼696)