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도로교통소음과 대기질 및 도시 형태간의 관계 파악을 위한 방법론 고찰
류훈재(Hunjae Ryu),김윤희(Yunhee Kim),전범석(Bum Seok Chun),박인권(In Kwon Park),장서일(Seo Il Chang) 한국소음진동공학회 2015 한국소음진동공학회 학술대회논문집 Vol.2015 No.4
In urban areas, continuous monitoring and management of urban environmental noise and air quality are increasingly important for people’s health impact and well-being. Especially, the road traffic, which is one major indicator of urban forms such as population, building, transportation and land-use, etc., is the same emission source of urban noise and air quality. Furthermore it is required to figure out integrated relationship because the road traffic and other urban form indicators are interrelated. Therefore, this study aims to investigate the relationship among road traffic noise, air quality and urban forms, and to provide and consider the methodology. Fulton County in Georgia state of USA, where is the principal county of the Atlanta metropolitan area, is selected for this study. First, the noise level exposed to residents and the concentration of PM2.5 are calculated as dependent variables. Second, the representative values for noise level, the concentration of PM2.5 and urban form indicators are averaged over grid cells of 200×200m for Fulton County. And then, the relationship between noise and urban forms, and the relationship between air quality and urban forms are respectively estimated by spatial statistical model. In addition, the integrated relationship among them is analyzed by seemingly unrelated regression model. This well-estimated model could be useful for preliminary urban planning and sustainable environmental management, and it could make it possible to design integrated and systematic planning.
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해마세포주에서 Cycloheximide에 의한 세포사의 억제와 Bcl-2 mRNA의 발현 유도
유숙희,김윤희 경희대학교 생명자원과학연구원 1998 遺傳工學論文集 Vol.10 No.-
Neuronal cell death regulates the number of synapse and neuronal cells to form neural network during the development of the mammalian nervous system. A hippocampal stem cell line HiB5, which is immortalized by the temperature sensitive SV 40 T antigen, undergoes neuronal differentiation at non-permissive temperatures. During the differentiation process, many cells do not survive but undergo apoptosis accompanied by DNA fragmentation. Here we report that cycloheximide (CHX), a inhibitor of protein synthesis, prevented apoptosis of HiB5 cells and increased the expression of Bcl-2 mRNA. These results implicate that CHX may increase the cell survival not only by preventing the protein synthesis of death genes but also by inducing the expression of survival genes such as Bcl-2.
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